33 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105935862	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (287 aa)
	LOC105931778	Mitogen-activated protein kinase. (357 aa)
	LOC105918926	Kinase D-interacting substrate 220b. (1626 aa)
	LOC105926053	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (413 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (426 aa)
	LOC105936241	V-ral simian leukemia viral oncogene homolog Ba (ras related). (207 aa)
	LOC105930007	Rap guanine nucleotide exchange factor (GEF) 1b. (1097 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	ENSFHEP00000008426	NTPase, KAP family P-loop domain containing 1. (711 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (302 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	kidins220	ANK_REP_REGION domain-containing protein. (1571 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC105929835	Mitogen-activated protein kinase. (361 aa)
	ngf	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (197 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (522 aa)
	LOC105939894	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (479 aa)
	LOC105939921	Zgc:55558. (187 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (403 aa)
	LOC105926780	Uncharacterized protein. (340 aa)
	shc2	SHC (Src homology 2 domain containing) transforming protein 2. (531 aa)
	CRK	CRK proto-oncogene, adaptor protein. (319 aa)
	LOC105918998	V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
	LOC105924144	Ras-GEF domain-containing protein. (317 aa)
	SHC3	SHC adaptor protein 3. (671 aa)
	map2k1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	LOC105931725	Mitogen-activated protein kinase. (360 aa)
	LOC105933790	KAP NTPase domain-containing protein. (686 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (870 aa)
	ENSFHEP00000028107	Uncharacterized protein. (82 aa)
	LOC105934240	Mitogen-activated protein kinase. (364 aa)
	LOC105922981	Uncharacterized protein. (214 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRK	ENSFHEP00000008426	ENSFHEP00000020489	ENSFHEP00000008426	CRK proto-oncogene, adaptor protein.	NTPase, KAP family P-loop domain containing 1.	0.635
CRK	LOC105918926	ENSFHEP00000020489	ENSFHEP00000004257	CRK proto-oncogene, adaptor protein.	Kinase D-interacting substrate 220b.	0.636
CRK	LOC105926780	ENSFHEP00000020489	ENSFHEP00000020305	CRK proto-oncogene, adaptor protein.	Uncharacterized protein.	0.954
CRK	LOC105930007	ENSFHEP00000020489	ENSFHEP00000007398	CRK proto-oncogene, adaptor protein.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.992
CRK	LOC105933790	ENSFHEP00000020489	ENSFHEP00000026697	CRK proto-oncogene, adaptor protein.	KAP NTPase domain-containing protein.	0.635
CRK	LOC105935862	ENSFHEP00000020489	ENSFHEP00000034274	CRK proto-oncogene, adaptor protein.	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.509
CRK	SHC3	ENSFHEP00000020489	ENSFHEP00000023291	CRK proto-oncogene, adaptor protein.	SHC adaptor protein 3.	0.711
CRK	crkl	ENSFHEP00000020489	ENSFHEP00000010007	CRK proto-oncogene, adaptor protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.953
CRK	frs2	ENSFHEP00000020489	ENSFHEP00000017933	CRK proto-oncogene, adaptor protein.	Fibroblast growth factor receptor substrate 2b.	0.748
CRK	kidins220	ENSFHEP00000020489	ENSFHEP00000011125	CRK proto-oncogene, adaptor protein.	ANK_REP_REGION domain-containing protein.	0.636
CRK	shc2	ENSFHEP00000020489	ENSFHEP00000020405	CRK proto-oncogene, adaptor protein.	SHC (Src homology 2 domain containing) transforming protein 2.	0.595
CSDE1	ENSFHEP00000028107	ENSFHEP00000027279	ENSFHEP00000028107	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.783
CSDE1	LOC105924144	ENSFHEP00000027279	ENSFHEP00000023266	Cold shock domain containing E1, RNA-binding.	Ras-GEF domain-containing protein.	0.783
CSDE1	LOC105929835	ENSFHEP00000027279	ENSFHEP00000014625	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase.	0.494
CSDE1	LOC105930007	ENSFHEP00000027279	ENSFHEP00000007398	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.599
CSDE1	LOC105931725	ENSFHEP00000027279	ENSFHEP00000024436	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase.	0.494
CSDE1	LOC105931778	ENSFHEP00000027279	ENSFHEP00000003817	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase.	0.494
CSDE1	LOC105934240	ENSFHEP00000027279	ENSFHEP00000031777	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase.	0.494
CSDE1	LOC105939894	ENSFHEP00000027279	ENSFHEP00000018041	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.585
CSDE1	SHC3	ENSFHEP00000027279	ENSFHEP00000023291	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 3.	0.507