STRINGSTRING
LOC105916516 LOC105916516 sh2b3 sh2b3 ENSFHEP00000033024 ENSFHEP00000033024 fgf4 fgf4 LOC105935872 LOC105935872 smpd3 smpd3 ptprc ptprc LOC105939829 LOC105939829 ABI1 ABI1 LOC105933036 LOC105933036 ENSFHEP00000001865 ENSFHEP00000001865 ENSFHEP00000002166 ENSFHEP00000002166 LOC105915540 LOC105915540 LOC105939740 LOC105939740 igf1 igf1 msx1 msx1 EVC EVC epyc epyc chad chad ebp ebp LOC105924010 LOC105924010 gnptab gnptab sp5 sp5 LOC105939150 LOC105939150 ENSFHEP00000005867 ENSFHEP00000005867 mef2d mef2d pdgfc pdgfc anxa6 anxa6 mcph1 mcph1 atg9a atg9a TGFBR2 TGFBR2 nsd2 nsd2 LOC105936696 LOC105936696 LOC105917652 LOC105917652 ENSFHEP00000009799 ENSFHEP00000009799 LOC105925861 LOC105925861 ENSFHEP00000009987 ENSFHEP00000009987 LOC105935786 LOC105935786 kat2a kat2a phex phex SRC SRC mbtps2 mbtps2 ptpn6 ptpn6 gja1 gja1 ENSFHEP00000011863 ENSFHEP00000011863 LOC105918704 LOC105918704 LOC105918234 LOC105918234 kat2b kat2b bbx bbx srf srf med1 med1 edar edar LOC105930854 LOC105930854 atp6ap1 atp6ap1 ENSFHEP00000015248 ENSFHEP00000015248 LOC105935972 LOC105935972 ppib ppib ENSFHEP00000016785 ENSFHEP00000016785 lrrk1 lrrk1 bmp4 bmp4 LOC105930299 LOC105930299 ext2 ext2 LOC105931924 LOC105931924 ep300 ep300 ENSFHEP00000019248 ENSFHEP00000019248 ENSFHEP00000019886 ENSFHEP00000019886 LOC105922161 LOC105922161 LOC105933101 LOC105933101 LOC105932470 LOC105932470 rab23 rab23 LOC105940347 LOC105940347 lepr lepr LOC105935791 LOC105935791 LOC105917264 LOC105917264 LOC105926687 LOC105926687 frem1 frem1 SEMA4D SEMA4D zmpste24 zmpste24 ttc9 ttc9 trip11 trip11 foxn3 foxn3 LOC105935262 LOC105935262 itgb6 itgb6 nab2 nab2 slc38a10 slc38a10 LOC105918304 LOC105918304 bmpr2 bmpr2 glg1 glg1 ENSFHEP00000026670 ENSFHEP00000026670 LOC105935060 LOC105935060 trim45 trim45 pex7 pex7 ENSFHEP00000028182 ENSFHEP00000028182 dhrs3 dhrs3 LOC105918293 LOC105918293 LOC105923080 LOC105923080 LOC105929389 LOC105929389 LOC105935996 LOC105935996 ift80 ift80 sulf1 sulf1 ankrd11 ankrd11 LOC105928446 LOC105928446 LOC105922455 LOC105922455 LOC105934596 LOC105934596 ptpn11 ptpn11 ENSFHEP00000001128 ENSFHEP00000001128 LOC105940353 LOC105940353
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105916516Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
sh2b3SH2B adaptor protein 3. (717 aa)
ENSFHEP00000033024Uncharacterized protein. (61 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
LOC105935872Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (706 aa)
ptprcUncharacterized protein. (989 aa)
LOC105939829Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
ABI1Abl-interactor 1a. (338 aa)
LOC105933036Extracellular serine/threonine protein kinase FAM20C. (585 aa)
ENSFHEP00000001865Stealth_CR4 domain-containing protein. (141 aa)
ENSFHEP00000002166LRRCT domain-containing protein. (286 aa)
LOC105915540Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (732 aa)
LOC105939740Sema domain-containing protein; Belongs to the semaphorin family. (517 aa)
igf1Insulin growth factor I-like protein. (185 aa)
msx1Muscle segment homeobox 1a. (281 aa)
EVCEllis-van Creveld syndrome protein. (969 aa)
epycEpiphycan. (521 aa)
chadChondroadherin. (364 aa)
ebpEBP cholestenol delta-isomerase. (229 aa)
LOC105924010Uncharacterized protein. (323 aa)
gnptabUncharacterized protein. (340 aa)
sp5Uncharacterized protein. (375 aa)
LOC105939150Bone morphogenetic protein 16. (476 aa)
ENSFHEP00000005867Uncharacterized protein. (154 aa)
mef2dMyocyte enhancer factor 2d. (583 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (391 aa)
anxa6Annexin. (672 aa)
mcph1Microcephalin 1. (809 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (883 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1306 aa)
LOC105936696Gla domain-containing protein. (212 aa)
LOC105917652Phosphatase, orphan 2. (243 aa)
ENSFHEP00000009799SH2 domain-containing protein. (116 aa)
LOC105925861Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa)
ENSFHEP00000009987Extracellular matrix protein 1a. (125 aa)
LOC105935786Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
kat2aK(lysine) acetyltransferase 2A. (729 aa)
phexPhosphate regulating endopeptidase homolog, X-linked. (745 aa)
SRCTyrosine-protein kinase. (548 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (499 aa)
ptpn6Protein tyrosine phosphatase non-receptor type 6. (582 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (387 aa)
ENSFHEP00000011863Transmembrane protein 119b. (281 aa)
LOC105918704Ras-related protein Rap-1A. (184 aa)
LOC105918234Tyrosine-protein kinase. (550 aa)
kat2bHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
bbxBBX high mobility group box domain containing. (802 aa)
srfSerum response factor b. (599 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1792 aa)
edarEctodysplasin A receptor. (521 aa)
LOC105930854E1A binding protein p300 a. (2838 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (488 aa)
ENSFHEP00000015248Uncharacterized protein. (235 aa)
LOC105935972Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
ENSFHEP00000016785LRRNT domain-containing protein. (98 aa)
lrrk1Leucine-rich repeat kinase 1. (2034 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
LOC105930299Abl-interactor 1b. (491 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (740 aa)
LOC105931924Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
ep300E1A binding protein p300 b. (2738 aa)
ENSFHEP00000019248Uncharacterized protein. (132 aa)
ENSFHEP00000019886Uncharacterized protein. (184 aa)
LOC105922161Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (422 aa)
LOC105933101Fras1 related extracellular matrix 1b. (1295 aa)
LOC105932470Si:ch211-129c21.1; Belongs to the semaphorin family. (807 aa)
rab23RAB23, member RAS oncogene family. (235 aa)
LOC105940347Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (434 aa)
leprLeptin receptor. (997 aa)
LOC105935791TNF superfamily member 11; Belongs to the tumor necrosis factor family. (269 aa)
LOC105917264Uncharacterized protein. (859 aa)
LOC105926687Vitamin K epoxide reductase complex, subunit 1. (167 aa)
frem1Fras1 related extracellular matrix 1a. (2167 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (871 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (433 aa)
ttc9Tetratricopeptide repeat protein 9A. (250 aa)
trip11Thyroid hormone receptor interactor 11. (1975 aa)
foxn3Checkpoint suppressor 1. (482 aa)
LOC105935262RAP1A, member of RAS oncogene family a. (185 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (1042 aa)
nab2NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)
slc38a10Solute carrier family 38 member 10. (851 aa)
LOC105918304Leucine rich repeat containing 17. (445 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1050 aa)
glg1Golgi glycoprotein 1b. (994 aa)
ENSFHEP00000026670Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (127 aa)
LOC105935060MADS-box domain-containing protein. (497 aa)
trim45Tripartite motif containing 45. (582 aa)
pex7Peroxisomal biogenesis factor 7. (324 aa)
ENSFHEP00000028182Bromo domain-containing protein. (84 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
LOC105918293ATPase H+ transporting accessory protein 1b. (447 aa)
LOC105923080Uncharacterized protein. (321 aa)
LOC105929389FAM20C golgi associated secretory pathway kinase. (553 aa)
LOC105935996Uncharacterized protein. (185 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa)
sulf1Sulfatase 1. (1146 aa)
ankrd11Ankyrin repeat domain 11. (2834 aa)
LOC105928446Uncharacterized protein. (515 aa)
LOC105922455Extracellular sulfatase. (921 aa)
LOC105934596Semaphorin 4e; Belongs to the semaphorin family. (708 aa)
ptpn11Protein tyrosine phosphatase non-receptor type 11a. (505 aa)
ENSFHEP00000001128SH2 domain-containing protein. (65 aa)
LOC105940353Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (352 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (20%) [HD]