12 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105915402	Activating transcription factor 4a. (442 aa)
	oma1	OMA1 zinc metallopeptidase. (516 aa)
	impact	Impact RWD domain protein. (339 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (163 aa)
	LOC105919668	Transmembrane p24 trafficking protein 2. (116 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (621 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1136 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	atf4	Activating transcription factor 4b. (447 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1654 aa)
	eif2ak1	Eukaryotic translation initiation factor 2-alpha kinase 1. (663 aa)
	dele1	Uncharacterized protein. (503 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	LOC105915402	ENSFHEP00000029640	ENSFHEP00000027151	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4a.	0.583
EIF2AK4	atf4	ENSFHEP00000029640	ENSFHEP00000024312	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4b.	0.575
EIF2AK4	eif2ak1	ENSFHEP00000029640	ENSFHEP00000032780	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.926
EIF2AK4	eif2ak3	ENSFHEP00000029640	ENSFHEP00000006976	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.962
EIF2AK4	eif2s1	ENSFHEP00000029640	ENSFHEP00000022871	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.997
EIF2AK4	impact	ENSFHEP00000029640	ENSFHEP00000000388	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.548
EIF2AK4	nfe2l2	ENSFHEP00000029640	ENSFHEP00000006428	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2-like 2a.	0.956
LOC105915402	EIF2AK4	ENSFHEP00000027151	ENSFHEP00000029640	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.583
LOC105915402	atf4	ENSFHEP00000027151	ENSFHEP00000024312	Activating transcription factor 4a.	Activating transcription factor 4b.	0.951
LOC105915402	eif2ak3	ENSFHEP00000027151	ENSFHEP00000006976	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.979
LOC105915402	eif2s1	ENSFHEP00000027151	ENSFHEP00000022871	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.977
LOC105915402	nfe2l2	ENSFHEP00000027151	ENSFHEP00000006428	Activating transcription factor 4a.	Nuclear factor, erythroid 2-like 2a.	0.679
atf4	EIF2AK4	ENSFHEP00000024312	ENSFHEP00000029640	Activating transcription factor 4b.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.575
atf4	LOC105915402	ENSFHEP00000024312	ENSFHEP00000027151	Activating transcription factor 4b.	Activating transcription factor 4a.	0.951
atf4	eif2ak3	ENSFHEP00000024312	ENSFHEP00000006976	Activating transcription factor 4b.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.973
atf4	eif2s1	ENSFHEP00000024312	ENSFHEP00000022871	Activating transcription factor 4b.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.973
dele1	eif2ak1	ENSFHEP00000034732	ENSFHEP00000032780	Uncharacterized protein.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.516
dele1	oma1	ENSFHEP00000034732	ENSFHEP00000000269	Uncharacterized protein.	OMA1 zinc metallopeptidase.	0.567
eif2ak1	EIF2AK4	ENSFHEP00000032780	ENSFHEP00000029640	Eukaryotic translation initiation factor 2-alpha kinase 1.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.926
eif2ak1	dele1	ENSFHEP00000032780	ENSFHEP00000034732	Eukaryotic translation initiation factor 2-alpha kinase 1.	Uncharacterized protein.	0.516