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ephx1 ephx1 ndrg1 ndrg1 sod2 sod2 eef2 eef2 got1 got1 cct4 cct4 GOT1 GOT1 mccc1 mccc1 msrb2 msrb2 LOC105936842 LOC105936842 LOC105933928 LOC105933928 got2 got2 LOC105935236-2 LOC105935236-2 ENSFHEP00000006217 ENSFHEP00000006217 LOC105920747 LOC105920747 cnpy2 cnpy2 HNRNPA0 HNRNPA0 LOC105920692 LOC105920692 ctss ctss LOC105928594 LOC105928594 ppm1g ppm1g mtor mtor LOC105918759 LOC105918759 LOC105919370 LOC105919370 EEF2 EEF2 stmn2 stmn2 cct2 cct2 ephx2 ephx2 ubqln4 ubqln4 AKR1D1 AKR1D1 LOC105926386 LOC105926386 prdx4 prdx4 LOC105938334 LOC105938334 PCBP2 PCBP2 LOC105938837 LOC105938837 cct3 cct3 NPC2 NPC2 LOC105919219 LOC105919219 LOC105920913 LOC105920913 pdia6 pdia6 LOC105931403 LOC105931403 hnrnpk hnrnpk tcp1 tcp1 mccc2 mccc2 tbcb tbcb LOC105918891 LOC105918891 hnrnph1 hnrnph1 gcdh gcdh LOC105931033 LOC105931033 LOC105934408 LOC105934408 hibadh hibadh LOC105925261 LOC105925261 LOC105929182 LOC105929182 LOC105926332 LOC105926332 acad11 acad11 LOC105917320 LOC105917320 cct8 cct8 LOC105931383 LOC105931383 prdx3 prdx3 pdia3 pdia3 afmid afmid LOC105931923 LOC105931923 LOC105931408 LOC105931408 mtap mtap taldo1 taldo1 LOC105926733 LOC105926733
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ephx1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (456 aa)
ndrg1N-myc downstream regulated 1a. (389 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
eef2Tr-type G domain-containing protein. (858 aa)
got1Aspartate aminotransferase. (410 aa)
cct4T-complex protein 1 subunit delta. (535 aa)
GOT1Aspartate aminotransferase. (410 aa)
mccc1Methylcrotonoyl-CoA carboxylase 1 (alpha). (698 aa)
msrb2Methionine sulfoxide reductase B2. (198 aa)
LOC105936842Calreticulin. (422 aa)
LOC105933928Stathmin; Belongs to the stathmin family. (173 aa)
got2Aspartate aminotransferase. (428 aa)
LOC105935236-2Ubiquitin-conjugating enzyme E2 variant 1. (159 aa)
ENSFHEP00000006217Stathmin; Belongs to the stathmin family. (188 aa)
LOC105920747Enoyl-CoA delta isomerase 2. (386 aa)
cnpy2Canopy FGF signaling regulator 2. (222 aa)
HNRNPA0Heterogeneous nuclear ribonucleoprotein A0. (198 aa)
LOC105920692Heterogeneous nuclear ribonucleoprotein A0. (341 aa)
ctssCathepsin S; Belongs to the peptidase C1 family. (337 aa)
LOC105928594Poly(rC)-binding protein 2. (324 aa)
ppm1gProtein phosphatase, Mg2+/Mn2+ dependent, 1G. (561 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
LOC105918759Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (400 aa)
LOC105919370Nucleophosmin 1a. (300 aa)
EEF2Eukaryotic translation elongation factor 2. (858 aa)
stmn2Stathmin; Belongs to the stathmin family. (179 aa)
cct2Chaperonin containing TCP1, subunit 2 (beta). (488 aa)
ephx2AB hydrolase-1 domain-containing protein. (543 aa)
ubqln4Ubiquilin-4. (586 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (330 aa)
LOC1059263863-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
prdx4Peroxiredoxin 4. (261 aa)
LOC105938334Adhesion regulating molecule 1. (419 aa)
PCBP2Poly(rC) binding protein 2. (216 aa)
LOC105938837Cathepsin D; Belongs to the peptidase A1 family. (382 aa)
cct3T-complex protein 1 subunit gamma. (540 aa)
NPC2NPC intracellular cholesterol transporter 2. (149 aa)
LOC105919219Stathmin; Belongs to the stathmin family. (158 aa)
LOC105920913Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (649 aa)
pdia6Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family. (440 aa)
LOC105931403Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. (401 aa)
hnrnpkHeterogeneous nuclear ribonucleoprotein K. (452 aa)
tcp1T-complex 1. (558 aa)
mccc2Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
tbcbTubulin folding cofactor B. (247 aa)
LOC105918891Cytochrome c oxidase subunit 7A2 like. (115 aa)
hnrnph1Heterogeneous nuclear ribonucleoprotein H1. (403 aa)
gcdhGlutaryl-CoA dehydrogenase b. (440 aa)
LOC105931033Calreticulin. (417 aa)
LOC105934408Synaptotagmin binding, cytoplasmic RNA interacting protein. (635 aa)
hibadh3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (328 aa)
LOC105925261Peroxiredoxin 1. (198 aa)
LOC105929182Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC105926332Stathmin; Belongs to the stathmin family. (180 aa)
acad11Acyl-CoA dehydrogenase family, member 11. (771 aa)
LOC105917320Epididymal secretory protein E1. (149 aa)
cct8Chaperonin containing TCP1, subunit 8 (theta). (558 aa)
LOC105931383Hyaluronan binding protein 4. (355 aa)
prdx3Peroxiredoxin 3. (248 aa)
pdia3Protein disulfide-isomerase. (490 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (312 aa)
LOC105931923Nucleophosmin 1b. (299 aa)
LOC105931408Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. (397 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (340 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (338 aa)
LOC105926733Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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