(22 nodes) Sm domain network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	LSM10	LSM10, U7 small nuclear RNA associated. (116 aa)
	LOC105919714	LSM14A mRNA processing body assembly factor b. (440 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (137 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (59 aa)
	lsm12	LSM12 homolog b. (196 aa)
	lsm14b	LSM family member 14B. (367 aa)
	lsm7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (112 aa)
	ENSFHEP00000024755	Sm domain-containing protein. (73 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	SNRPG	Small nuclear ribonucleoprotein G. (138 aa)
	naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit. (133 aa)
	atxn2	Ataxin 2. (1010 aa)
	snrpf	Small nuclear ribonucleoprotein polypeptide F. (114 aa)
	LSM14B	LSM family member 14B. (391 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (89 aa)
	lsm6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
	lsm1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	ENSFHEP00000012172	Small nuclear ribonucleoprotein D1 polypeptide. (82 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000012172	ENSFHEP00000024755	ENSFHEP00000012172	ENSFHEP00000024755	Small nuclear ribonucleoprotein D1 polypeptide.	Sm domain-containing protein.	0.999
ENSFHEP00000012172	LSM10	ENSFHEP00000012172	ENSFHEP00000021368	Small nuclear ribonucleoprotein D1 polypeptide.	LSM10, U7 small nuclear RNA associated.	0.635
ENSFHEP00000012172	LSM4	ENSFHEP00000012172	ENSFHEP00000014760	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.918
ENSFHEP00000012172	LSM5	ENSFHEP00000012172	ENSFHEP00000003151	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.991
ENSFHEP00000012172	SNRPG	ENSFHEP00000012172	ENSFHEP00000028138	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein G.	0.999
ENSFHEP00000012172	lsm1	ENSFHEP00000012172	ENSFHEP00000008359	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.728
ENSFHEP00000012172	lsm12	ENSFHEP00000012172	ENSFHEP00000018090	Small nuclear ribonucleoprotein D1 polypeptide.	LSM12 homolog b.	0.436
ENSFHEP00000012172	lsm2	ENSFHEP00000012172	ENSFHEP00000026650	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.975
ENSFHEP00000012172	lsm3	ENSFHEP00000012172	ENSFHEP00000009498	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.993
ENSFHEP00000012172	lsm6	ENSFHEP00000012172	ENSFHEP00000006869	Small nuclear ribonucleoprotein D1 polypeptide.	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.990
ENSFHEP00000012172	lsm7	ENSFHEP00000012172	ENSFHEP00000024644	Small nuclear ribonucleoprotein D1 polypeptide.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.992
ENSFHEP00000012172	lsm8	ENSFHEP00000012172	ENSFHEP00000012287	Small nuclear ribonucleoprotein D1 polypeptide.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.989
ENSFHEP00000012172	naa38	ENSFHEP00000012172	ENSFHEP00000031269	Small nuclear ribonucleoprotein D1 polypeptide.	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	0.948
ENSFHEP00000012172	snrpd2	ENSFHEP00000012172	ENSFHEP00000014060	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein Sm D2.	0.999
ENSFHEP00000012172	snrpd3	ENSFHEP00000012172	ENSFHEP00000009518	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein Sm D3.	0.999
ENSFHEP00000012172	snrpe	ENSFHEP00000012172	ENSFHEP00000032931	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
ENSFHEP00000012172	snrpf	ENSFHEP00000012172	ENSFHEP00000002464	Small nuclear ribonucleoprotein D1 polypeptide.	Small nuclear ribonucleoprotein polypeptide F.	0.999
ENSFHEP00000024755	ENSFHEP00000012172	ENSFHEP00000024755	ENSFHEP00000012172	Sm domain-containing protein.	Small nuclear ribonucleoprotein D1 polypeptide.	0.999
ENSFHEP00000024755	LSM10	ENSFHEP00000024755	ENSFHEP00000021368	Sm domain-containing protein.	LSM10, U7 small nuclear RNA associated.	0.973
ENSFHEP00000024755	LSM4	ENSFHEP00000024755	ENSFHEP00000014760	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.864