(30 nodes) Fatty acid biosynthesis network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acsl3	Long-chain-fatty-acid--CoA ligase 3. (719 aa)
	acsl5	Acyl-CoA synthetase long chain family member 5. (683 aa)
	HTD2	Hydroxyacyl-thioester dehydratase type 2. (177 aa)
	hsd17b8	Hydroxysteroid (17-beta) dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa)
	LOC105937886	AMP-binding domain-containing protein. (722 aa)
	LOC105932085	Uncharacterized protein. (573 aa)
	cbr4	Carbonyl reductase 4. (238 aa)
	LOC105934410	Zgc:113054. (606 aa)
	LOC105935926	Acyl-CoA synthetase long chain family member 3b. (709 aa)
	ACSF3	Acyl-CoA synthetase family member 3. (595 aa)
	acsbg2	Acyl-CoA synthetase bubblegum family member 2. (739 aa)
	LOC105915636	Acyl-CoA synthetase long chain family member 1a. (724 aa)
	acsl4	Acyl-CoA synthetase family member 2, mitochondrial. (712 aa)
	fasn	Coiled-coil domain containing 57. (2510 aa)
	LOC105931151	DEF6 guanine nucleotide exchange factor c. (627 aa)
	LOC105937258	AMP-binding domain-containing protein. (803 aa)
	LOC105936279	Acyl-CoA synthetase family member 2. (608 aa)
	sugct	Succinyl-CoA:glutarate-CoA transferase. (508 aa)
	acacb	Acetyl-CoA carboxylase beta. (2298 aa)
	olah	Oleoyl-ACP hydrolase. (301 aa)
	ENSFHEP00000032423	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (464 aa)
	mecr	Mitochondrial trans-2-enoyl-CoA reductase. (360 aa)
	LOC105935741	Si:dkey-61p9.11. (2102 aa)
	LOC105935746	Carrier domain-containing protein. (2070 aa)
	LOC105927771	Acetyl-CoA carboxylase alpha. (2337 aa)
	mcat	Malonyl CoA:ACP acyltransferase (mitochondrial). (376 aa)
	LOC105926829	Acyl-CoA synthetase long chain family member 2. (704 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (698 aa)
	cunh15orf41	Zgc:154061. (294 aa)
	LOC105936880	AAA domain-containing protein. (819 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSF3	ACSL1	ENSFHEP00000016721	ENSFHEP00000005093	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase long chain family member 1.	0.553
ACSF3	ENSFHEP00000032423	ENSFHEP00000016721	ENSFHEP00000032423	Acyl-CoA synthetase family member 3.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.606
ACSF3	HTD2	ENSFHEP00000016721	ENSFHEP00000009222	Acyl-CoA synthetase family member 3.	Hydroxyacyl-thioester dehydratase type 2.	0.570
ACSF3	LOC105915636	ENSFHEP00000016721	ENSFHEP00000020075	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase long chain family member 1a.	0.553
ACSF3	LOC105926829	ENSFHEP00000016721	ENSFHEP00000032578	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase long chain family member 2.	0.553
ACSF3	LOC105927771	ENSFHEP00000016721	ENSFHEP00000002430	Acyl-CoA synthetase family member 3.	Acetyl-CoA carboxylase alpha.	0.961
ACSF3	LOC105934410	ENSFHEP00000016721	ENSFHEP00000016231	Acyl-CoA synthetase family member 3.	Zgc:113054.	0.542
ACSF3	LOC105935741	ENSFHEP00000016721	ENSFHEP00000001697	Acyl-CoA synthetase family member 3.	Si:dkey-61p9.11.	0.833
ACSF3	LOC105935746	ENSFHEP00000016721	ENSFHEP00000001734	Acyl-CoA synthetase family member 3.	Carrier domain-containing protein.	0.823
ACSF3	LOC105935926	ENSFHEP00000016721	ENSFHEP00000016477	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase long chain family member 3b.	0.526
ACSF3	LOC105936880	ENSFHEP00000016721	ENSFHEP00000006061	Acyl-CoA synthetase family member 3.	AAA domain-containing protein.	0.735
ACSF3	LOC105937258	ENSFHEP00000016721	ENSFHEP00000023193	Acyl-CoA synthetase family member 3.	AMP-binding domain-containing protein.	0.553
ACSF3	LOC105937886	ENSFHEP00000016721	ENSFHEP00000011734	Acyl-CoA synthetase family member 3.	AMP-binding domain-containing protein.	0.553
ACSF3	acacb	ENSFHEP00000016721	ENSFHEP00000028758	Acyl-CoA synthetase family member 3.	Acetyl-CoA carboxylase beta.	0.961
ACSF3	acsbg2	ENSFHEP00000016721	ENSFHEP00000019750	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase bubblegum family member 2.	0.553
ACSF3	acsl3	ENSFHEP00000016721	ENSFHEP00000019064	Acyl-CoA synthetase family member 3.	Long-chain-fatty-acid--CoA ligase 3.	0.526
ACSF3	acsl4	ENSFHEP00000016721	ENSFHEP00000021910	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase family member 2, mitochondrial.	0.526
ACSF3	acsl5	ENSFHEP00000016721	ENSFHEP00000010397	Acyl-CoA synthetase family member 3.	Acyl-CoA synthetase long chain family member 5.	0.553
ACSF3	cbr4	ENSFHEP00000016721	ENSFHEP00000012114	Acyl-CoA synthetase family member 3.	Carbonyl reductase 4.	0.551
ACSF3	cunh15orf41	ENSFHEP00000016721	ENSFHEP00000033253	Acyl-CoA synthetase family member 3.	Zgc:154061.	0.509