38 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ubxn6	UBX domain protein 6. (437 aa)
	LOC105934776	Sortilin. (805 aa)
	rilp	Rab interacting lysosomal protein. (428 aa)
	LOC105928561	Lysosomal protein transmembrane 4 beta. (225 aa)
	dennd10	DENN domain containing 10. (354 aa)
	vps36	Vacuolar protein sorting 36 homolog. (328 aa)
	leprotl1	Leptin receptor overlapping transcript like 1. (134 aa)
	chmp2b	Charged multivesicular body protein 2Bb. (220 aa)
	LOC105937830	Charged multivesicular body protein 5a. (220 aa)
	leprot	Uncharacterized protein. (130 aa)
	LOC105918178	Charged multivesicular body protein 5b. (220 aa)
	chmp3	Charged multivesicular body protein 3. (220 aa)
	chmp1a	Charged multivesicular body protein 1A. (199 aa)
	ptpn23	Protein tyrosine phosphatase, non-receptor type 23, a. (1543 aa)
	ENSFHEP00000023294	Sortilin. (568 aa)
	LOC105937254	Uncharacterized protein. (218 aa)
	LOC105918978	Charged multivesicular body protein 4b. (222 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (218 aa)
	chmp7	Charged multivesicular body protein 7. (451 aa)
	TMEM50B	Transmembrane protein 50B. (158 aa)
	LOC105936423	Charged multivesicular body protein 4Bb. (221 aa)
	chmp1b	Chromatin modifying protein 1B. (199 aa)
	chmp2a	Charged multivesicular body protein 2A. (220 aa)
	snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	lyst	Lysosomal trafficking regulator. (3463 aa)
	tmem50a	Transmembrane protein 50A. (159 aa)
	pdcd6ip	Programmed cell death 6 interacting protein. (880 aa)
	LOC105929216	Spermatogenesis-associated 5 protein 1-like protein; Belongs to the AAA ATPase family. (808 aa)
	mvb12a	Uncharacterized protein. (281 aa)
	rab27b	RAB27B, member RAS oncogene family. (218 aa)
	vta1	Vesicle (multivesicular body) trafficking 1. (164 aa)
	LOC105932046	Charged multivesicular body protein 6a. (217 aa)
	LOC105939499	Charged multivesicular body protein 6. (216 aa)
	LOC105918155	Charged multivesicular body protein 4C. (231 aa)
	rab27a	RAB27A, member RAS oncogene family. (220 aa)
	vps25	Vacuolar protein sorting 25 homolog. (174 aa)
	LAPTM4B	Lysosomal protein transmembrane 4 beta. (233 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000023294	LOC105934776	ENSFHEP00000023294	ENSFHEP00000033693	Sortilin.	Sortilin.	0.925
LAPTM4B	LOC105928561	ENSFHEP00000017814	ENSFHEP00000032887	Lysosomal protein transmembrane 4 beta.	Lysosomal protein transmembrane 4 beta.	0.904
LOC105918155	LOC105918178	ENSFHEP00000013130	ENSFHEP00000027957	Charged multivesicular body protein 4C.	Charged multivesicular body protein 5b.	0.910
LOC105918155	LOC105918978	ENSFHEP00000013130	ENSFHEP00000022761	Charged multivesicular body protein 4C.	Charged multivesicular body protein 4b.	0.948
LOC105918155	LOC105932046	ENSFHEP00000013130	ENSFHEP00000011465	Charged multivesicular body protein 4C.	Charged multivesicular body protein 6a.	0.943
LOC105918155	LOC105936423	ENSFHEP00000013130	ENSFHEP00000001006	Charged multivesicular body protein 4C.	Charged multivesicular body protein 4Bb.	0.947
LOC105918155	LOC105937830	ENSFHEP00000013130	ENSFHEP00000030572	Charged multivesicular body protein 4C.	Charged multivesicular body protein 5a.	0.910
LOC105918155	LOC105939499	ENSFHEP00000013130	ENSFHEP00000012421	Charged multivesicular body protein 4C.	Charged multivesicular body protein 6.	0.943
LOC105918155	chmp1a	ENSFHEP00000013130	ENSFHEP00000026113	Charged multivesicular body protein 4C.	Charged multivesicular body protein 1A.	0.948
LOC105918155	chmp1b	ENSFHEP00000013130	ENSFHEP00000001411	Charged multivesicular body protein 4C.	Chromatin modifying protein 1B.	0.925
LOC105918155	chmp2a	ENSFHEP00000013130	ENSFHEP00000004636	Charged multivesicular body protein 4C.	Charged multivesicular body protein 2A.	0.975
LOC105918155	chmp2b	ENSFHEP00000013130	ENSFHEP00000030608	Charged multivesicular body protein 4C.	Charged multivesicular body protein 2Bb.	0.900
LOC105918155	chmp3	ENSFHEP00000013130	ENSFHEP00000026421	Charged multivesicular body protein 4C.	Charged multivesicular body protein 3.	0.980
LOC105918155	chmp7	ENSFHEP00000013130	ENSFHEP00000021471	Charged multivesicular body protein 4C.	Charged multivesicular body protein 7.	0.981
LOC105918155	mvb12a	ENSFHEP00000013130	ENSFHEP00000010443	Charged multivesicular body protein 4C.	Uncharacterized protein.	0.616
LOC105918155	pdcd6ip	ENSFHEP00000013130	ENSFHEP00000006874	Charged multivesicular body protein 4C.	Programmed cell death 6 interacting protein.	0.995
LOC105918155	ptpn23	ENSFHEP00000013130	ENSFHEP00000024134	Charged multivesicular body protein 4C.	Protein tyrosine phosphatase, non-receptor type 23, a.	0.983
LOC105918155	snf8	ENSFHEP00000013130	ENSFHEP00000004687	Charged multivesicular body protein 4C.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.913
LOC105918155	vps25	ENSFHEP00000013130	ENSFHEP00000017743	Charged multivesicular body protein 4C.	Vacuolar protein sorting 25 homolog.	0.891
LOC105918155	vps28	ENSFHEP00000013130	ENSFHEP00000022466	Charged multivesicular body protein 4C.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.787