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bckdha bckdha LOC105929498 LOC105929498 hadha hadha abat abat ENSFHEP00000001772 ENSFHEP00000001772 LOC105927771 LOC105927771 ECHDC1 ECHDC1 suclg2 suclg2 ENSFHEP00000004177 ENSFHEP00000004177 mlycd mlycd LOC105938580 LOC105938580 LOC105917704 LOC105917704 LOC105918221 LOC105918221 hibch hibch ENSFHEP00000009803 ENSFHEP00000009803 pcca pcca ENSFHEP00000011653 ENSFHEP00000011653 acox1 acox1 acat1 acat1 LOC105929819 LOC105929819 acss2 acss2 pccb pccb mcee mcee ascc3 ascc3 LOC105929060 LOC105929060 mmut mmut acss3 acss3 acat2 acat2 sucla2 sucla2 dbt dbt acads acads LOC105932248 LOC105932248 acox3 acox3 suclg1 suclg1 ENSFHEP00000025839 ENSFHEP00000025839 fam114a1 fam114a1 bckdhb bckdhb dld dld LOC105920656 LOC105920656 setd4 setd4 acacb acacb setd3 setd3 aldh6a1 aldh6a1 LOC105938845 LOC105938845 LOC105929646 LOC105929646
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
LOC105929498Acetyl-coenzyme A synthetase. (677 aa)
hadhaHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b. (695 aa)
abat4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
ENSFHEP00000001772Cocaine- and amphetamine-regulated transcript 1. (107 aa)
LOC105927771Acetyl-CoA carboxylase alpha. (2337 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (448 aa)
ENSFHEP00000004177Enoyl CoA hydratase, short chain, 1, mitochondrial. (254 aa)
mlycdMalonyl-CoA decarboxylase. (504 aa)
LOC105938580L-lactate dehydrogenase C chain. (335 aa)
LOC105917704Uncharacterized protein. (107 aa)
LOC105918221L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. LDH family. (393 aa)
hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (373 aa)
ENSFHEP00000009803ACAS_N domain-containing protein. (151 aa)
pccaPropionyl-CoA carboxylase subunit alpha. (711 aa)
ENSFHEP00000011653Acyl-CoA_ox_N domain-containing protein. (137 aa)
acox1Acyl-CoA oxidase 1, palmitoyl. (545 aa)
acat1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
LOC105929819L-lactate dehydrogenase B chain. (334 aa)
acss2Acyl-CoA synthetase short chain family member 2. (698 aa)
pccbPropionyl-CoA carboxylase subunit beta. (562 aa)
mceeMethylmalonyl CoA epimerase. (173 aa)
ascc3Activating signal cointegrator 1 complex subunit 3. (2217 aa)
LOC105929060Aldedh domain-containing protein. (526 aa)
mmutMethylmalonyl CoA mutase. (754 aa)
acss3Acyl-CoA synthetase short chain family member 3. (578 aa)
acat2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (404 aa)
acadsAcyl-CoA dehydrogenase short chain. (372 aa)
LOC105932248Acetyl-coenzyme A synthetase. (673 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (613 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (393 aa)
ENSFHEP00000025839Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. (622 aa)
fam114a1Family with sequence similarity 114 member A1. (605 aa)
bckdhb2-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (390 aa)
dldDihydrolipoyl dehydrogenase. (514 aa)
LOC105920656Ethylmalonyl-CoA decarboxylase; Belongs to the enoyl-CoA hydratase/isomerase family. (307 aa)
setd4SET domain-containing protein 4. (453 aa)
acacbAcetyl-CoA carboxylase beta. (2298 aa)
setd3Protein-histidine N-methyltransferase. (588 aa)
aldh6a1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (526 aa)
LOC105938845Cocaine-and amphetamine-regulated transcript protein. (128 aa)
LOC105929646Uncharacterized protein. (103 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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