STRINGSTRING
mapt mapt LOC105939576 LOC105939576 ENSFHEP00000010743 ENSFHEP00000010743 LOC105920438 LOC105920438 tgfb3 tgfb3 gpx7 gpx7 TGFB3 TGFB3 sod2 sod2 gpx8 gpx8 sod1 sod1 HDAC4 HDAC4 bdnf bdnf LOC105933078 LOC105933078 il10 il10 park7 park7 LOC105937422 LOC105937422 LOC105920398 LOC105920398 LOC105931735 LOC105931735 gba gba LOC105935657 LOC105935657 ENSFHEP00000005625 ENSFHEP00000005625 pink1 pink1 LOC105929519 LOC105929519 LOC105923776 LOC105923776 hdac5 hdac5 hdac7 hdac7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
maptMicrotubule-associated protein. (502 aa)
LOC105939576Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (488 aa)
ENSFHEP00000010743Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
LOC105920438Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (158 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1101 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (303 aa)
LOC105933078Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
il10Interleukin 10. (268 aa)
park7Parkinson protein 7. (155 aa)
LOC105937422Uncharacterized protein. (258 aa)
LOC105920398Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
LOC105931735Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (936 aa)
gbaGlucosylceramidase. (607 aa)
LOC105935657Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
ENSFHEP00000005625Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (278 aa)
pink1PTEN induced kinase 1. (585 aa)
LOC105929519Glutathione peroxidase; Belongs to the glutathione peroxidase family. (146 aa)
LOC105923776Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1134 aa)
hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1043 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.