(20 nodes) Semaphorin-plexin signaling pathway involved in axon guidance network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	LOC105927402	Plexin b2b. (1844 aa)
	ENSFHEP00000032081	Plexin_cytopl domain-containing protein. (256 aa)
	LOC105934232	Plexin A1a. (1892 aa)
	LOC105934241	Plexin b1a. (2214 aa)
	ednra	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	LOC105933691	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (819 aa)
	plxna4	Plexin A4. (1915 aa)
	LOC105934167	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (703 aa)
	LOC105937131	Sema domain-containing protein. (1848 aa)
	LOC105922372	Plexin B3. (1692 aa)
	PLXNA2	Plexin A2. (1914 aa)
	ENSFHEP00000015009	Plexin_cytopl domain-containing protein. (156 aa)
	LOC105933706	Plexin b1b. (2235 aa)
	ENSFHEP00000016574	Plexin_cytopl domain-containing protein. (377 aa)
	PLXND1	Plexin-D1. (1899 aa)
	LOC105935251	Plexin A2. (1900 aa)
	LOC105923645	Endothelin 1. (218 aa)
	ENSFHEP00000030972	Sema domain-containing protein. (417 aa)
	plxna1	Sema domain-containing protein. (1889 aa)
	LOC105921308	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (410 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000015009	ENSFHEP00000016574	ENSFHEP00000015009	ENSFHEP00000016574	Plexin_cytopl domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000015009	ENSFHEP00000030972	ENSFHEP00000015009	ENSFHEP00000030972	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.900
ENSFHEP00000015009	LOC105933691	ENSFHEP00000015009	ENSFHEP00000033336	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.413
ENSFHEP00000015009	LOC105934167	ENSFHEP00000015009	ENSFHEP00000032872	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.413
ENSFHEP00000016574	ENSFHEP00000015009	ENSFHEP00000016574	ENSFHEP00000015009	Plexin_cytopl domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000016574	ENSFHEP00000030972	ENSFHEP00000016574	ENSFHEP00000030972	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.769
ENSFHEP00000016574	ENSFHEP00000032081	ENSFHEP00000016574	ENSFHEP00000032081	Plexin_cytopl domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000016574	LOC105933691	ENSFHEP00000016574	ENSFHEP00000033336	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.413
ENSFHEP00000016574	LOC105934167	ENSFHEP00000016574	ENSFHEP00000032872	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.413
ENSFHEP00000030972	ENSFHEP00000015009	ENSFHEP00000030972	ENSFHEP00000015009	Sema domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000030972	ENSFHEP00000016574	ENSFHEP00000030972	ENSFHEP00000016574	Sema domain-containing protein.	Plexin_cytopl domain-containing protein.	0.769
ENSFHEP00000030972	ENSFHEP00000032081	ENSFHEP00000030972	ENSFHEP00000032081	Sema domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000030972	LOC105933691	ENSFHEP00000030972	ENSFHEP00000033336	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.413
ENSFHEP00000030972	LOC105934167	ENSFHEP00000030972	ENSFHEP00000032872	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.413
ENSFHEP00000032081	ENSFHEP00000016574	ENSFHEP00000032081	ENSFHEP00000016574	Plexin_cytopl domain-containing protein.	Plexin_cytopl domain-containing protein.	0.900
ENSFHEP00000032081	ENSFHEP00000030972	ENSFHEP00000032081	ENSFHEP00000030972	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.900
ENSFHEP00000032081	LOC105933691	ENSFHEP00000032081	ENSFHEP00000033336	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.413
ENSFHEP00000032081	LOC105934167	ENSFHEP00000032081	ENSFHEP00000032872	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.413
LOC105921308	LOC105923645	ENSFHEP00000006082	ENSFHEP00000029605	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.997
LOC105921308	ednra	ENSFHEP00000006082	ENSFHEP00000006902	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.933