(17 nodes) Regulation of calcineurin-NFAT signaling cascade network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	myoz2	Myozenin 2a. (281 aa)
	LOC105938215	Nuclear factor of activated T cells 5a. (1448 aa)
	myoz1	Uncharacterized protein. (337 aa)
	LOC105920803	LIM and cysteine-rich domains 1. (355 aa)
	chp1	Calcineurin-like EF-hand protein 1. (187 aa)
	sppl3	Signal peptide peptidase 3-like protein. (383 aa)
	LOC105915343	Calcineurin-like EF-hand protein 2. (194 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
	cherp	Calcium homeostasis endoplasmic reticulum protein. (819 aa)
	LOC105916552	Uncharacterized protein. (2218 aa)
	efhb	Uncharacterized protein. (580 aa)
	LOC105933891	WH1 domain-containing protein. (377 aa)
	LOC105933473	Nuclear factor of activated T cells 5b. (1333 aa)
	igf1	Insulin growth factor I-like protein. (185 aa)
	LOC105925448	Cardiomyopathy associated 5. (1648 aa)
	LOC105915643	Myozenin 2b. (172 aa)
	ENSFHEP00000034164	Uncharacterized protein. (97 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000034164	LOC105925448	ENSFHEP00000034164	ENSFHEP00000004980	Uncharacterized protein.	Cardiomyopathy associated 5.	0.417
LOC105915343	efhb	ENSFHEP00000011027	ENSFHEP00000007416	Calcineurin-like EF-hand protein 2.	Uncharacterized protein.	0.405
LOC105915643	LOC105925448	ENSFHEP00000034154	ENSFHEP00000004980	Myozenin 2b.	Cardiomyopathy associated 5.	0.417
LOC105925448	ENSFHEP00000034164	ENSFHEP00000004980	ENSFHEP00000034164	Cardiomyopathy associated 5.	Uncharacterized protein.	0.417
LOC105925448	LOC105915643	ENSFHEP00000004980	ENSFHEP00000034154	Cardiomyopathy associated 5.	Myozenin 2b.	0.417
LOC105925448	myoz1	ENSFHEP00000004980	ENSFHEP00000024912	Cardiomyopathy associated 5.	Uncharacterized protein.	0.451
LOC105925448	myoz2	ENSFHEP00000004980	ENSFHEP00000034399	Cardiomyopathy associated 5.	Myozenin 2a.	0.417
chp1	efhb	ENSFHEP00000023695	ENSFHEP00000007416	Calcineurin-like EF-hand protein 1.	Uncharacterized protein.	0.405
efhb	LOC105915343	ENSFHEP00000007416	ENSFHEP00000011027	Uncharacterized protein.	Calcineurin-like EF-hand protein 2.	0.405
efhb	chp1	ENSFHEP00000007416	ENSFHEP00000023695	Uncharacterized protein.	Calcineurin-like EF-hand protein 1.	0.405
igf1	mtor	ENSFHEP00000002734	ENSFHEP00000010587	Insulin growth factor I-like protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.437
mtor	igf1	ENSFHEP00000010587	ENSFHEP00000002734	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	Insulin growth factor I-like protein.	0.437
myoz1	LOC105925448	ENSFHEP00000024912	ENSFHEP00000004980	Uncharacterized protein.	Cardiomyopathy associated 5.	0.451
myoz2	LOC105925448	ENSFHEP00000034399	ENSFHEP00000004980	Myozenin 2a.	Cardiomyopathy associated 5.	0.417