(22 nodes) (2022) The 22nd Annual Meeting of the Rocky Mountain Virology Association. network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105930195	Sad1 and UNC84 domain containing 1. (1099 aa)
	LOC105935710	Histone H2B; Belongs to the histone H2B family. (116 aa)
	LOC105936024	Histone H2B; Belongs to the histone H2B family. (133 aa)
	ace2	Angiotensin-converting enzyme. (809 aa)
	LOC105918367	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (292 aa)
	mmp9	Matrix metalloproteinase-9. (685 aa)
	LOC105937489	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (493 aa)
	ENSFHEP00000018304	Histone H2B; Belongs to the histone H2B family. (59 aa)
	LOC105930248	Caspase-8; Belongs to the peptidase C14A family. (385 aa)
	LOC105930243	Uncharacterized protein; Belongs to the peptidase C14A family. (499 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (149 aa)
	bcl2	BCL2 apoptosis regulator b. (230 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (676 aa)
	cgas	Cyclic GMP-AMP synthase. (560 aa)
	ENSFHEP00000009577	Histone H2B; Belongs to the histone H2B family. (113 aa)
	LOC105937143	Histone H2B; Belongs to the histone H2B family. (124 aa)
	LOC105916185	Histone H2B; Belongs to the histone H2B family. (124 aa)
	ENSFHEP00000008506	Histone H2B; Belongs to the histone H2B family. (121 aa)
	LOC105926891	CD40 molecule, TNF receptor superfamily member 5. (308 aa)
	LOC105916199	Histone H2B; Belongs to the histone H2B family. (67 aa)
	LOC105918655	Uncharacterized protein; Belongs to the peptidase C14A family. (269 aa)
	kdr	Receptor protein-tyrosine kinase. (1123 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105918367	LOC105918655	ENSFHEP00000024527	ENSFHEP00000030305	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.493
LOC105918367	LOC105930243	ENSFHEP00000024527	ENSFHEP00000017119	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.969
LOC105918367	LOC105930248	ENSFHEP00000024527	ENSFHEP00000017146	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Caspase-8; Belongs to the peptidase C14A family.	0.960
LOC105918367	LOC105937489	ENSFHEP00000024527	ENSFHEP00000021267	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.625
LOC105918367	bcl2	ENSFHEP00000024527	ENSFHEP00000014796	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator b.	0.698
LOC105918367	ripk1	ENSFHEP00000024527	ENSFHEP00000013323	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.456
LOC105918655	LOC105918367	ENSFHEP00000030305	ENSFHEP00000024527	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	0.493
LOC105918655	LOC105930243	ENSFHEP00000030305	ENSFHEP00000017119	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.971
LOC105918655	LOC105930248	ENSFHEP00000030305	ENSFHEP00000017146	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase-8; Belongs to the peptidase C14A family.	0.964
LOC105918655	LOC105937489	ENSFHEP00000030305	ENSFHEP00000021267	Uncharacterized protein; Belongs to the peptidase C14A family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.625
LOC105918655	bcl2	ENSFHEP00000030305	ENSFHEP00000014796	Uncharacterized protein; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator b.	0.689
LOC105918655	ripk1	ENSFHEP00000030305	ENSFHEP00000013323	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.456
LOC105926891	mmp9	ENSFHEP00000002863	ENSFHEP00000023738	CD40 molecule, TNF receptor superfamily member 5.	Matrix metalloproteinase-9.	0.428
LOC105930195	LOC105937489	ENSFHEP00000029218	ENSFHEP00000021267	Sad1 and UNC84 domain containing 1.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.497
LOC105930243	LOC105918367	ENSFHEP00000017119	ENSFHEP00000024527	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	0.969
LOC105930243	LOC105918655	ENSFHEP00000017119	ENSFHEP00000030305	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.971
LOC105930243	LOC105930248	ENSFHEP00000017119	ENSFHEP00000017146	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase-8; Belongs to the peptidase C14A family.	0.927
LOC105930243	LOC105937489	ENSFHEP00000017119	ENSFHEP00000021267	Uncharacterized protein; Belongs to the peptidase C14A family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.684
LOC105930243	bcl2	ENSFHEP00000017119	ENSFHEP00000014796	Uncharacterized protein; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator b.	0.633
LOC105930243	ripk1	ENSFHEP00000017119	ENSFHEP00000013323	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.992