STRINGSTRING
fgf2 fgf2 ENSFHEP00000033800 ENSFHEP00000033800 fgf4 fgf4 ENSFHEP00000000835 ENSFHEP00000000835 LOC105939829 LOC105939829 FGF6 FGF6 fgf23 fgf23 gab1 gab1 kras kras FGF6-2 FGF6-2 LOC105920824 LOC105920824 ENSFHEP00000010372 ENSFHEP00000010372 LOC105929247 LOC105929247 LOC105933242 LOC105933242 LOC105929147 LOC105929147 LOC105925186 LOC105925186 frs2 frs2 shc1 shc1 fgf19 fgf19 LOC105931924 LOC105931924 LOC105939921 LOC105939921 ENSFHEP00000019886 ENSFHEP00000019886 plcg1 plcg1 LOC105922040 LOC105922040 SHC4 SHC4 LOC105936911 LOC105936911 LOC105935688 LOC105935688 ENSFHEP00000026670 ENSFHEP00000026670 hras hras CSDE1 CSDE1 grb2 grb2 ENSFHEP00000033024 ENSFHEP00000033024 fgf16 fgf16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ENSFHEP00000033800PH domain-containing protein. (365 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
ENSFHEP00000000835Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (259 aa)
LOC105939829Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (264 aa)
gab1GRB2-associated binding protein 1. (872 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC105920824Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSFHEP00000010372Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC105929247Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC105933242Fibroblast growth factor receptor substrate 3. (606 aa)
LOC105929147Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC105925186Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
frs2Fibroblast growth factor receptor substrate 2b. (522 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (486 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
LOC105931924Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC105939921Zgc:55558. (187 aa)
ENSFHEP00000019886Uncharacterized protein. (184 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1309 aa)
LOC105922040Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
SHC4SHC adaptor protein 4. (392 aa)
LOC105936911Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (996 aa)
LOC105935688Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
ENSFHEP00000026670Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (127 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (870 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
ENSFHEP00000033024Uncharacterized protein. (61 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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