STRINGSTRING
LOC105939150 LOC105939150 pax2 pax2 kmo kmo sim1 sim1 smo smo bmp4 bmp4 nup160 nup160 SIM1 SIM1 hs2st1 hs2st1 shh shh LOC105920529 LOC105920529 LOC105917592 LOC105917592 LOC105920554 LOC105920554 PAX2 PAX2 basp1 basp1 LOC105920824 LOC105920824 ENSFHEP00000009660 ENSFHEP00000009660 LOC105915406 LOC105915406 pkd1 pkd1 LOC105920636 LOC105920636 klhl2 klhl2 LOC105920645 LOC105920645 pax5 pax5 LOC105918838 LOC105918838 ENSFHEP00000007356 ENSFHEP00000007356 ENSFHEP00000007335 ENSFHEP00000007335 ENSFHEP00000007305 ENSFHEP00000007305 LOC105932834 LOC105932834 LOC105937994 LOC105937994 ednra ednra LOC105935574 LOC105935574 LOC105921308 LOC105921308 wnt6 wnt6 itga3 itga3 irx3 irx3 LOC105933915 LOC105933915 ENSFHEP00000002273 ENSFHEP00000002273 kank2 kank2 ahi1 ahi1 lhx1 lhx1 myo1c myo1c LOC105929601 LOC105929601 MAFB MAFB TBX2 TBX2 LOC105929348 LOC105929348 tmem59l tmem59l LOC105917264 LOC105917264 ENSFHEP00000022010 ENSFHEP00000022010 enpep enpep nup85 nup85 LOC105940175 LOC105940175 NPHS2 NPHS2 LOC105924100 LOC105924100 LOC105935688 LOC105935688 LOC105926495 LOC105926495 LOC105933547 LOC105933547 LOC105927718 LOC105927718 tcf21 tcf21 ctnnbip1 ctnnbip1 aqp1 aqp1 ENSFHEP00000026218 ENSFHEP00000026218 prkci prkci nphs1 nphs1 GREM1 GREM1 LOC105917537 LOC105917537 podxl podxl LOC105929187 LOC105929187 LOC105917840 LOC105917840 ENSFHEP00000030437 ENSFHEP00000030437 coq8b coq8b fgf2 fgf2 LOC105920356 LOC105920356 LOC105922903 LOC105922903 sulf1 sulf1 LOC105931948 LOC105931948 pax8 pax8 LOC105915787 LOC105915787 ENSFHEP00000032057 ENSFHEP00000032057 pkd2 pkd2 LOC105931314 LOC105931314 LOC105922455 LOC105922455 LOC105930247 LOC105930247 ENSFHEP00000032710 ENSFHEP00000032710 LOC105930774 LOC105930774 gdnf gdnf wt1 wt1 epcam epcam LOC105933618 LOC105933618 ENSFHEP00000034755 ENSFHEP00000034755 LOC105921341 LOC105921341
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105939150Bone morphogenetic protein 16. (476 aa)
pax2Paired box 2a. (391 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (471 aa)
sim1Uncharacterized protein. (761 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (812 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
nup160Nucleoporin 160. (1316 aa)
SIM1SIM bHLH transcription factor 1a. (737 aa)
hs2st1Heparan sulfate 2-O-sulfotransferase 1a. (359 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
LOC105920529Mothers against decapentaplegic homolog. (520 aa)
LOC105917592COMM domain-containing protein 5. (211 aa)
LOC105920554Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1069 aa)
PAX2Paired box 2b. (338 aa)
basp1Brain abundant, membrane attached signal protein 1. (213 aa)
LOC105920824Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSFHEP00000009660Leucine zipper, putative tumor suppressor 2b. (323 aa)
LOC105915406Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (561 aa)
pkd1Polycystic kidney disease 1a. (4308 aa)
LOC105920636Uncharacterized protein. (362 aa)
klhl2Kelch-like family member 2. (605 aa)
LOC105920645Phospholipase C, epsilon 1. (1814 aa)
pax5Paired box 5. (391 aa)
LOC105918838Uncharacterized protein. (417 aa)
ENSFHEP00000007356Uncharacterized protein. (63 aa)
ENSFHEP00000007335Uncharacterized protein. (65 aa)
ENSFHEP00000007305Kelch-like family member 3. (359 aa)
LOC105932834Empty spiracles homeobox 1. (232 aa)
LOC105937994Dachsous cadherin-related 1a. (3279 aa)
ednraG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (448 aa)
LOC105935574Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
LOC105921308Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (410 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
itga3Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1059 aa)
irx3Iroquois homeobox 3a. (431 aa)
LOC105933915T-box transcription factor Ta. (421 aa)
ENSFHEP00000002273PDZ domain-containing protein. (156 aa)
kank2KN motif and ankyrin repeat domains 2. (1014 aa)
ahi1Abelson helper integration site 1. (1202 aa)
lhx1LIM homeobox 1a. (407 aa)
myo1cMyosin Ic, paralog b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1104 aa)
LOC105929601WT1 transcription factor a. (430 aa)
MAFBMAF bZIP transcription factor B. (399 aa)
TBX2T-box transcription factor 2. (686 aa)
LOC105929348Myosin Ic, paralog a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (992 aa)
tmem59lTransmembrane protein 59-like. (340 aa)
LOC105917264Uncharacterized protein. (859 aa)
ENSFHEP00000022010Uncharacterized protein. (3182 aa)
enpepAminopeptidase. (960 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (654 aa)
LOC105940175Si:dkey-237i9.8. (761 aa)
NPHS2NPHS2 stomatin family member, podocin. (451 aa)
LOC105924100Uncharacterized protein. (585 aa)
LOC105935688Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
LOC105926495Heparan sulfate 2-O-sulfotransferase 1b. (357 aa)
LOC105933547Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (523 aa)
LOC105927718Iroquois homeobox 1a. (497 aa)
tcf21Transcription factor 21. (175 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (294 aa)
ENSFHEP00000026218Uncharacterized protein. (251 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1168 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (153 aa)
LOC105917537Thrombospondin, type I, domain containing 7Aa. (1602 aa)
podxlPodocalyxin. (449 aa)
LOC105929187Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
LOC105917840Odd-skipped related transcription factor 1. (271 aa)
ENSFHEP00000030437Paired domain-containing protein. (153 aa)
coq8bCoenzyme Q8B. (632 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC105920356Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
LOC105922903Dachsous cadherin-related 1b. (3282 aa)
sulf1Sulfatase 1. (1146 aa)
LOC105931948Homeobox domain-containing protein. (440 aa)
pax8Paired box 8. (387 aa)
LOC105915787Integrin linked kinase. (452 aa)
ENSFHEP00000032057Uncharacterized protein. (959 aa)
pkd2Polycystic kidney disease 2. (890 aa)
LOC105931314Leucine zipper, putative tumor suppressor family member 3b. (715 aa)
LOC105922455Extracellular sulfatase. (921 aa)
LOC105930247G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (395 aa)
ENSFHEP00000032710Platelet/endothelial cell adhesion molecule 1. (636 aa)
LOC105930774Mothers against decapentaplegic homolog. (393 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
wt1WT1 transcription factor b. (423 aa)
epcamEpithelial cell adhesion molecule. (349 aa)
LOC105933618Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)
ENSFHEP00000034755MH1 domain-containing protein. (154 aa)
LOC105921341MH2 domain-containing protein. (222 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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