(13 nodes) ATP-grasp fold, subdomain 1 network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105933784	Ribosomal modification protein rimK-like family member A. (419 aa)
	SYN2	Synapsin II. (561 aa)
	gart	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1014 aa)
	syn3	Uncharacterized protein. (521 aa)
	acacb	Acetyl-CoA carboxylase beta. (2298 aa)
	LOC105932288	Synapsin IIa. (467 aa)
	sucla2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
	cps1	Carbamoyl-phosphate synthase 1, mitochondrial. (1382 aa)
	pcca	Propionyl-CoA carboxylase subunit alpha. (711 aa)
	cad	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2160 aa)
	suclg2	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (448 aa)
	LOC105927771	Acetyl-CoA carboxylase alpha. (2337 aa)
	LOC105928811	Synapsin I. (449 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105927771	LOC105933784	ENSFHEP00000002430	ENSFHEP00000014641	Acetyl-CoA carboxylase alpha.	Ribosomal modification protein rimK-like family member A.	0.512
LOC105927771	acacb	ENSFHEP00000002430	ENSFHEP00000028758	Acetyl-CoA carboxylase alpha.	Acetyl-CoA carboxylase beta.	0.953
LOC105927771	cad	ENSFHEP00000002430	ENSFHEP00000009038	Acetyl-CoA carboxylase alpha.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.698
LOC105927771	cps1	ENSFHEP00000002430	ENSFHEP00000010650	Acetyl-CoA carboxylase alpha.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.698
LOC105927771	gart	ENSFHEP00000002430	ENSFHEP00000032372	Acetyl-CoA carboxylase alpha.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.944
LOC105927771	pcca	ENSFHEP00000002430	ENSFHEP00000010428	Acetyl-CoA carboxylase alpha.	Propionyl-CoA carboxylase subunit alpha.	0.839
LOC105927771	sucla2	ENSFHEP00000002430	ENSFHEP00000021813	Acetyl-CoA carboxylase alpha.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.961
LOC105927771	suclg2	ENSFHEP00000002430	ENSFHEP00000003945	Acetyl-CoA carboxylase alpha.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.963
LOC105933784	LOC105927771	ENSFHEP00000014641	ENSFHEP00000002430	Ribosomal modification protein rimK-like family member A.	Acetyl-CoA carboxylase alpha.	0.512
LOC105933784	acacb	ENSFHEP00000014641	ENSFHEP00000028758	Ribosomal modification protein rimK-like family member A.	Acetyl-CoA carboxylase beta.	0.512
LOC105933784	cad	ENSFHEP00000014641	ENSFHEP00000009038	Ribosomal modification protein rimK-like family member A.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.534
LOC105933784	cps1	ENSFHEP00000014641	ENSFHEP00000010650	Ribosomal modification protein rimK-like family member A.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.534
LOC105933784	gart	ENSFHEP00000014641	ENSFHEP00000032372	Ribosomal modification protein rimK-like family member A.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.421
LOC105933784	pcca	ENSFHEP00000014641	ENSFHEP00000010428	Ribosomal modification protein rimK-like family member A.	Propionyl-CoA carboxylase subunit alpha.	0.518
LOC105933784	sucla2	ENSFHEP00000014641	ENSFHEP00000021813	Ribosomal modification protein rimK-like family member A.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.630
LOC105933784	suclg2	ENSFHEP00000014641	ENSFHEP00000003945	Ribosomal modification protein rimK-like family member A.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.630
acacb	LOC105927771	ENSFHEP00000028758	ENSFHEP00000002430	Acetyl-CoA carboxylase beta.	Acetyl-CoA carboxylase alpha.	0.953
acacb	LOC105933784	ENSFHEP00000028758	ENSFHEP00000014641	Acetyl-CoA carboxylase beta.	Ribosomal modification protein rimK-like family member A.	0.512
acacb	cad	ENSFHEP00000028758	ENSFHEP00000009038	Acetyl-CoA carboxylase beta.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.698
acacb	cps1	ENSFHEP00000028758	ENSFHEP00000010650	Acetyl-CoA carboxylase beta.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.698