STRINGSTRING
LOC105935333 LOC105935333 spred3 spred3 adamtsl2 adamtsl2 ENSFHEP00000033938 ENSFHEP00000033938 grem2 grem2 wfikkn1 wfikkn1 spry1 spry1 vwc2 vwc2 LOC105940217 LOC105940217 LOC105934603 LOC105934603 LOC105918991 LOC105918991 LOC105918990 LOC105918990 ENSFHEP00000002273 ENSFHEP00000002273 LOC105923386 LOC105923386 ENSFHEP00000002292 ENSFHEP00000002292 hspa5 hspa5 skor2 skor2 ncln ncln fst fst LOC105923947 LOC105923947 LOC105935574 LOC105935574 LOC105937995 LOC105937995 sostdc1 sostdc1 LOC105938591 LOC105938591 cav1 cav1 LOC105920636 LOC105920636 lemd3 lemd3 smurf1 smurf1 LOC105929913 LOC105929913 LOC105919410 LOC105919410 ENSFHEP00000011489 ENSFHEP00000011489 ski ski wfikkn2 wfikkn2 strap strap LOC105918680 LOC105918680 LOC105925786 LOC105925786 ENSFHEP00000013800 ENSFHEP00000013800 LOC105931477 LOC105931477 ENSFHEP00000015248 ENSFHEP00000015248 SMURF2 SMURF2 LOC105927358 LOC105927358 LOC105933693 LOC105933693 dact2 dact2 cilp cilp ctdspl2 ctdspl2 LOC105916227 LOC105916227 bcl9l bcl9l fstl3 fstl3 ENSFHEP00000019617 ENSFHEP00000019617 ENSFHEP00000019671 ENSFHEP00000019671 chrd chrd skor1 skor1 smad6 smad6 piwil2 piwil2 LOC105937002 LOC105937002 znf451 znf451 sorl1 sorl1 spart spart ENSFHEP00000021943 ENSFHEP00000021943 ENSFHEP00000022032 ENSFHEP00000022032 sfrp2 sfrp2 LOC105921450 LOC105921450 LOC105936367 LOC105936367 smad7 smad7 snx25 snx25 LOC105927641 LOC105927641 sirt1 sirt1 nog nog ENSFHEP00000026343 ENSFHEP00000026343 glg1 glg1 pbld pbld ENSFHEP00000028036 ENSFHEP00000028036 pin1 pin1 prdm16 prdm16 LOC105930441 LOC105930441 LOC105933264 LOC105933264 tnfaip6 tnfaip6 htra3 htra3 GREM1 GREM1 chrdl2 chrdl2 LOC105923080 LOC105923080 LOC105938305 LOC105938305 ENSFHEP00000032057 ENSFHEP00000032057 ENSFHEP00000032232 ENSFHEP00000032232 ldlrad4 ldlrad4 LOC105932547 LOC105932547 ENSFHEP00000033073 ENSFHEP00000033073
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105935333Negative regulator of reactive oxygen species. (681 aa)
spred3Sprouty related EVH1 domain containing 3. (519 aa)
adamtsl2ADAMTS-like 2. (836 aa)
ENSFHEP00000033938TB domain-containing protein. (111 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
wfikkn1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (589 aa)
spry1Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (357 aa)
vwc2Von Willebrand factor C domain containing 2. (251 aa)
LOC105940217Dickkopf WNT signaling pathway inhibitor 1a. (261 aa)
LOC105934603Ig-like domain-containing protein. (572 aa)
LOC105918991BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC105918990BMP and activin membrane-bound inhibitor homolog. (256 aa)
ENSFHEP00000002273PDZ domain-containing protein. (156 aa)
LOC105923386Secreted frizzled-related protein 2 like. (342 aa)
ENSFHEP00000002292c-SKI_SMAD_bind domain-containing protein. (245 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
skor2SKI family transcriptional corepressor 2. (807 aa)
nclnNicalin. (541 aa)
fstFollistatin a. (349 aa)
LOC105923947Uncharacterized protein. (353 aa)
LOC105935574Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
LOC105937995Spartin b. (576 aa)
sostdc1Sclerostin domain containing 1a. (220 aa)
LOC105938591FCP1 homology domain-containing protein. (473 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
LOC105920636Uncharacterized protein. (362 aa)
lemd3LEM domain containing 3. (836 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
LOC105929913E3 ubiquitin-protein ligase. (770 aa)
LOC105919410Elastin microfibril interfacer 1b. (1116 aa)
ENSFHEP00000011489CIDE-N domain-containing protein. (136 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (726 aa)
wfikkn2Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (568 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
LOC105918680ADAM metallopeptidase domain 17b. (476 aa)
LOC105925786Ubiquitin-like 3b. (255 aa)
ENSFHEP00000013800Gremlin 1a, DAN family BMP antagonist. (181 aa)
LOC105931477Nodal modulator. (1221 aa)
ENSFHEP00000015248Uncharacterized protein. (235 aa)
SMURF2E3 ubiquitin-protein ligase. (785 aa)
LOC105927358WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b. (577 aa)
LOC105933693V-ski avian sarcoma viral oncogene homolog b. (676 aa)
dact2Dishevelled-binding antagonist of beta-catenin 2. (848 aa)
cilpCartilage intermediate layer protein, nucleotide pyrophosphohydrolase. (1151 aa)
ctdspl2CTD small phosphatase like 2. (476 aa)
LOC105916227Family with sequence similarity 89 member B. (156 aa)
bcl9lBcl9 like. (1446 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (150 aa)
ENSFHEP00000019617Cartilage intermediate layer protein 2. (1107 aa)
ENSFHEP00000019671Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (184 aa)
chrdChordin; Belongs to the chordin family. (1031 aa)
skor1SKI family transcriptional corepressor 1b. (678 aa)
smad6Mothers against decapentaplegic homolog. (492 aa)
piwil2Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family. (1040 aa)
LOC105937002Elastin microfibril interfacer 1a. (970 aa)
znf451Zinc finger protein 451. (876 aa)
sorl1Sortilin-related receptor, L(DLR class) A repeats containing. (2130 aa)
spartSpartin a. (619 aa)
ENSFHEP00000021943Ig-like domain-containing protein. (293 aa)
ENSFHEP00000022032Noggin; Belongs to the noggin family. (210 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LOC105921450Prostate transmembrane protein, androgen induced 1. (324 aa)
LOC105936367Mothers against decapentaplegic homolog. (503 aa)
smad7Mothers against decapentaplegic homolog. (378 aa)
snx25Sorting nexin-25. (981 aa)
LOC105927641ADAM metallopeptidase domain 17a. (865 aa)
sirt1Sirtuin 1. (719 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
ENSFHEP00000026343SKI-like proto-oncogene a. (264 aa)
glg1Golgi glycoprotein 1b. (994 aa)
pbldPhenazine biosynthesis like protein domain containing. (287 aa)
ENSFHEP00000028036Von Willebrand factor C domain containing 2 like. (143 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (156 aa)
prdm16Si:ch211-263k4.2. (1163 aa)
LOC105930441Tyrosyl-DNA phosphodiesterase 2b. (325 aa)
LOC105933264Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
tnfaip6Tumor necrosis factor, alpha-induced protein 6. (268 aa)
htra3HtrA serine peptidase 3a. (446 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (153 aa)
chrdl2Chordin-like 2. (444 aa)
LOC105923080Uncharacterized protein. (321 aa)
LOC105938305CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3. (383 aa)
ENSFHEP00000032057Uncharacterized protein. (959 aa)
ENSFHEP00000032232Uncharacterized protein. (228 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (297 aa)
LOC105932547Sprouty RTK signaling antagonist 2. (347 aa)
ENSFHEP00000033073Noggin; Belongs to the noggin family. (216 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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