(17 nodes) Domain in receptor targeting proteins Lin-2 and Lin-7 network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mpp7	Membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7); Belongs to the MAGUK family. (532 aa)
	mpp5	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (650 aa)
	lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (224 aa)
	mpp3	Membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3); Belongs to the MAGUK family. (618 aa)
	LOC105939723	Uncharacterized protein; Belongs to the MAGUK family. (553 aa)
	mpp4	Membrane protein, palmitoylated 4-like; Belongs to the MAGUK family. (577 aa)
	LOC105939418	Membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3); Belongs to the MAGUK family. (568 aa)
	LOC105926377	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (551 aa)
	LOC105917602	Uncharacterized protein; Belongs to the MAGUK family. (531 aa)
	lin7b	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (220 aa)
	LOC105935630	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (547 aa)
	mpdz	Multiple PDZ domain crumbs cell polarity complex component. (1702 aa)
	LOC105936938	Uncharacterized protein; Belongs to the MAGUK family. (874 aa)
	LOC105921523	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (960 aa)
	lin7c	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (201 aa)
	LOC105934314	Uncharacterized protein; Belongs to the MAGUK family. (553 aa)
	CASK	Uncharacterized protein; Belongs to the MAGUK family. (897 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASK	LOC105921523	ENSFHEP00000027213	ENSFHEP00000032900	Uncharacterized protein; Belongs to the MAGUK family.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.810
CASK	LOC105936938	ENSFHEP00000027213	ENSFHEP00000001224	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.824
CASK	lin7a	ENSFHEP00000027213	ENSFHEP00000019604	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	lin7b	ENSFHEP00000027213	ENSFHEP00000009092	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	lin7c	ENSFHEP00000027213	ENSFHEP00000032456	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	mpdz	ENSFHEP00000027213	ENSFHEP00000002224	Uncharacterized protein; Belongs to the MAGUK family.	Multiple PDZ domain crumbs cell polarity complex component.	0.622
LOC105917602	LOC105939418	ENSFHEP00000010620	ENSFHEP00000014534	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3); Belongs to the MAGUK family.	0.531
LOC105917602	lin7a	ENSFHEP00000010620	ENSFHEP00000019604	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.523
LOC105917602	lin7b	ENSFHEP00000010620	ENSFHEP00000009092	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.523
LOC105917602	lin7c	ENSFHEP00000010620	ENSFHEP00000032456	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.523
LOC105917602	mpp3	ENSFHEP00000010620	ENSFHEP00000019140	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3); Belongs to the MAGUK family.	0.516
LOC105917602	mpp4	ENSFHEP00000010620	ENSFHEP00000016581	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 4-like; Belongs to the MAGUK family.	0.901
LOC105917602	mpp5	ENSFHEP00000010620	ENSFHEP00000022897	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	0.927
LOC105917602	mpp7	ENSFHEP00000010620	ENSFHEP00000022507	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7); Belongs to the MAGUK family.	0.537
LOC105921523	CASK	ENSFHEP00000032900	ENSFHEP00000027213	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.810
LOC105921523	LOC105936938	ENSFHEP00000032900	ENSFHEP00000001224	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.824
LOC105921523	lin7a	ENSFHEP00000032900	ENSFHEP00000019604	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
LOC105921523	lin7b	ENSFHEP00000032900	ENSFHEP00000009092	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
LOC105921523	lin7c	ENSFHEP00000032900	ENSFHEP00000032456	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
LOC105921523	mpdz	ENSFHEP00000032900	ENSFHEP00000002224	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Multiple PDZ domain crumbs cell polarity complex component.	0.622