(25 nodes) Transmembrane receptor protein serine/threonine kinase binding network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105933996	UPF0577-like protein. (1019 aa)
	bmp8a	Bone morphogenetic protein 8a. (435 aa)
	LOC105926907	Southpaw. (409 aa)
	ENSFHEP00000032057	Uncharacterized protein. (959 aa)
	bmp15	Bone morphogenetic protein 15. (440 aa)
	bmp5	Bone morphogenetic protein 5. (465 aa)
	LOC105939807	UPF0577-like protein. (1001 aa)
	ENSFHEP00000002273	PDZ domain-containing protein. (156 aa)
	LOC105932304	Bone morphogenetic protein 7b. (427 aa)
	sav1	Salvador family WW domain containing protein 1. (401 aa)
	ENSFHEP00000002892	Uncharacterized protein. (582 aa)
	LOC105932942	Synaptojanin 2 binding protein. (145 aa)
	LOC105918450	Teratocarcinoma-derived growth factor 1. (202 aa)
	LOC105920199	TGF_BETA_2 domain-containing protein. (446 aa)
	gdf15	Bone morphogenetic protein 6. (373 aa)
	LOC105925994	Bone morphogenetic protein 7a. (393 aa)
	LOC105939150	Bone morphogenetic protein 16. (476 aa)
	LOC105935574	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
	LOC105919514	EGF-like domain-containing protein. (216 aa)
	LOC105920636	Uncharacterized protein. (362 aa)
	LOC105933301	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (718 aa)
	ENSFHEP00000010436	TGF_BETA_2 domain-containing protein. (114 aa)
	nodal	Nodal-related 2. (379 aa)
	bmp4	Bone morphogenetic protein 4. (399 aa)
	ENSFHEP00000023563	Si:ch211-163l21.8. (521 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000002273	ENSFHEP00000032057	ENSFHEP00000002273	ENSFHEP00000032057	PDZ domain-containing protein.	Uncharacterized protein.	0.560
ENSFHEP00000002273	LOC105920636	ENSFHEP00000002273	ENSFHEP00000008931	PDZ domain-containing protein.	Uncharacterized protein.	0.586
ENSFHEP00000002273	sav1	ENSFHEP00000002273	ENSFHEP00000002850	PDZ domain-containing protein.	Salvador family WW domain containing protein 1.	0.531
ENSFHEP00000010436	LOC105918450	ENSFHEP00000010436	ENSFHEP00000003486	TGF_BETA_2 domain-containing protein.	Teratocarcinoma-derived growth factor 1.	0.521
ENSFHEP00000010436	LOC105919514	ENSFHEP00000010436	ENSFHEP00000006405	TGF_BETA_2 domain-containing protein.	EGF-like domain-containing protein.	0.521
ENSFHEP00000010436	LOC105926907	ENSFHEP00000010436	ENSFHEP00000030960	TGF_BETA_2 domain-containing protein.	Southpaw.	0.899
ENSFHEP00000010436	LOC105939150	ENSFHEP00000010436	ENSFHEP00000005655	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 16.	0.517
ENSFHEP00000010436	bmp4	ENSFHEP00000010436	ENSFHEP00000017972	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.517
ENSFHEP00000010436	nodal	ENSFHEP00000010436	ENSFHEP00000011032	TGF_BETA_2 domain-containing protein.	Nodal-related 2.	0.899
ENSFHEP00000032057	ENSFHEP00000002273	ENSFHEP00000032057	ENSFHEP00000002273	Uncharacterized protein.	PDZ domain-containing protein.	0.560
ENSFHEP00000032057	sav1	ENSFHEP00000032057	ENSFHEP00000002850	Uncharacterized protein.	Salvador family WW domain containing protein 1.	0.531
LOC105918450	ENSFHEP00000010436	ENSFHEP00000003486	ENSFHEP00000010436	Teratocarcinoma-derived growth factor 1.	TGF_BETA_2 domain-containing protein.	0.521
LOC105918450	LOC105926907	ENSFHEP00000003486	ENSFHEP00000030960	Teratocarcinoma-derived growth factor 1.	Southpaw.	0.473
LOC105919514	ENSFHEP00000010436	ENSFHEP00000006405	ENSFHEP00000010436	EGF-like domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.521
LOC105919514	LOC105926907	ENSFHEP00000006405	ENSFHEP00000030960	EGF-like domain-containing protein.	Southpaw.	0.473
LOC105920199	LOC105925994	ENSFHEP00000004514	ENSFHEP00000005231	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 7a.	0.725
LOC105920199	LOC105932304	ENSFHEP00000004514	ENSFHEP00000002391	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 7b.	0.717
LOC105920199	LOC105939150	ENSFHEP00000004514	ENSFHEP00000005655	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 16.	0.729
LOC105920199	bmp4	ENSFHEP00000004514	ENSFHEP00000017972	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.742
LOC105920636	ENSFHEP00000002273	ENSFHEP00000008931	ENSFHEP00000002273	Uncharacterized protein.	PDZ domain-containing protein.	0.586