STRINGSTRING
ENSFHEP00000028662 ENSFHEP00000028662 dct dct stat1 stat1 braf braf ENSFHEP00000028777 ENSFHEP00000028777 stat3 stat3 tyrp1 tyrp1 cdc6 cdc6 LOC105930101 LOC105930101 PLK1 PLK1 ENSFHEP00000005886 ENSFHEP00000005886 LOC105937170 LOC105937170 TGFBR2 TGFBR2 ENSFHEP00000009414 ENSFHEP00000009414 SRC SRC LOC105918234 LOC105918234 LOC105930058 LOC105930058 bcl2 bcl2 LOC105933186 LOC105933186 LOC105933185 LOC105933185 PTEN PTEN tert tert ENSFHEP00000027711 ENSFHEP00000027711
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSFHEP00000028662Histone H3; Belongs to the histone H3 family. (97 aa)
dctDopachrome tautomerase. (514 aa)
stat1Signal transducer and activator of transcription. (762 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (773 aa)
ENSFHEP00000028777Histone H3; Belongs to the histone H3 family. (122 aa)
stat3Signal transducer and activator of transcription. (787 aa)
tyrp1Tyrosinase related protein 1. (524 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (583 aa)
LOC105930101Histone H3; Belongs to the histone H3 family. (136 aa)
PLK1Serine/threonine-protein kinase PLK. (581 aa)
ENSFHEP00000005886Histone H3; Belongs to the histone H3 family. (90 aa)
LOC105937170Disco-interacting protein 2 homolog A. (1433 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
ENSFHEP00000009414Histone H3; Belongs to the histone H3 family. (120 aa)
SRCTyrosine-protein kinase. (548 aa)
LOC105918234Tyrosine-protein kinase. (550 aa)
LOC105930058Ras-related C3 botulinum toxin substrate 1. (192 aa)
bcl2BCL2 apoptosis regulator b. (230 aa)
LOC105933186Histone H3; Belongs to the histone H3 family. (136 aa)
LOC105933185Histone H3; Belongs to the histone H3 family. (137 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (414 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1100 aa)
ENSFHEP00000027711HEXIM P-TEFb complex subunit 1. (317 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.