(9 nodes) Regulation of store-operated calcium entry network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	efhb	Uncharacterized protein. (580 aa)
	HOMER2	Homer scaffold protein 2. (353 aa)
	LOC105925463	Homer scaffold protein 1b. (358 aa)
	LOC105933891	WH1 domain-containing protein. (377 aa)
	slc8b1	Sodium/potassium/calcium exchanger 6, mitochondrial; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (586 aa)
	spg11	Spatacsin_C domain-containing protein. (472 aa)
	saraf	Store-operated calcium entry-associated regulatory factor. (325 aa)
	HOMER1	Homer scaffold protein 1. (418 aa)
	homer3	Homer scaffold protein 3b. (365 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HOMER1	LOC105925463	ENSFHEP00000028333	ENSFHEP00000005156	Homer scaffold protein 1.	Homer scaffold protein 1b.	0.709
HOMER1	LOC105933891	ENSFHEP00000028333	ENSFHEP00000005508	Homer scaffold protein 1.	WH1 domain-containing protein.	0.767
HOMER2	LOC105925463	ENSFHEP00000005071	ENSFHEP00000005156	Homer scaffold protein 2.	Homer scaffold protein 1b.	0.911
HOMER2	LOC105933891	ENSFHEP00000005071	ENSFHEP00000005508	Homer scaffold protein 2.	WH1 domain-containing protein.	0.910
LOC105925463	HOMER1	ENSFHEP00000005156	ENSFHEP00000028333	Homer scaffold protein 1b.	Homer scaffold protein 1.	0.709
LOC105925463	HOMER2	ENSFHEP00000005156	ENSFHEP00000005071	Homer scaffold protein 1b.	Homer scaffold protein 2.	0.911
LOC105925463	LOC105933891	ENSFHEP00000005156	ENSFHEP00000005508	Homer scaffold protein 1b.	WH1 domain-containing protein.	0.987
LOC105925463	homer3	ENSFHEP00000005156	ENSFHEP00000030712	Homer scaffold protein 1b.	Homer scaffold protein 3b.	0.621
LOC105933891	HOMER1	ENSFHEP00000005508	ENSFHEP00000028333	WH1 domain-containing protein.	Homer scaffold protein 1.	0.767
LOC105933891	HOMER2	ENSFHEP00000005508	ENSFHEP00000005071	WH1 domain-containing protein.	Homer scaffold protein 2.	0.910
LOC105933891	LOC105925463	ENSFHEP00000005508	ENSFHEP00000005156	WH1 domain-containing protein.	Homer scaffold protein 1b.	0.987
LOC105933891	homer3	ENSFHEP00000005508	ENSFHEP00000030712	WH1 domain-containing protein.	Homer scaffold protein 3b.	0.627
efhb	saraf	ENSFHEP00000007416	ENSFHEP00000023168	Uncharacterized protein.	Store-operated calcium entry-associated regulatory factor.	0.580
homer3	LOC105925463	ENSFHEP00000030712	ENSFHEP00000005156	Homer scaffold protein 3b.	Homer scaffold protein 1b.	0.621
homer3	LOC105933891	ENSFHEP00000030712	ENSFHEP00000005508	Homer scaffold protein 3b.	WH1 domain-containing protein.	0.627
saraf	efhb	ENSFHEP00000023168	ENSFHEP00000007416	Store-operated calcium entry-associated regulatory factor.	Uncharacterized protein.	0.580