(52 nodes) Bicellular tight junction assembly network (Fundulus heteroclitus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	pak2	Non-specific serine/threonine protein kinase. (525 aa)
	LOC105919015	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	LOC105915527	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	esam	Endothelial cell adhesion molecule a. (450 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC105924010	Uncharacterized protein. (323 aa)
	pof1b	POF1B actin binding protein. (581 aa)
	afdn	Afadin, adherens junction formation factor a. (1860 aa)
	LOC105932867	Si:ch211-191a24.4. (294 aa)
	cldn19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
	ENSFHEP00000006282	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (252 aa)
	ENSFHEP00000006316	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa)
	pdcd6ip	Programmed cell death 6 interacting protein. (880 aa)
	CLDN20	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (242 aa)
	CLDN14	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (189 aa)
	LOC105933301	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (718 aa)
	LOC105930963	Claudin 23a. (286 aa)
	LOC105925330	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
	cldn7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	tbcd	Tubulin folding cofactor D. (1198 aa)
	LOC105935476	Si:busm1-52i16.2. (333 aa)
	LOC105932058	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	srf	Serum response factor b. (599 aa)
	ect2	Epithelial cell transforming 2. (888 aa)
	LOC105925165	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	ENSFHEP00000015853	Uncharacterized protein. (215 aa)
	LOC105920991	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC105924639	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC105922234	MARVEL domain containing 2b. (571 aa)
	OCLN	Occludin. (319 aa)
	LOC105917368	Occludin a. (518 aa)
	marveld2	MARVEL domain containing 2a. (592 aa)
	ENSFHEP00000019001	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (183 aa)
	ENSFHEP00000019292	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	rab13	RAB13, member RAS oncogene family. (200 aa)
	ENSFHEP00000020413	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (132 aa)
	LOC105940175	Si:dkey-237i9.8. (761 aa)
	ENSFHEP00000023608	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (120 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (162 aa)
	ENSFHEP00000023684	Uncharacterized protein. (195 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (172 aa)
	CLDN34	Claudin 34. (241 aa)
	LOC105935446	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
	LOC105930934	Par-3 family cell polarity regulator alpha, b. (1396 aa)
	LOC105935372	Non-specific serine/threonine protein kinase. (513 aa)
	PARD3	Par-3 family cell polarity regulator. (1359 aa)
	ENSFHEP00000032710	Platelet/endothelial cell adhesion molecule 1. (636 aa)
	ENSFHEP00000033709	Uncharacterized protein. (147 aa)
	LOC105915686	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa)
	ENSFHEP00000033824	Uncharacterized protein. (215 aa)
	LOC105939297	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (507 aa)
	LOC105933626	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN14	CLDN20	ENSFHEP00000008405	ENSFHEP00000007270	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.923
CLDN14	CLDN3	ENSFHEP00000008405	ENSFHEP00000023677	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.743
CLDN14	CLDN34	ENSFHEP00000008405	ENSFHEP00000028402	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 34.	0.925
CLDN14	CLDN4	ENSFHEP00000008405	ENSFHEP00000003908	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.639
CLDN14	ENSFHEP00000006282	ENSFHEP00000008405	ENSFHEP00000006282	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.912
CLDN14	ENSFHEP00000006316	ENSFHEP00000008405	ENSFHEP00000006316	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.900
CLDN14	ENSFHEP00000015853	ENSFHEP00000008405	ENSFHEP00000015853	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.896
CLDN14	ENSFHEP00000019001	ENSFHEP00000008405	ENSFHEP00000019001	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.904
CLDN14	ENSFHEP00000019292	ENSFHEP00000008405	ENSFHEP00000019292	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.904
CLDN14	ENSFHEP00000023608	ENSFHEP00000008405	ENSFHEP00000023608	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.606
CLDN14	ENSFHEP00000023684	ENSFHEP00000008405	ENSFHEP00000023684	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.639
CLDN14	ENSFHEP00000033709	ENSFHEP00000008405	ENSFHEP00000033709	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.647
CLDN14	ENSFHEP00000033824	ENSFHEP00000008405	ENSFHEP00000033824	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.905
CLDN14	LOC105915686	ENSFHEP00000008405	ENSFHEP00000033713	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.907
CLDN14	LOC105917368	ENSFHEP00000008405	ENSFHEP00000018194	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Occludin a.	0.817
CLDN14	LOC105919015	ENSFHEP00000008405	ENSFHEP00000001946	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.942
CLDN14	LOC105924639	ENSFHEP00000008405	ENSFHEP00000017098	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.639
CLDN14	LOC105925165	ENSFHEP00000008405	ENSFHEP00000015511	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.914
CLDN14	LOC105930934	ENSFHEP00000008405	ENSFHEP00000029387	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator alpha, b.	0.907
CLDN14	LOC105932058	ENSFHEP00000008405	ENSFHEP00000012977	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.930