(45 nodes) PAS domain network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pask	PAS domain containing serine/threonine kinase. (1149 aa)
	kcnh6	Potassium voltage-gated channel, subfamily H (eag-related), member 6a. (1173 aa)
	LOC105929497	Uncharacterized protein. (1038 aa)
	LOC105935772	Potassium voltage-gated channel, subfamily H (eag-related), member 3. (884 aa)
	LOC105927788	Neuronal PAS domain protein 2. (530 aa)
	ENSFHEP00000001843	Uncharacterized protein. (822 aa)
	LOC105916744	Uncharacterized protein. (894 aa)
	LOC105937232	Uncharacterized protein. (946 aa)
	pde8b	Phosphodiesterase. (815 aa)
	pde8a	Phosphodiesterase. (701 aa)
	LOC105937198	Potassium voltage-gated channel, subfamily H (eag-related), member 1a. (964 aa)
	LOC105935564	Aryl hydrocarbon receptor nuclear translocator-like 2. (521 aa)
	LOC105932156	Uncharacterized protein. (1111 aa)
	LOC105936476	Uncharacterized protein. (351 aa)
	LOC105933321	Endothelial PAS domain protein 1b. (873 aa)
	LOC105935462	Potassium channel, voltage gated eag related subfamily H, member 7. (1208 aa)
	LOC105932731	Potassium voltage-gated channel, subfamily H (eag-related), member 4a. (1104 aa)
	LOC105917026	Uncharacterized protein. (811 aa)
	LOC105916972	Uncharacterized protein. (603 aa)
	LOC105939970	Potassium voltage-gated channel, subfamily H (eag-related), member 4b. (871 aa)
	ahrr	Aryl hydrocarbon receptor repressor. (680 aa)
	NCOA3	Nuclear receptor coactivator 3. (1489 aa)
	LOC105922411	Nuclear receptor coactivator 3. (1519 aa)
	SIM1	SIM bHLH transcription factor 1a. (737 aa)
	hif3alpha	Hypoxia inducible factor 1 subunit alpha, like. (603 aa)
	sim1	Uncharacterized protein. (761 aa)
	NPAS3	Neuronal PAS domain protein 3. (794 aa)
	NCOA2	Nuclear receptor coactivator. (1494 aa)
	per1	Period circadian clock 1b. (1434 aa)
	LOC105937229	BHLH domain-containing protein. (949 aa)
	LOC105916679	Period circadian clock 2. (1467 aa)
	epas1	Uncharacterized protein. (340 aa)
	hif1a	Hypoxia inducible factor 1 subunit alpha a. (754 aa)
	arnt2	Uncharacterized protein. (721 aa)
	LOC105916018	Neuronal PAS domain protein 4 like. (764 aa)
	LOC105917025	Aryl hydrocarbon receptor 2b. (913 aa)
	CLOCK	Clock circadian regulator a. (809 aa)
	kcnh8	Potassium voltage-gated channel, subfamily H (eag-related), member 8. (800 aa)
	npas4	Neuronal PAS domain protein 4a. (916 aa)
	ENSFHEP00000030853	Neuronal PAS domain protein 1. (305 aa)
	ncoa2	Nuclear receptor coactivator. (1446 aa)
	PER2	Period circadian regulator 2. (1516 aa)
	LOC105934751	Period circadian clock 3. (1265 aa)
	arntl	Aryl hydrocarbon receptor nuclear translocator-like 1a. (655 aa)
	LOC105928492	Aryl hydrocarbon receptor nuclear translocator. (769 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLOCK	ENSFHEP00000030853	ENSFHEP00000029362	ENSFHEP00000030853	Clock circadian regulator a.	Neuronal PAS domain protein 1.	0.672
CLOCK	LOC105916018	ENSFHEP00000029362	ENSFHEP00000028407	Clock circadian regulator a.	Neuronal PAS domain protein 4 like.	0.787
CLOCK	LOC105916679	ENSFHEP00000029362	ENSFHEP00000024433	Clock circadian regulator a.	Period circadian clock 2.	0.789
CLOCK	LOC105916972	ENSFHEP00000029362	ENSFHEP00000012803	Clock circadian regulator a.	Uncharacterized protein.	0.869
CLOCK	LOC105917025	ENSFHEP00000029362	ENSFHEP00000028639	Clock circadian regulator a.	Aryl hydrocarbon receptor 2b.	0.733
CLOCK	LOC105917026	ENSFHEP00000029362	ENSFHEP00000011391	Clock circadian regulator a.	Uncharacterized protein.	0.671
CLOCK	LOC105933321	ENSFHEP00000029362	ENSFHEP00000010408	Clock circadian regulator a.	Endothelial PAS domain protein 1b.	0.645
CLOCK	LOC105934751	ENSFHEP00000029362	ENSFHEP00000033747	Clock circadian regulator a.	Period circadian clock 3.	0.789
CLOCK	LOC105935564	ENSFHEP00000029362	ENSFHEP00000007289	Clock circadian regulator a.	Aryl hydrocarbon receptor nuclear translocator-like 2.	0.869
CLOCK	LOC105937229	ENSFHEP00000029362	ENSFHEP00000024216	Clock circadian regulator a.	BHLH domain-containing protein.	0.671
CLOCK	LOC105937232	ENSFHEP00000029362	ENSFHEP00000004825	Clock circadian regulator a.	Uncharacterized protein.	0.671
CLOCK	NPAS3	ENSFHEP00000029362	ENSFHEP00000022151	Clock circadian regulator a.	Neuronal PAS domain protein 3.	0.672
CLOCK	PER2	ENSFHEP00000029362	ENSFHEP00000033386	Clock circadian regulator a.	Period circadian regulator 2.	0.789
CLOCK	SIM1	ENSFHEP00000029362	ENSFHEP00000017541	Clock circadian regulator a.	SIM bHLH transcription factor 1a.	0.503
CLOCK	ahrr	ENSFHEP00000029362	ENSFHEP00000015754	Clock circadian regulator a.	Aryl hydrocarbon receptor repressor.	0.671
CLOCK	arnt2	ENSFHEP00000029362	ENSFHEP00000028260	Clock circadian regulator a.	Uncharacterized protein.	0.482
CLOCK	arntl	ENSFHEP00000029362	ENSFHEP00000034150	Clock circadian regulator a.	Aryl hydrocarbon receptor nuclear translocator-like 1a.	0.869
CLOCK	epas1	ENSFHEP00000029362	ENSFHEP00000024953	Clock circadian regulator a.	Uncharacterized protein.	0.645
CLOCK	hif1a	ENSFHEP00000029362	ENSFHEP00000025544	Clock circadian regulator a.	Hypoxia inducible factor 1 subunit alpha a.	0.645
CLOCK	hif3alpha	ENSFHEP00000029362	ENSFHEP00000018459	Clock circadian regulator a.	Hypoxia inducible factor 1 subunit alpha, like.	0.645