(30 nodes) Lissencephaly type-1-like homology motif network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgfr1op	FGFR1 oncogene partner. (512 aa)
	maea	Macrophage erythroblast attacher. (396 aa)
	LOC105939052	Single-stranded DNA-binding protein 3. (382 aa)
	LOC105939205	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	pafah1b1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (431 aa)
	armc9	Armadillo repeat containing 9. (830 aa)
	LOC105925303	Transducin (beta)-like 1 X-linked receptor 1b. (511 aa)
	fopnl	Fgfr1op N-terminal like. (140 aa)
	rmnd5b	Required for meiotic nuclear division 5 homolog B. (391 aa)
	ssbp2	Single-stranded DNA-binding protein 2. (360 aa)
	nolc1	Nucleolar and coiled-body phosphoprotein 1. (1004 aa)
	ranbp10	RAN binding protein 10. (572 aa)
	wdr26	WD repeat domain 26b. (622 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (515 aa)
	SMU1	SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
	mkln1	Muskelin 1, intracellular mediator containing kelch motifs. (748 aa)
	LOC105933173	Uncharacterized protein. (887 aa)
	LOC105933639	Transducin beta like 1 X-linked. (513 aa)
	ENSFHEP00000019167	LisH domain-containing protein. (130 aa)
	LOC105934709	LisH domain-containing protein. (1151 aa)
	SSBP4	Single stranded DNA binding protein 4. (385 aa)
	LOC105926134	GID complex subunit 8 homolog b (S. cerevisiae). (228 aa)
	LOC105939248	LisH domain-containing protein. (1553 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1026 aa)
	LOC105927878	Single stranded DNA binding protein 3b. (383 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1558 aa)
	wdr47	WD repeat-containing protein 47. (914 aa)
	GID8	Glucose-induced degradation protein 8. (228 aa)
	katnal2	Katanin p60 ATPase-containing subunit A 2-like protein. (343 aa)
	ranbp9	RAN binding protein 9. (596 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000019167	fopnl	ENSFHEP00000019167	ENSFHEP00000030601	LisH domain-containing protein.	Fgfr1op N-terminal like.	0.575
GID8	maea	ENSFHEP00000003835	ENSFHEP00000007227	Glucose-induced degradation protein 8.	Macrophage erythroblast attacher.	0.768
GID8	mkln1	ENSFHEP00000003835	ENSFHEP00000013543	Glucose-induced degradation protein 8.	Muskelin 1, intracellular mediator containing kelch motifs.	0.733
GID8	ranbp10	ENSFHEP00000003835	ENSFHEP00000023579	Glucose-induced degradation protein 8.	RAN binding protein 10.	0.905
GID8	ranbp9	ENSFHEP00000003835	ENSFHEP00000003862	Glucose-induced degradation protein 8.	RAN binding protein 9.	0.905
GID8	rmnd5b	ENSFHEP00000003835	ENSFHEP00000025835	Glucose-induced degradation protein 8.	Required for meiotic nuclear division 5 homolog B.	0.958
GID8	wdr26	ENSFHEP00000003835	ENSFHEP00000007717	Glucose-induced degradation protein 8.	WD repeat domain 26b.	0.965
LOC105925303	LOC105933639	ENSFHEP00000031033	ENSFHEP00000018762	Transducin (beta)-like 1 X-linked receptor 1b.	Transducin beta like 1 X-linked.	0.903
LOC105926134	maea	ENSFHEP00000022305	ENSFHEP00000007227	GID complex subunit 8 homolog b (S. cerevisiae).	Macrophage erythroblast attacher.	0.767
LOC105926134	mkln1	ENSFHEP00000022305	ENSFHEP00000013543	GID complex subunit 8 homolog b (S. cerevisiae).	Muskelin 1, intracellular mediator containing kelch motifs.	0.733
LOC105926134	ranbp10	ENSFHEP00000022305	ENSFHEP00000023579	GID complex subunit 8 homolog b (S. cerevisiae).	RAN binding protein 10.	0.905
LOC105926134	ranbp9	ENSFHEP00000022305	ENSFHEP00000003862	GID complex subunit 8 homolog b (S. cerevisiae).	RAN binding protein 9.	0.905
LOC105926134	rmnd5b	ENSFHEP00000022305	ENSFHEP00000025835	GID complex subunit 8 homolog b (S. cerevisiae).	Required for meiotic nuclear division 5 homolog B.	0.958
LOC105926134	wdr26	ENSFHEP00000022305	ENSFHEP00000007717	GID complex subunit 8 homolog b (S. cerevisiae).	WD repeat domain 26b.	0.965
LOC105933639	LOC105925303	ENSFHEP00000018762	ENSFHEP00000031033	Transducin beta like 1 X-linked.	Transducin (beta)-like 1 X-linked receptor 1b.	0.903
LOC105933639	TBL1XR1	ENSFHEP00000018762	ENSFHEP00000011299	Transducin beta like 1 X-linked.	Transducin beta like 1 X-linked receptor 1.	0.903
LOC105934709	armc9	ENSFHEP00000020875	ENSFHEP00000031766	LisH domain-containing protein.	Armadillo repeat containing 9.	0.435
LOC105939205	pafah1b1	ENSFHEP00000034323	ENSFHEP00000033925	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	0.716
TBL1XR1	LOC105933639	ENSFHEP00000011299	ENSFHEP00000018762	Transducin beta like 1 X-linked receptor 1.	Transducin beta like 1 X-linked.	0.903
armc9	LOC105934709	ENSFHEP00000031766	ENSFHEP00000020875	Armadillo repeat containing 9.	LisH domain-containing protein.	0.435