(12 nodes) SMN-Sm protein complex network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (767 aa)
	LOC105926863	Survival of motor neuron 1, telomeric. (276 aa)
	SNRPG	Small nuclear ribonucleoprotein G. (138 aa)
	gemin6	Gem (nuclear organelle) associated protein 6. (184 aa)
	gemin4	Gem (nuclear organelle) associated protein 4. (1109 aa)
	gemin2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (266 aa)
	gemin8	Gem (nuclear organelle) associated protein 8. (199 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1434 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	ENSFHEP00000012172	Small nuclear ribonucleoprotein D1 polypeptide. (82 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	gemin7	Gem (nuclear organelle) associated protein 7. (128 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000012172	LOC105926863	ENSFHEP00000012172	ENSFHEP00000032171	Small nuclear ribonucleoprotein D1 polypeptide.	Survival of motor neuron 1, telomeric.	0.992
ENSFHEP00000012172	SNRPG	ENSFHEP00000012172	ENSFHEP00000028138	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein G.	0.999
ENSFHEP00000012172	ddx20	ENSFHEP00000012172	ENSFHEP00000017964	Small nuclear ribonucleoprotein D1 polypeptide.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.864
ENSFHEP00000012172	gemin2	ENSFHEP00000012172	ENSFHEP00000018796	Small nuclear ribonucleoprotein D1 polypeptide.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.997
ENSFHEP00000012172	gemin4	ENSFHEP00000012172	ENSFHEP00000018880	Small nuclear ribonucleoprotein D1 polypeptide.	Gem (nuclear organelle) associated protein 4.	0.665
ENSFHEP00000012172	gemin5	ENSFHEP00000012172	ENSFHEP00000014745	Small nuclear ribonucleoprotein D1 polypeptide.	Gem (nuclear organelle) associated protein 5.	0.840
ENSFHEP00000012172	gemin6	ENSFHEP00000012172	ENSFHEP00000021075	Small nuclear ribonucleoprotein D1 polypeptide.	Gem (nuclear organelle) associated protein 6.	0.693
ENSFHEP00000012172	gemin7	ENSFHEP00000012172	ENSFHEP00000005670	Small nuclear ribonucleoprotein D1 polypeptide.	Gem (nuclear organelle) associated protein 7.	0.724
ENSFHEP00000012172	gemin8	ENSFHEP00000012172	ENSFHEP00000017067	Small nuclear ribonucleoprotein D1 polypeptide.	Gem (nuclear organelle) associated protein 8.	0.744
ENSFHEP00000012172	snrpd3	ENSFHEP00000012172	ENSFHEP00000009518	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein Sm D3.	0.999
ENSFHEP00000012172	strap	ENSFHEP00000012172	ENSFHEP00000013041	Small nuclear ribonucleoprotein D1 polypeptide.	Serine/threonine kinase receptor associated protein.	0.471
LOC105926863	ENSFHEP00000012172	ENSFHEP00000032171	ENSFHEP00000012172	Survival of motor neuron 1, telomeric.	Small nuclear ribonucleoprotein D1 polypeptide.	0.992
LOC105926863	SNRPG	ENSFHEP00000032171	ENSFHEP00000028138	Survival of motor neuron 1, telomeric.	Small nuclear ribonucleoprotein G.	0.981
LOC105926863	ddx20	ENSFHEP00000032171	ENSFHEP00000017964	Survival of motor neuron 1, telomeric.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.998
LOC105926863	gemin2	ENSFHEP00000032171	ENSFHEP00000018796	Survival of motor neuron 1, telomeric.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.992
LOC105926863	gemin4	ENSFHEP00000032171	ENSFHEP00000018880	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 4.	0.947
LOC105926863	gemin5	ENSFHEP00000032171	ENSFHEP00000014745	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 5.	0.951
LOC105926863	gemin6	ENSFHEP00000032171	ENSFHEP00000021075	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 6.	0.724
LOC105926863	gemin7	ENSFHEP00000032171	ENSFHEP00000005670	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 7.	0.904
LOC105926863	gemin8	ENSFHEP00000032171	ENSFHEP00000017067	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 8.	0.945