18 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105922184	G protein-coupled receptor 37 like 1b. (520 aa)
	ENSFHEP00000033314	ANK_REP_REGION domain-containing protein. (762 aa)
	dhfr	Dihydrofolate reductase. (165 aa)
	pink1	PTEN induced kinase 1. (585 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (621 aa)
	ENSFHEP00000008024	GTP cyclohydrolase 1. (105 aa)
	trap1	TNF receptor-associated protein 1. (715 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (676 aa)
	LOC105915798	G protein-coupled receptor 37 like 1a. (539 aa)
	ENSFHEP00000016552	G protein-coupled receptor 37b. (335 aa)
	ENSFHEP00000018558	Protein kinase domain-containing protein. (516 aa)
	pawr	PRKC apoptosis WT1 regulator protein. (337 aa)
	il10	Interleukin 10. (268 aa)
	sesn1	Sestrin 1. (548 aa)
	LOC105918893	GTP cyclohydrolase 2. (221 aa)
	LOC105925555	Sestrin 2. (558 aa)
	LOC105925715	Si:zfos-80g12.1. (371 aa)
	LOC105934791	G protein-coupled receptor 37a. (562 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000008024	dhfr	ENSFHEP00000008024	ENSFHEP00000000250	GTP cyclohydrolase 1.	Dihydrofolate reductase.	0.502
ENSFHEP00000018558	ENSFHEP00000033314	ENSFHEP00000018558	ENSFHEP00000033314	Protein kinase domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.942
ENSFHEP00000018558	pink1	ENSFHEP00000018558	ENSFHEP00000006364	Protein kinase domain-containing protein.	PTEN induced kinase 1.	0.416
ENSFHEP00000033314	ENSFHEP00000018558	ENSFHEP00000033314	ENSFHEP00000018558	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.942
ENSFHEP00000033314	pink1	ENSFHEP00000033314	ENSFHEP00000006364	ANK_REP_REGION domain-containing protein.	PTEN induced kinase 1.	0.416
LOC105918893	dhfr	ENSFHEP00000024757	ENSFHEP00000000250	GTP cyclohydrolase 2.	Dihydrofolate reductase.	0.502
LOC105925555	LOC105925715	ENSFHEP00000025442	ENSFHEP00000030078	Sestrin 2.	Si:zfos-80g12.1.	0.951
LOC105925555	sesn1	ENSFHEP00000025442	ENSFHEP00000021298	Sestrin 2.	Sestrin 1.	0.954
LOC105925715	LOC105925555	ENSFHEP00000030078	ENSFHEP00000025442	Si:zfos-80g12.1.	Sestrin 2.	0.951
LOC105925715	sesn1	ENSFHEP00000030078	ENSFHEP00000021298	Si:zfos-80g12.1.	Sestrin 1.	0.947
dhfr	ENSFHEP00000008024	ENSFHEP00000000250	ENSFHEP00000008024	Dihydrofolate reductase.	GTP cyclohydrolase 1.	0.502
dhfr	LOC105918893	ENSFHEP00000000250	ENSFHEP00000024757	Dihydrofolate reductase.	GTP cyclohydrolase 2.	0.502
pink1	ENSFHEP00000018558	ENSFHEP00000006364	ENSFHEP00000018558	PTEN induced kinase 1.	Protein kinase domain-containing protein.	0.416
pink1	ENSFHEP00000033314	ENSFHEP00000006364	ENSFHEP00000033314	PTEN induced kinase 1.	ANK_REP_REGION domain-containing protein.	0.416
pink1	trap1	ENSFHEP00000006364	ENSFHEP00000009642	PTEN induced kinase 1.	TNF receptor-associated protein 1.	0.654
ripk1	trap1	ENSFHEP00000013323	ENSFHEP00000009642	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	TNF receptor-associated protein 1.	0.509
sesn1	LOC105925555	ENSFHEP00000021298	ENSFHEP00000025442	Sestrin 1.	Sestrin 2.	0.954
sesn1	LOC105925715	ENSFHEP00000021298	ENSFHEP00000030078	Sestrin 1.	Si:zfos-80g12.1.	0.947
trap1	pink1	ENSFHEP00000009642	ENSFHEP00000006364	TNF receptor-associated protein 1.	PTEN induced kinase 1.	0.654
trap1	ripk1	ENSFHEP00000009642	ENSFHEP00000013323	TNF receptor-associated protein 1.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.509