(19 nodes) Lysine catabolism network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	aldh7a1	Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. (460 aa)
	ENSFHEP00000000608	Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
	pipox	Pipecolic acid oxidase. (363 aa)
	crym	Crystallin, mu. (322 aa)
	OGDH	Oxoglutarate dehydrogenase. (944 aa)
	ENSFHEP00000008694	Immunoresponsive gene 1, like. (500 aa)
	LOC105930097	Immunoresponsive gene 1, like. (494 aa)
	acod1	Aconitate decarboxylase 1. (435 aa)
	phykpl	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
	LOC105931436	Glutaryl-CoA dehydrogenase a. (440 aa)
	LOC105916992	Dihydrolipoamide S-succinyltransferase. (326 aa)
	aass	Aminoadipate-semialdehyde synthase. (930 aa)
	aadat	Aminoadipate aminotransferase. (434 aa)
	LOC105933240	Uncharacterized protein. (135 aa)
	DLST	Dihydrolipoamide S-succinyltransferase. (446 aa)
	hykk	Hydroxylysine kinase, tandem duplicate 1. (385 aa)
	dld	Dihydrolipoyl dehydrogenase. (514 aa)
	gcdh	Glutaryl-CoA dehydrogenase b. (440 aa)
	LOC105915617	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (977 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLST	LOC105915617	ENSFHEP00000021556	ENSFHEP00000034992	Dihydrolipoamide S-succinyltransferase.	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).	0.998
DLST	LOC105931436	ENSFHEP00000021556	ENSFHEP00000013624	Dihydrolipoamide S-succinyltransferase.	Glutaryl-CoA dehydrogenase a.	0.930
DLST	LOC105933240	ENSFHEP00000021556	ENSFHEP00000020127	Dihydrolipoamide S-succinyltransferase.	Uncharacterized protein.	0.708
DLST	OGDH	ENSFHEP00000021556	ENSFHEP00000006291	Dihydrolipoamide S-succinyltransferase.	Oxoglutarate dehydrogenase.	0.998
DLST	aadat	ENSFHEP00000021556	ENSFHEP00000019646	Dihydrolipoamide S-succinyltransferase.	Aminoadipate aminotransferase.	0.903
DLST	aldh7a1	ENSFHEP00000021556	ENSFHEP00000025355	Dihydrolipoamide S-succinyltransferase.	Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.624
DLST	dld	ENSFHEP00000021556	ENSFHEP00000026455	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoyl dehydrogenase.	0.999
DLST	gcdh	ENSFHEP00000021556	ENSFHEP00000026473	Dihydrolipoamide S-succinyltransferase.	Glutaryl-CoA dehydrogenase b.	0.935
DLST	hykk	ENSFHEP00000021556	ENSFHEP00000026051	Dihydrolipoamide S-succinyltransferase.	Hydroxylysine kinase, tandem duplicate 1.	0.530
DLST	phykpl	ENSFHEP00000021556	ENSFHEP00000011629	Dihydrolipoamide S-succinyltransferase.	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.530
ENSFHEP00000008694	LOC105915617	ENSFHEP00000008694	ENSFHEP00000034992	Immunoresponsive gene 1, like.	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).	0.495
ENSFHEP00000008694	OGDH	ENSFHEP00000008694	ENSFHEP00000006291	Immunoresponsive gene 1, like.	Oxoglutarate dehydrogenase.	0.495
ENSFHEP00000008694	acod1	ENSFHEP00000008694	ENSFHEP00000010020	Immunoresponsive gene 1, like.	Aconitate decarboxylase 1.	0.894
ENSFHEP00000008694	aldh7a1	ENSFHEP00000008694	ENSFHEP00000025355	Immunoresponsive gene 1, like.	Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.728
ENSFHEP00000008694	crym	ENSFHEP00000008694	ENSFHEP00000005643	Immunoresponsive gene 1, like.	Crystallin, mu.	0.728
ENSFHEP00000008694	dld	ENSFHEP00000008694	ENSFHEP00000026455	Immunoresponsive gene 1, like.	Dihydrolipoyl dehydrogenase.	0.652
ENSFHEP00000008694	hykk	ENSFHEP00000008694	ENSFHEP00000026051	Immunoresponsive gene 1, like.	Hydroxylysine kinase, tandem duplicate 1.	0.422
ENSFHEP00000008694	phykpl	ENSFHEP00000008694	ENSFHEP00000011629	Immunoresponsive gene 1, like.	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.621
LOC105915617	DLST	ENSFHEP00000034992	ENSFHEP00000021556	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).	Dihydrolipoamide S-succinyltransferase.	0.998
LOC105915617	ENSFHEP00000008694	ENSFHEP00000034992	ENSFHEP00000008694	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).	Immunoresponsive gene 1, like.	0.495