(10 nodes) Aminotransferase class-V network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	psat1	Phosphoserine aminotransferase. (373 aa)
	sptlc3	Serine palmitoyltransferase, long chain base subunit 3. (549 aa)
	LOC105937577	Serine--pyruvate aminotransferase. (429 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (454 aa)
	ENSFHEP00000025794	Alanine--glyoxylate and serine--pyruvate aminotransferase a. (256 aa)
	gadl1	Uncharacterized protein. (492 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (834 aa)
	sgpl1	Sphingosine-1-phosphate lyase 1. (565 aa)
	alas1	5-aminolevulinate synthase. (619 aa)
	LOC105933755	5-aminolevulinate synthase. (554 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000025794	LOC105933755	ENSFHEP00000025794	ENSFHEP00000030596	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	5-aminolevulinate synthase.	0.953
ENSFHEP00000025794	LOC105937577	ENSFHEP00000025794	ENSFHEP00000034786	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	Serine--pyruvate aminotransferase.	0.967
ENSFHEP00000025794	MOCOS	ENSFHEP00000025794	ENSFHEP00000032243	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.766
ENSFHEP00000025794	alas1	ENSFHEP00000025794	ENSFHEP00000013985	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	5-aminolevulinate synthase.	0.915
ENSFHEP00000025794	psat1	ENSFHEP00000025794	ENSFHEP00000003811	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	Phosphoserine aminotransferase.	0.875
ENSFHEP00000025794	sptlc3	ENSFHEP00000025794	ENSFHEP00000034355	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	Serine palmitoyltransferase, long chain base subunit 3.	0.953
LOC105933755	ENSFHEP00000025794	ENSFHEP00000030596	ENSFHEP00000025794	5-aminolevulinate synthase.	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	0.953
LOC105933755	LOC105937577	ENSFHEP00000030596	ENSFHEP00000034786	5-aminolevulinate synthase.	Serine--pyruvate aminotransferase.	0.953
LOC105933755	alas1	ENSFHEP00000030596	ENSFHEP00000013985	5-aminolevulinate synthase.	5-aminolevulinate synthase.	0.904
LOC105937577	ENSFHEP00000025794	ENSFHEP00000034786	ENSFHEP00000025794	Serine--pyruvate aminotransferase.	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	0.967
LOC105937577	LOC105933755	ENSFHEP00000034786	ENSFHEP00000030596	Serine--pyruvate aminotransferase.	5-aminolevulinate synthase.	0.953
LOC105937577	MOCOS	ENSFHEP00000034786	ENSFHEP00000032243	Serine--pyruvate aminotransferase.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.766
LOC105937577	alas1	ENSFHEP00000034786	ENSFHEP00000013985	Serine--pyruvate aminotransferase.	5-aminolevulinate synthase.	0.915
LOC105937577	psat1	ENSFHEP00000034786	ENSFHEP00000003811	Serine--pyruvate aminotransferase.	Phosphoserine aminotransferase.	0.875
LOC105937577	sptlc3	ENSFHEP00000034786	ENSFHEP00000034355	Serine--pyruvate aminotransferase.	Serine palmitoyltransferase, long chain base subunit 3.	0.953
MOCOS	ENSFHEP00000025794	ENSFHEP00000032243	ENSFHEP00000025794	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	0.766
MOCOS	LOC105937577	ENSFHEP00000032243	ENSFHEP00000034786	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	Serine--pyruvate aminotransferase.	0.766
MOCOS	kynu	ENSFHEP00000032243	ENSFHEP00000018994	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.756
alas1	ENSFHEP00000025794	ENSFHEP00000013985	ENSFHEP00000025794	5-aminolevulinate synthase.	Alanine--glyoxylate and serine--pyruvate aminotransferase a.	0.915
alas1	LOC105933755	ENSFHEP00000013985	ENSFHEP00000030596	5-aminolevulinate synthase.	5-aminolevulinate synthase.	0.904