(26 nodes) Cardiac muscle cell development network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tcap	Titin-cap (telethonin). (179 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (191 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (310 aa)
	neb	Nebulin. (6127 aa)
	LOC105917727	Leucine rich repeat containing 10. (283 aa)
	ENSFHEP00000026549	LIM zinc-binding domain-containing protein. (112 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (312 aa)
	alpk2	Uro-adherence factor A. (1382 aa)
	LRRC10B	Leucine rich repeat containing 10B. (325 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (433 aa)
	ENSFHEP00000022237	Alpha-type protein kinase domain-containing protein. (218 aa)
	bmp2	Bone morphogenetic protein 2b. (419 aa)
	LOC105927386	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (420 aa)
	map2k4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (433 aa)
	srf	Serum response factor b. (599 aa)
	LOC105934354	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (616 aa)
	LOC105934355	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (685 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
	LOC105919429	Ankyrin repeat and SOCS box containing 2b. (583 aa)
	adprhl1	ADP-ribosylhydrolase like 1. (358 aa)
	nkx2-5	NK2 homeobox 5. (313 aa)
	maml1	Mastermind-like transcriptional coactivator 1. (957 aa)
	LOC105924010	Uncharacterized protein. (323 aa)
	LOC105924070	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (441 aa)
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (902 aa)
	ENSFHEP00000001722	Ig-like domain-containing protein. (415 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000001722	ENSFHEP00000022237	ENSFHEP00000001722	ENSFHEP00000022237	Ig-like domain-containing protein.	Alpha-type protein kinase domain-containing protein.	0.900
ENSFHEP00000022237	ENSFHEP00000001722	ENSFHEP00000022237	ENSFHEP00000001722	Alpha-type protein kinase domain-containing protein.	Ig-like domain-containing protein.	0.900
ENSFHEP00000026549	csrp3	ENSFHEP00000026549	ENSFHEP00000034557	LIM zinc-binding domain-containing protein.	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.735
ENSFHEP00000026549	neb	ENSFHEP00000026549	ENSFHEP00000030755	LIM zinc-binding domain-containing protein.	Nebulin.	0.498
ENSFHEP00000026549	tcap	ENSFHEP00000026549	ENSFHEP00000011585	LIM zinc-binding domain-containing protein.	Titin-cap (telethonin).	0.490
LOC105924010	nkx2-5	ENSFHEP00000004618	ENSFHEP00000006401	Uncharacterized protein.	NK2 homeobox 5.	0.549
LOC105924010	srf	ENSFHEP00000004618	ENSFHEP00000013718	Uncharacterized protein.	Serum response factor b.	0.933
LOC105927386	map2k4	ENSFHEP00000017643	ENSFHEP00000013850	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.947
atg5	mtor	ENSFHEP00000026190	ENSFHEP00000010587	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.634
atg5	opa1	ENSFHEP00000026190	ENSFHEP00000002766	Autophagy protein 5; Involved in autophagic vesicle formation.	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.584
bmp2	nkx2-5	ENSFHEP00000018050	ENSFHEP00000006401	Bone morphogenetic protein 2b.	NK2 homeobox 5.	0.414
csrp3	ENSFHEP00000026549	ENSFHEP00000034557	ENSFHEP00000026549	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	LIM zinc-binding domain-containing protein.	0.735
csrp3	neb	ENSFHEP00000034557	ENSFHEP00000030755	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Nebulin.	0.439
csrp3	tcap	ENSFHEP00000034557	ENSFHEP00000011585	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Titin-cap (telethonin).	0.699
map2k4	LOC105927386	ENSFHEP00000013850	ENSFHEP00000017643	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.947
mtor	atg5	ENSFHEP00000010587	ENSFHEP00000026190	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.634
neb	ENSFHEP00000026549	ENSFHEP00000030755	ENSFHEP00000026549	Nebulin.	LIM zinc-binding domain-containing protein.	0.498
neb	csrp3	ENSFHEP00000030755	ENSFHEP00000034557	Nebulin.	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.439
neb	tcap	ENSFHEP00000030755	ENSFHEP00000011585	Nebulin.	Titin-cap (telethonin).	0.592
nkx2-5	LOC105924010	ENSFHEP00000006401	ENSFHEP00000004618	NK2 homeobox 5.	Uncharacterized protein.	0.549