(99 nodes) Infectious disease network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105934662	Coronin; Belongs to the WD repeat coronin family. (501 aa)
	chmp1b	Chromatin modifying protein 1B. (199 aa)
	ganab	Glucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (947 aa)
	cnbp	CCHC-type zinc finger, nucleic acid binding protein a. (166 aa)
	mpdz	Multiple PDZ domain crumbs cell polarity complex component. (1702 aa)
	LOC105938680	ANTXR cell adhesion molecule 1d. (578 aa)
	LOC105917882	Coronin; Belongs to the WD repeat coronin family. (469 aa)
	srpk1	SRSF protein kinase 1a. (644 aa)
	sigmar1	Sigma non-opioid intracellular receptor 1. (222 aa)
	rpn1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (600 aa)
	LOC105931728	SRSF protein kinase 1b. (655 aa)
	ENSFHEP00000005129	Uncharacterized protein. (287 aa)
	ENSFHEP00000005459	SEFIR domain-containing protein. (536 aa)
	ENSFHEP00000005594	PWWP domain-containing protein. (107 aa)
	ranbp1	RAN binding protein 1. (221 aa)
	LOC105917161	Uncharacterized protein. (162 aa)
	ENSFHEP00000006325	Uncharacterized protein. (88 aa)
	zdhhc1	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (361 aa)
	crbn	Cereblon. (449 aa)
	ENSFHEP00000007267	Uncharacterized protein. (148 aa)
	ipo4	Importin 4. (993 aa)
	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B. (806 aa)
	LOC105935508	La ribonucleoprotein domain family, member 1B. (1121 aa)
	LOC105924796	Coronin; Belongs to the WD repeat coronin family. (924 aa)
	LOC105919399	Interleukin 17a/f1. (152 aa)
	LOC105919398	Uncharacterized protein. (150 aa)
	LOC105930969	ANTXR cell adhesion molecule 2b. (460 aa)
	antxr2	Anthrax toxin receptor; Belongs to the ATR family. (501 aa)
	ENSFHEP00000011288	CCAAT/enhancer-binding protein. (284 aa)
	LOC105926287	Ig-like domain-containing protein. (237 aa)
	ENSFHEP00000011455	Ig-like domain-containing protein. (162 aa)
	LOC105936047	Synaptic vesicle glycoprotein 2A. (688 aa)
	stt3a	STT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
	LOC105934288	Sb:cb649. (455 aa)
	ENSFHEP00000013056	Uncharacterized protein. (87 aa)
	ENSFHEP00000013639	Uncharacterized protein. (69 aa)
	ENSFHEP00000013656	annotation not available (69 aa)
	ipo5	Karyopherin (importin) beta 3. (1094 aa)
	ENSFHEP00000034430	Uncharacterized protein. (469 aa)
	mogs	Mannosyl-oligosaccharide glucosidase. (845 aa)
	PACS1	Phosphofurin acidic cluster sorting protein 1a. (906 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (982 aa)
	LOC105939334	La ribonucleoprotein domain family, member 1. (660 aa)
	LOC105939367	Uncharacterized protein. (276 aa)
	ENSFHEP00000033026	WH2 domain-containing protein. (224 aa)
	LOC105939923	Coronin; Belongs to the WD repeat coronin family. (522 aa)
	LOC105918065	Protein kinase domain-containing protein. (894 aa)
	LOC105926231	Synaptic vesicle glycoprotein 2. (427 aa)
	rpn2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (659 aa)
	coro2b	Coronin; Belongs to the WD repeat coronin family. (527 aa)
	kpna4	Karyopherin alpha 4 (importin alpha 3). (433 aa)
	LOC105926393	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (410 aa)
	LOC105928138	PDZ domain containing 3b. (490 aa)
	LOC105919306	Uncharacterized protein. (543 aa)
	LOC105915300	Coronin; Belongs to the WD repeat coronin family. (1211 aa)
	ENSFHEP00000028618	Uncharacterized protein. (257 aa)
	LOC105920547	ETS transcription factor ELK1. (544 aa)
	kpna3	Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
	vps16	Vacuolar protein sorting 16 homolog. (705 aa)
	coro1c	Coronin; Belongs to the WD repeat coronin family. (473 aa)
	vps39	VPS39 subunit of HOPS complex. (690 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (861 aa)
	tgfbrap1	Transforming growth factor, beta receptor associated protein 1. (845 aa)
	chmp1a	Charged multivesicular body protein 1A. (199 aa)
	LOC105918848	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (333 aa)
	ENSFHEP00000025868	STT3 oligosaccharyltransferase complex catalytic subunit B. (301 aa)
	ENSFHEP00000025804	MFS domain-containing protein. (490 aa)
	LOC105915460	Regulator of calcineurin 1a. (217 aa)
	ENSFHEP00000024931	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (75 aa)
	DAD1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (78 aa)
	LOC105925435	Synaptic vesicle glycoprotein 2Ca. (734 aa)
	rcan3	Regulator of calcineurin 3. (234 aa)
	SV2C	Synaptic vesicle glycoprotein 2C. (497 aa)
	LOC105932759	Coronin; Belongs to the WD repeat coronin family. (456 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	pacs2	Phosphofurin acidic cluster sorting protein 2. (891 aa)
	mpp5	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (650 aa)
	wipf2	WH2 domain-containing protein. (457 aa)
	ENSFHEP00000021926	Uncharacterized protein. (749 aa)
	edem2	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (563 aa)
	LOC105935814	ANTXR cell adhesion molecule 1b. (534 aa)
	LOC105927307	SEFIR domain-containing protein. (561 aa)
	LOC105937422	Uncharacterized protein. (258 aa)
	acp1	LMWPc domain-containing protein. (196 aa)
	LOC105934147	Synaptic vesicle glycoprotein 2Ba. (695 aa)
	LOC105922127	Uncharacterized protein. (321 aa)
	ENSFHEP00000020297	Uncharacterized protein. (663 aa)
	il10	Interleukin 10. (268 aa)
	LOC105917348	Uncharacterized protein; Belongs to the MAGUK family. (538 aa)
	tufm	Tu translation elongation factor, mitochondrial. (432 aa)
	LOC105934096	SRSF protein kinase 3. (591 aa)
	ANTXR1	ANTXR cell adhesion molecule 1. (620 aa)
	vps33b	VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (616 aa)
	LOC105929750	Synaptic vesicle glycoprotein 2Bb. (684 aa)
	LOC105934234	Si:ch211-220i18.4; Belongs to the protein kinase superfamily. (402 aa)
	LOC105930871	ANTXR cell adhesion molecule 1c. (448 aa)
	ENSFHEP00000014528	Uncharacterized protein. (309 aa)
	LOC105927452	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (694 aa)
	LOC105922373	SRSF protein kinase 3. (929 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANTXR1	LOC105930871	ENSFHEP00000017916	ENSFHEP00000015605	ANTXR cell adhesion molecule 1.	ANTXR cell adhesion molecule 1c.	0.724
ANTXR1	LOC105930969	ENSFHEP00000017916	ENSFHEP00000010927	ANTXR cell adhesion molecule 1.	ANTXR cell adhesion molecule 2b.	0.798
ANTXR1	LOC105935814	ENSFHEP00000017916	ENSFHEP00000021733	ANTXR cell adhesion molecule 1.	ANTXR cell adhesion molecule 1b.	0.588
ANTXR1	LOC105938680	ENSFHEP00000017916	ENSFHEP00000003311	ANTXR cell adhesion molecule 1.	ANTXR cell adhesion molecule 1d.	0.724
ANTXR1	antxr2	ENSFHEP00000017916	ENSFHEP00000011230	ANTXR cell adhesion molecule 1.	Anthrax toxin receptor; Belongs to the ATR family.	0.728
DAD1	ENSFHEP00000007267	ENSFHEP00000024902	ENSFHEP00000007267	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Uncharacterized protein.	0.894
DAD1	ENSFHEP00000024931	ENSFHEP00000024902	ENSFHEP00000024931	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.514
DAD1	ENSFHEP00000025868	ENSFHEP00000024902	ENSFHEP00000025868	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	STT3 oligosaccharyltransferase complex catalytic subunit B.	0.894
DAD1	STT3B	ENSFHEP00000024902	ENSFHEP00000008614	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	STT3 oligosaccharyltransferase complex catalytic subunit B.	0.894
DAD1	mogs	ENSFHEP00000024902	ENSFHEP00000034072	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Mannosyl-oligosaccharide glucosidase.	0.797
DAD1	rpn1	ENSFHEP00000024902	ENSFHEP00000004615	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.994
DAD1	rpn2	ENSFHEP00000024902	ENSFHEP00000031268	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.996
DAD1	stt3a	ENSFHEP00000024902	ENSFHEP00000012612	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	STT3 oligosaccharyltransferase complex catalytic subunit A.	0.894
ENSFHEP00000005129	ENSFHEP00000034430	ENSFHEP00000005129	ENSFHEP00000034430	Uncharacterized protein.	Uncharacterized protein.	0.893
ENSFHEP00000005129	LOC105917348	ENSFHEP00000005129	ENSFHEP00000019674	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.976
ENSFHEP00000005129	mpdz	ENSFHEP00000005129	ENSFHEP00000002224	Uncharacterized protein.	Multiple PDZ domain crumbs cell polarity complex component.	0.909
ENSFHEP00000005129	mpp5	ENSFHEP00000005129	ENSFHEP00000022897	Uncharacterized protein.	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	0.976
ENSFHEP00000005459	LOC105917161	ENSFHEP00000005459	ENSFHEP00000006216	SEFIR domain-containing protein.	Uncharacterized protein.	0.990
ENSFHEP00000005459	LOC105919398	ENSFHEP00000005459	ENSFHEP00000010209	SEFIR domain-containing protein.	Uncharacterized protein.	0.953
ENSFHEP00000005459	LOC105919399	ENSFHEP00000005459	ENSFHEP00000010198	SEFIR domain-containing protein.	Interleukin 17a/f1.	0.990