(51 nodes) Sema domain superfamily network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105930506	Sema domain-containing protein; Belongs to the semaphorin family. (627 aa)
	LOC105921467	Sema domain-containing protein. (1083 aa)
	LOC105935280	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga; Belongs to the semaphorin family. (745 aa)
	LOC105915969	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (854 aa)
	LOC105933691	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (819 aa)
	plxna4	Plexin A4. (1915 aa)
	LOC105920320	Si:dkey-49n23.1; Belongs to the semaphorin family. (419 aa)
	LOC105934167	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (703 aa)
	sema5a	Sema domain-containing protein. (1018 aa)
	LOC105934232	Plexin A1a. (1892 aa)
	LOC105920997	Sema domain-containing protein; Belongs to the semaphorin family. (773 aa)
	LOC105934241	Plexin b1a. (2214 aa)
	ENSFHEP00000030972	Sema domain-containing protein. (417 aa)
	LOC105920420	Sema domain-containing protein; Belongs to the semaphorin family. (621 aa)
	LOC105917534	Sema domain-containing protein; Belongs to the semaphorin family. (529 aa)
	sema4b	Sema domain-containing protein; Belongs to the semaphorin family. (837 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1372 aa)
	LOC105936515	Si:ch211-113g11.6; Belongs to the semaphorin family. (479 aa)
	LOC105935251	Plexin A2. (1900 aa)
	ENSFHEP00000024813	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (720 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (871 aa)
	LOC105918472	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Belongs to the semaphorin family. (1166 aa)
	PLXND1	Plexin-D1. (1899 aa)
	LOC105932351	Sema domain-containing protein; Belongs to the semaphorin family. (834 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (798 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (721 aa)
	sema6b	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (896 aa)
	SEMA4G	Semaphorin 4G; Belongs to the semaphorin family. (847 aa)
	LOC105932470	Si:ch211-129c21.1; Belongs to the semaphorin family. (807 aa)
	LOC105934230	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (831 aa)
	LOC105933677	Macrophage stimulating 1 receptor a. (1409 aa)
	SEMA6A	Semaphorin-6A; Belongs to the semaphorin family. (1005 aa)
	mst1r	Macrophage-stimulating protein receptor. (1375 aa)
	sema3b	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (801 aa)
	LOC105929127	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family. (771 aa)
	LOC105933706	Plexin b1b. (2235 aa)
	PLXNA2	Plexin A2. (1914 aa)
	sema5b	Semaphorin-5B. (1131 aa)
	LOC105922372	Plexin B3. (1692 aa)
	sema4g	Uncharacterized protein; Belongs to the semaphorin family. (810 aa)
	LOC105937131	Sema domain-containing protein. (1848 aa)
	plxna1	Sema domain-containing protein. (1889 aa)
	sema4c	Uncharacterized protein; Belongs to the semaphorin family. (863 aa)
	ENSFHEP00000005685	Semaphorin 7A; Belongs to the semaphorin family. (441 aa)
	LOC105937680	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (1074 aa)
	LOC105939740	Sema domain-containing protein; Belongs to the semaphorin family. (517 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (887 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (758 aa)
	sema6d	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like; Belongs to the semaphorin family. (1029 aa)
	LOC105934596	Semaphorin 4e; Belongs to the semaphorin family. (708 aa)
	LOC105927402	Plexin b2b. (1844 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000005685	ENSFHEP00000030972	ENSFHEP00000005685	ENSFHEP00000030972	Semaphorin 7A; Belongs to the semaphorin family.	Sema domain-containing protein.	0.699
ENSFHEP00000005685	LOC105922372	ENSFHEP00000005685	ENSFHEP00000014098	Semaphorin 7A; Belongs to the semaphorin family.	Plexin B3.	0.657
ENSFHEP00000005685	LOC105927402	ENSFHEP00000005685	ENSFHEP00000000536	Semaphorin 7A; Belongs to the semaphorin family.	Plexin b2b.	0.579
ENSFHEP00000005685	LOC105933677	ENSFHEP00000005685	ENSFHEP00000018639	Semaphorin 7A; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor a.	0.715
ENSFHEP00000005685	LOC105933706	ENSFHEP00000005685	ENSFHEP00000016191	Semaphorin 7A; Belongs to the semaphorin family.	Plexin b1b.	0.657
ENSFHEP00000005685	LOC105934232	ENSFHEP00000005685	ENSFHEP00000031940	Semaphorin 7A; Belongs to the semaphorin family.	Plexin A1a.	0.699
ENSFHEP00000005685	LOC105934241	ENSFHEP00000005685	ENSFHEP00000031815	Semaphorin 7A; Belongs to the semaphorin family.	Plexin b1a.	0.720
ENSFHEP00000005685	LOC105935251	ENSFHEP00000005685	ENSFHEP00000024981	Semaphorin 7A; Belongs to the semaphorin family.	Plexin A2.	0.699
ENSFHEP00000005685	LOC105937131	ENSFHEP00000005685	ENSFHEP00000009399	Semaphorin 7A; Belongs to the semaphorin family.	Sema domain-containing protein.	0.579
ENSFHEP00000005685	PLXNA2	ENSFHEP00000005685	ENSFHEP00000014529	Semaphorin 7A; Belongs to the semaphorin family.	Plexin A2.	0.699
ENSFHEP00000005685	PLXND1	ENSFHEP00000005685	ENSFHEP00000022625	Semaphorin 7A; Belongs to the semaphorin family.	Plexin-D1.	0.706
ENSFHEP00000005685	met	ENSFHEP00000005685	ENSFHEP00000026901	Semaphorin 7A; Belongs to the semaphorin family.	MET proto-oncogene, receptor tyrosine kinase.	0.715
ENSFHEP00000005685	mst1r	ENSFHEP00000005685	ENSFHEP00000017969	Semaphorin 7A; Belongs to the semaphorin family.	Macrophage-stimulating protein receptor.	0.715
ENSFHEP00000005685	plxna1	ENSFHEP00000005685	ENSFHEP00000006623	Semaphorin 7A; Belongs to the semaphorin family.	Sema domain-containing protein.	0.699
ENSFHEP00000005685	plxna4	ENSFHEP00000005685	ENSFHEP00000033277	Semaphorin 7A; Belongs to the semaphorin family.	Plexin A4.	0.699
ENSFHEP00000024813	ENSFHEP00000030972	ENSFHEP00000024813	ENSFHEP00000030972	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	Sema domain-containing protein.	0.661
ENSFHEP00000024813	LOC105922372	ENSFHEP00000024813	ENSFHEP00000014098	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	Plexin B3.	0.653
ENSFHEP00000024813	LOC105927402	ENSFHEP00000024813	ENSFHEP00000000536	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	Plexin b2b.	0.653
ENSFHEP00000024813	LOC105933677	ENSFHEP00000024813	ENSFHEP00000018639	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor a.	0.715
ENSFHEP00000024813	LOC105933706	ENSFHEP00000024813	ENSFHEP00000016191	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	Plexin b1b.	0.653