(13 nodes) Frizzled/Smoothened family membrane region network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000032373	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa)
	ENSFHEP00000028343	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (617 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
	ENSFHEP00000006636	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (518 aa)
	LOC105930947	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	LOC105930358	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (577 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (812 aa)
	fzd3	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
	fzd10	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
	ENSFHEP00000022272	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
	FZD3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (719 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000006636	FZD3	ENSFHEP00000006636	ENSFHEP00000032751	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.541
ENSFHEP00000006636	fzd3	ENSFHEP00000006636	ENSFHEP00000020846	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.542
ENSFHEP00000006636	fzd4	ENSFHEP00000006636	ENSFHEP00000002534	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.573
ENSFHEP00000006636	fzd6	ENSFHEP00000006636	ENSFHEP00000026833	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.547
ENSFHEP00000022272	FZD3	ENSFHEP00000022272	ENSFHEP00000032751	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.550
ENSFHEP00000022272	fzd3	ENSFHEP00000022272	ENSFHEP00000020846	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.550
ENSFHEP00000022272	fzd6	ENSFHEP00000022272	ENSFHEP00000026833	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.550
ENSFHEP00000032373	FZD3	ENSFHEP00000032373	ENSFHEP00000032751	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSFHEP00000032373	fzd3	ENSFHEP00000032373	ENSFHEP00000020846	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSFHEP00000032373	fzd4	ENSFHEP00000032373	ENSFHEP00000002534	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.505
ENSFHEP00000032373	fzd6	ENSFHEP00000032373	ENSFHEP00000026833	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
FZD3	ENSFHEP00000006636	ENSFHEP00000032751	ENSFHEP00000006636	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.541
FZD3	ENSFHEP00000022272	ENSFHEP00000032751	ENSFHEP00000022272	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	0.550
FZD3	ENSFHEP00000032373	ENSFHEP00000032751	ENSFHEP00000032373	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
FZD3	FZD7	ENSFHEP00000032751	ENSFHEP00000000675	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.539
FZD3	LOC105930358	ENSFHEP00000032751	ENSFHEP00000013293	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
FZD3	LOC105930947	ENSFHEP00000032751	ENSFHEP00000012440	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
FZD3	fzd10	ENSFHEP00000032751	ENSFHEP00000021587	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.550
FZD3	fzd4	ENSFHEP00000032751	ENSFHEP00000002534	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.601
FZD7	FZD3	ENSFHEP00000000675	ENSFHEP00000032751	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.539