STRINGSTRING
SPDEF SPDEF rap2b rap2b ENSFHEP00000031933 ENSFHEP00000031933 DIO3 DIO3 vps36 vps36 LOC105929749 LOC105929749 ldlrad4 ldlrad4 snx20 snx20 LOC105928561 LOC105928561 LOC105939437 LOC105939437 LOC105938161 LOC105938161 LOC105934776 LOC105934776 cmtm6 cmtm6 ubxn6 ubxn6 ubap1 ubap1 lamtor4 lamtor4 LOC105920057 LOC105920057 SPRYD3 SPRYD3 LOC105931776 LOC105931776 USP50 USP50 ENSFHEP00000006221 ENSFHEP00000006221 wdr53 wdr53 SNX4 SNX4 snf8 snf8 chmp2a chmp2a LOC105938047 LOC105938047 arfgap3 arfgap3 vti1b vti1b lamtor5 lamtor5 dnajc13 dnajc13 LOC105933523 LOC105933523 washc1 washc1 NSG1 NSG1 LOC105928631 LOC105928631 wdr81 wdr81 lamtor2 lamtor2 LOC105936340 LOC105936340 LOC105924331 LOC105924331 LOC105928696 LOC105928696 chmp1b chmp1b LOC105923446 LOC105923446 snx21 snx21 LOC105936423 LOC105936423 mvb12b mvb12b slc15a4 slc15a4 LOC105928844 LOC105928844 FIG4 FIG4 gripap1 gripap1 tm9sf1 tm9sf1 cftr cftr TMEM19 TMEM19 LOC110366958 LOC110366958 LOC105917092 LOC105917092 LOC105930899 LOC105930899 mvb12a mvb12a SCAMP1 SCAMP1 LOC105932087 LOC105932087 atp13a2 atp13a2 LOC105926976 LOC105926976 plekhm2 plekhm2 LOC105932046 LOC105932046 LOC105939499 LOC105939499 ENSFHEP00000012478 ENSFHEP00000012478 LOC110366401 LOC110366401 LOC105935473 LOC105935473 tbc1d5 tbc1d5 LOC105918155 LOC105918155 tmem184a tmem184a rap2c rap2c LOC105916381 LOC105916381 coro1c coro1c ankfy1 ankfy1 lamtor3 lamtor3 snx8 snx8 vps45 vps45 TMEM184B TMEM184B ENSFHEP00000015755 ENSFHEP00000015755 RAP2B RAP2B LOC105922272 LOC105922272 snx16 snx16 SCAMP2 SCAMP2 LOC105919213 LOC105919213 rlbp1 rlbp1 abhd17b abhd17b cunh9orf85 cunh9orf85 ENSFHEP00000017184 ENSFHEP00000017184 LOC105916833 LOC105916833 vps25 vps25 LAMP5 LAMP5 LOC105925659 LOC105925659 LAPTM4B LAPTM4B LOC105939895 LOC105939895 vps4a vps4a LOC105921509 LOC105921509 abcb6 abcb6 EHD2 EHD2 LOC105934209 LOC105934209 laptm4a laptm4a ABCC4 ABCC4 LOC105927592 LOC105927592 LOC105933629 LOC105933629 LOC105915510 LOC105915510 SCAMP1-2 SCAMP1-2 vps37b vps37b sorl1 sorl1 LOC105927837 LOC105927837 LOC105934047 LOC105934047 cdip1 cdip1 LOC105921450 LOC105921450 vps28 vps28 lamtor1 lamtor1 abcc10 abcc10 LOC105918978 LOC105918978 ENSFHEP00000022876 ENSFHEP00000022876 ENSFHEP00000022939 ENSFHEP00000022939 clec16a clec16a ENSFHEP00000023294 ENSFHEP00000023294 rab35 rab35 LOC105938093 LOC105938093 LOC105931765 LOC105931765 LOC105916143 LOC105916143 usp8 usp8 chmp1a chmp1a LOC105940111 LOC105940111 zfyve28 zfyve28 ENSFHEP00000026378 ENSFHEP00000026378 chmp3 chmp3 LOC105918222 LOC105918222 smarca4 smarca4 LOC105918217 LOC105918217 LOC105938593 LOC105938593 ENSFHEP00000027989 ENSFHEP00000027989 CXorf21 CXorf21 tmem175 tmem175 LOC105940026 LOC105940026 lztr1 lztr1 LOC105932716 LOC105932716 LOC105915300 LOC105915300 vps37a vps37a LOC105935467 LOC105935467 wdr91 wdr91 hgs hgs mon2 mon2 LOC105938887 LOC105938887 chmp2b chmp2b LOC105926393 LOC105926393 VPS4B VPS4B ATP13A3 ATP13A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPDEFSAM pointed domain containing ETS transcription factor. (334 aa)
rap2bRAP2B, member of RAS oncogene family. (183 aa)
ENSFHEP00000031933Ig-like domain-containing protein. (173 aa)
DIO3Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (240 aa)
vps36Vacuolar protein sorting 36 homolog. (328 aa)
LOC105929749Endophilin-A3. (372 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (297 aa)
snx20Sorting nexin 20. (290 aa)
LOC105928561Lysosomal protein transmembrane 4 beta. (225 aa)
LOC105939437Mical-like 2b. (688 aa)
LOC105938161SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1605 aa)
LOC105934776Sortilin. (805 aa)
cmtm6MARVEL domain-containing protein. (180 aa)
ubxn6UBX domain protein 6. (437 aa)
ubap1Ubiquitin associated protein 1. (454 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (162 aa)
LOC105920057LITAF domain-containing protein. (147 aa)
SPRYD3SPRY domain containing 3. (426 aa)
LOC105931776Sorting nexin 4. (418 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (336 aa)
ENSFHEP00000006221Si:dkey-3d4.3. (128 aa)
wdr53WD repeat domain 53. (387 aa)
SNX4Sorting nexin 4. (350 aa)
snf8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
chmp2aCharged multivesicular body protein 2A. (220 aa)
LOC105938047Transmembrane protein 184bb. (435 aa)
arfgap3ADP-ribosylation factor GTPase-activating protein 3. (533 aa)
vti1bVesicle transport through interaction with t-SNAREs 1B. (227 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (94 aa)
dnajc13J domain-containing protein. (2031 aa)
LOC105933523Si:ch211-157c3.4. (148 aa)
washc1WAS protein family homolog 1. (511 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
LOC105928631ATPase 13A3. (410 aa)
wdr81WD repeat domain 81. (2058 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (165 aa)
LOC105936340Retinaldehyde binding protein 1a. (247 aa)
LOC105924331Ig-like domain-containing protein. (224 aa)
LOC105928696EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (532 aa)
chmp1bChromatin modifying protein 1B. (199 aa)
LOC105923446EH domain-containing protein 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (545 aa)
snx21Sorting nexin family member 21. (418 aa)
LOC105936423Charged multivesicular body protein 4Bb. (221 aa)
mvb12bMultivesicular body subunit 12Bb. (258 aa)
slc15a4Solute carrier family 15 member 4. (588 aa)
LOC105928844Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (909 aa)
gripap1GRIP1 associated protein 1. (832 aa)
tm9sf1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (594 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1503 aa)
TMEM19Transmembrane protein 19. (342 aa)
LOC110366958Zgc:123278. (186 aa)
LOC105917092Si:ch211-202h22.8. (144 aa)
LOC105930899SPRY domain containing 3. (420 aa)
mvb12aUncharacterized protein. (281 aa)
SCAMP1Secretory carrier-associated membrane protein. (338 aa)
LOC105932087Uncharacterized protein. (509 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1165 aa)
LOC105926976Ras-related protein Rab-7b. (448 aa)
plekhm2Pleckstrin homology domain containing, family M (with RUN domain) member 2. (995 aa)
LOC105932046Charged multivesicular body protein 6a. (217 aa)
LOC105939499Charged multivesicular body protein 6. (216 aa)
ENSFHEP00000012478LITAF domain-containing protein. (149 aa)
LOC110366401LITAF domain-containing protein. (140 aa)
LOC105935473Uncharacterized protein. (1306 aa)
tbc1d5TBC1 domain family, member 5. (870 aa)
LOC105918155Charged multivesicular body protein 4C. (231 aa)
tmem184aTransmembrane protein 184a. (424 aa)
rap2cRAP2C, member of RAS oncogene family. (183 aa)
LOC105916381Secretory carrier-associated membrane protein. (339 aa)
coro1cCoronin; Belongs to the WD repeat coronin family. (473 aa)
ankfy1Ankyrin repeat and FYVE domain containing 1. (920 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
snx8Sorting nexin 8a. (521 aa)
vps45Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (582 aa)
TMEM184BTransmembrane protein 184B. (441 aa)
ENSFHEP00000015755LITAF domain-containing protein. (143 aa)
RAP2BUncharacterized protein. (155 aa)
LOC105922272Multivesicular body subunit 12Ba. (293 aa)
snx16Sorting nexin 16. (364 aa)
SCAMP2Secretory carrier-associated membrane protein. (329 aa)
LOC105919213EH-domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
rlbp1Retinaldehyde binding protein 1b. (307 aa)
abhd17bAlpha/beta hydrolase domain-containing protein 17B. (288 aa)
cunh9orf85Zgc:101016. (210 aa)
ENSFHEP00000017184Zgc:55781. (412 aa)
LOC105916833Ubiquitin carboxyl-terminal hydrolase. (703 aa)
vps25Vacuolar protein sorting 25 homolog. (174 aa)
LAMP5Lysosomal associated membrane protein family member 5. (274 aa)
LOC105925659Ubiquitin associated protein 1 like. (305 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (233 aa)
LOC105939895Si:ch211-11k18.4. (451 aa)
vps4aVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (436 aa)
LOC105921509Ras-related protein Rap-2c. (247 aa)
abcb6ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (854 aa)
EHD2EH-domain containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (540 aa)
LOC105934209Alpha/beta hydrolase domain-containing protein 17A. (361 aa)
laptm4aLysosomal protein transmembrane 4 alpha. (253 aa)
ABCC4ATP binding cassette subfamily C member 4. (1251 aa)
LOC105927592Si:ch211-284f22.3. (305 aa)
LOC105933629Uncharacterized protein. (183 aa)
LOC105915510Cytochrome b561 family, member A3a. (304 aa)
SCAMP1-2Secretory carrier-associated membrane protein. (347 aa)
vps37bZgc:114173. (283 aa)
sorl1Sortilin-related receptor, L(DLR class) A repeats containing. (2130 aa)
LOC105927837Alpha/beta hydrolase domain-containing protein 17A. (321 aa)
LOC105934047LITAF domain-containing protein. (126 aa)
cdip1Cell death-inducing p53 target 1. (223 aa)
LOC105921450Prostate transmembrane protein, androgen induced 1. (324 aa)
vps28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (218 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
abcc10ATP-binding cassette, sub-family C (CFTR/MRP), member 10. (1596 aa)
LOC105918978Charged multivesicular body protein 4b. (222 aa)
ENSFHEP00000022876VPS37 C-terminal domain-containing protein. (282 aa)
ENSFHEP00000022939Uncharacterized protein. (177 aa)
clec16aC-type lectin domain containing 16A. (935 aa)
ENSFHEP00000023294Sortilin. (568 aa)
rab35RAB35, member RAS oncogene family b. (201 aa)
LOC105938093EH-domain containing 4. (499 aa)
LOC105931765Sortilin. (823 aa)
LOC105916143Transcription activator BRG1. (1666 aa)
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1076 aa)
chmp1aCharged multivesicular body protein 1A. (199 aa)
LOC105940111Melanoregulin. (222 aa)
zfyve28Zinc finger, FYVE domain containing 28. (1006 aa)
ENSFHEP00000026378LITAF domain-containing protein. (221 aa)
chmp3Charged multivesicular body protein 3. (220 aa)
LOC105918222Tumor susceptibility 101a. (416 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1637 aa)
LOC105918217UEV domain-containing protein. (470 aa)
LOC105938593Ubiquitin associated protein 1-like a. (324 aa)
ENSFHEP00000027989Uncharacterized protein. (212 aa)
CXorf21Chromosome X open reading frame 21. (315 aa)
tmem175Transmembrane protein 175. (456 aa)
LOC105940026Lipopolysaccharide-induced tumor necrosis factor-alpha factor. (143 aa)
lztr1Leucine-zipper transcriptional regulator 1-like protein. (780 aa)
LOC105932716Zgc:91968. (237 aa)
LOC105915300Coronin; Belongs to the WD repeat coronin family. (1211 aa)
vps37aVPS37A subunit of ESCRT-I. (394 aa)
LOC105935467ATP-binding cassette, sub-family C (CFTR/MRP), member 4. (1435 aa)
wdr91WD repeat domain 91. (701 aa)
hgsHepatocyte growth factor-regulated tyrosine kinase substrate. (713 aa)
mon2MON2 homolog, regulator of endosome-to-Golgi trafficking. (1709 aa)
LOC105938887Si:dkey-16l2.16. (162 aa)
chmp2bCharged multivesicular body protein 2Bb. (220 aa)
LOC105926393Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (410 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (544 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1171 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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