(39 nodes) SUMOylation of transcription factors network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105928937	Sp5 transcription factor-like. (368 aa)
	mta1	Metastasis associated 1. (704 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	hic1	Hypermethylated in cancer 1. (746 aa)
	kctd2	Potassium channel tetramerization domain containing 2. (270 aa)
	ENSFHEP00000005091	Forkhead box D1. (317 aa)
	sp5	Uncharacterized protein. (375 aa)
	MITF	Melanocyte inducing transcription factor b. (483 aa)
	hic2	Hypermethylated in cancer 2. (581 aa)
	LOC105916619	Zinc finger MIZ-type containing 2. (831 aa)
	LOC105937167	Ubiquitin-like domain-containing protein. (133 aa)
	LOC105916118	Zgc:194189. (264 aa)
	LOC105939042	Small ubiquitin like modifier 3. (158 aa)
	LOC105929937	Forkhead box protein D1. (318 aa)
	ENSFHEP00000010355	SP-RING-type domain-containing protein. (127 aa)
	zmiz1	Zinc finger MIZ-type containing 1. (1067 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (497 aa)
	sp4	Sp4 transcription factor. (766 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1253 aa)
	LOC105931343	Forkhead box D5. (351 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	LOC105919260	Transcription factor E3. (493 aa)
	LOC105934402	Melanocyte inducing transcription factor a. (417 aa)
	tfe3	Transcription factor binding to IGHM enhancer 3b. (457 aa)
	ENSFHEP00000018671	Forkhead box L2b. (276 aa)
	tfeb	Transcription factor EB. (539 aa)
	ENSFHEP00000019692	SAP domain-containing protein. (169 aa)
	LOC105938704	SP-RING-type domain-containing protein. (1141 aa)
	nfatc2ip	Nuclear factor of activated T cells 2 interacting protein. (382 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
	foxd3	Forkhead box D3. (397 aa)
	LOC105936352	Protein inhibitor of activated STAT, 1a. (572 aa)
	LOC105933585	Small ubiquitin-related modifier. (96 aa)
	SP3	Sp3a transcription factor. (699 aa)
	LOC105939045	Sp3b transcription factor. (648 aa)
	LOC105916074	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	tfap2c	Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma). (466 aa)
	LOC105916878	Zinc finger MIZ domain-containing protein 2. (886 aa)
	LOC105927843	Forkhead box D2. (368 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000010355	ENSFHEP00000019692	ENSFHEP00000010355	ENSFHEP00000019692	SP-RING-type domain-containing protein.	SAP domain-containing protein.	0.990
ENSFHEP00000010355	LOC105916074	ENSFHEP00000010355	ENSFHEP00000027147	SP-RING-type domain-containing protein.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.867
ENSFHEP00000010355	LOC105933585	ENSFHEP00000010355	ENSFHEP00000023052	SP-RING-type domain-containing protein.	Small ubiquitin-related modifier.	0.835
ENSFHEP00000010355	LOC105936352	ENSFHEP00000010355	ENSFHEP00000022604	SP-RING-type domain-containing protein.	Protein inhibitor of activated STAT, 1a.	0.749
ENSFHEP00000010355	LOC105937167	ENSFHEP00000010355	ENSFHEP00000006742	SP-RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.835
ENSFHEP00000010355	LOC105939042	ENSFHEP00000010355	ENSFHEP00000008597	SP-RING-type domain-containing protein.	Small ubiquitin like modifier 3.	0.835
ENSFHEP00000010355	kctd2	ENSFHEP00000010355	ENSFHEP00000004044	SP-RING-type domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.862
ENSFHEP00000010355	nfatc2ip	ENSFHEP00000010355	ENSFHEP00000020515	SP-RING-type domain-containing protein.	Nuclear factor of activated T cells 2 interacting protein.	0.720
ENSFHEP00000010355	pias4	ENSFHEP00000010355	ENSFHEP00000010914	SP-RING-type domain-containing protein.	Protein inhibitor of activated STAT, 4a.	0.913
ENSFHEP00000010355	sumo1	ENSFHEP00000010355	ENSFHEP00000015878	SP-RING-type domain-containing protein.	Small ubiquitin-related modifier.	0.957
ENSFHEP00000010355	sumo2	ENSFHEP00000010355	ENSFHEP00000002112	SP-RING-type domain-containing protein.	Small ubiquitin-related modifier.	0.835
ENSFHEP00000010355	tp53bp1	ENSFHEP00000010355	ENSFHEP00000015315	SP-RING-type domain-containing protein.	Tumor protein p53 binding protein, 1.	0.726
ENSFHEP00000010355	ube2i	ENSFHEP00000010355	ENSFHEP00000021039	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.867
ENSFHEP00000019692	ENSFHEP00000010355	ENSFHEP00000019692	ENSFHEP00000010355	SAP domain-containing protein.	SP-RING-type domain-containing protein.	0.990
ENSFHEP00000019692	LOC105916074	ENSFHEP00000019692	ENSFHEP00000027147	SAP domain-containing protein.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.867
ENSFHEP00000019692	LOC105933585	ENSFHEP00000019692	ENSFHEP00000023052	SAP domain-containing protein.	Small ubiquitin-related modifier.	0.902
ENSFHEP00000019692	LOC105936352	ENSFHEP00000019692	ENSFHEP00000022604	SAP domain-containing protein.	Protein inhibitor of activated STAT, 1a.	0.943
ENSFHEP00000019692	LOC105937167	ENSFHEP00000019692	ENSFHEP00000006742	SAP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.835
ENSFHEP00000019692	LOC105939042	ENSFHEP00000019692	ENSFHEP00000008597	SAP domain-containing protein.	Small ubiquitin like modifier 3.	0.842
ENSFHEP00000019692	kctd2	ENSFHEP00000019692	ENSFHEP00000004044	SAP domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.862