(7 nodes) Insulin, conserved site network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RLN3	Relaxin 3a. (147 aa)
	LOC105932139	Relaxin 1. (179 aa)
	LOC105918211	Insulin-like growth factor 2b. (215 aa)
	rln3	Relaxin 3b. (146 aa)
	ENSFHEP00000020440	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (55 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (116 aa)
	igf1	Insulin growth factor I-like protein. (185 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000020440	LOC105918211	ENSFHEP00000020440	ENSFHEP00000027489	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-like growth factor 2b.	0.766
ENSFHEP00000020440	igf1	ENSFHEP00000020440	ENSFHEP00000002734	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin growth factor I-like protein.	0.862
LOC105918211	ENSFHEP00000020440	ENSFHEP00000027489	ENSFHEP00000020440	Insulin-like growth factor 2b.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.766
LOC105918211	igf1	ENSFHEP00000027489	ENSFHEP00000002734	Insulin-like growth factor 2b.	Insulin growth factor I-like protein.	0.907
LOC105918211	ins	ENSFHEP00000027489	ENSFHEP00000005373	Insulin-like growth factor 2b.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.766
LOC105932139	RLN3	ENSFHEP00000028335	ENSFHEP00000030850	Relaxin 1.	Relaxin 3a.	0.911
LOC105932139	rln3	ENSFHEP00000028335	ENSFHEP00000026659	Relaxin 1.	Relaxin 3b.	0.580
RLN3	LOC105932139	ENSFHEP00000030850	ENSFHEP00000028335	Relaxin 3a.	Relaxin 1.	0.911
RLN3	rln3	ENSFHEP00000030850	ENSFHEP00000026659	Relaxin 3a.	Relaxin 3b.	0.911
igf1	ENSFHEP00000020440	ENSFHEP00000002734	ENSFHEP00000020440	Insulin growth factor I-like protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.862
igf1	LOC105918211	ENSFHEP00000002734	ENSFHEP00000027489	Insulin growth factor I-like protein.	Insulin-like growth factor 2b.	0.907
igf1	ins	ENSFHEP00000002734	ENSFHEP00000005373	Insulin growth factor I-like protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.871
ins	LOC105918211	ENSFHEP00000005373	ENSFHEP00000027489	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-like growth factor 2b.	0.766
ins	igf1	ENSFHEP00000005373	ENSFHEP00000002734	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin growth factor I-like protein.	0.871
rln3	LOC105932139	ENSFHEP00000026659	ENSFHEP00000028335	Relaxin 3b.	Relaxin 1.	0.580
rln3	RLN3	ENSFHEP00000026659	ENSFHEP00000030850	Relaxin 3b.	Relaxin 3a.	0.911