STRINGSTRING
LOC105929358 LOC105929358 LOC105927874 LOC105927874 LOC105917259 LOC105917259 hacd4 hacd4 LOC105918976 LOC105918976 LOC105927747 LOC105927747 depdc4 depdc4 LOC105915482 LOC105915482 elovl6 elovl6 ENSFHEP00000007506 ENSFHEP00000007506 ENSFHEP00000008321 ENSFHEP00000008321 tecr tecr LOC105926463 LOC105926463 hacd1 hacd1 ENSFHEP00000011653 ENSFHEP00000011653 acox1 acox1 LOC105915962 LOC105915962 LOC105915960 LOC105915960 LOC105932036 LOC105932036 acaa1 acaa1 LOC105925265 LOC105925265 tcp11 tcp11 znf277 znf277 abhd13 abhd13 bsn bsn ENSFHEP00000016888 ENSFHEP00000016888 abhd17b abhd17b hsd17b12 hsd17b12 LOC105927915 LOC105927915 LOC105928229 LOC105928229 LOC105934209 LOC105934209 LOC105938725 LOC105938725 HACD3 HACD3 LOC105937569 LOC105937569 LOC105927837 LOC105927837 acot7 acot7 abhd12b abhd12b acox3 acox3 tcp11l2 tcp11l2 hacd3 hacd3 hsdl2 hsdl2 acot9 acot9 LOC105939096 LOC105939096 LOC105927029 LOC105927029 ENSFHEP00000026064 ENSFHEP00000026064 LOC105937123 LOC105937123 elovl4 elovl4 LOC105919036 LOC105919036 LOC105918829 LOC105918829 LOC105915952 LOC105915952 sltm sltm hsdl1 hsdl1 hacd2 hacd2 elovl7 elovl7 hsd17b4 hsd17b4 depdc7 depdc7 ENSFHEP00000033483 ENSFHEP00000033483 LOC105936448 LOC105936448 tcp11l1 tcp11l1 pggt1b pggt1b elovl1 elovl1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC105929358Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
LOC105927874Elongation of very long chain fatty acids protein. (263 aa)
LOC105917259Fatty acid desaturase 2. (361 aa)
hacd4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (156 aa)
LOC105918976DEP domain-containing protein. (569 aa)
LOC105927747Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (347 aa)
depdc4Si:ch211-265o23.1. (543 aa)
LOC105915482Bassoon (presynaptic cytomatrix protein) b. (3393 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
ENSFHEP00000007506Elongation of very long chain fatty acids protein. (275 aa)
ENSFHEP00000008321BAAT_C domain-containing protein. (137 aa)
tecrTrans-2,3-enoyl-CoA reductase b. (308 aa)
LOC105926463Elongation of very long chain fatty acids protein. (268 aa)
hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (242 aa)
ENSFHEP00000011653Acyl-CoA_ox_N domain-containing protein. (137 aa)
acox1Acyl-CoA oxidase 1, palmitoyl. (545 aa)
LOC105915962Uncharacterized protein. (443 aa)
LOC105915960Uncharacterized protein. (420 aa)
LOC105932036Trans-2,3-enoyl-CoA reductase a. (342 aa)
acaa13-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (437 aa)
LOC105925265Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (553 aa)
tcp11Uncharacterized protein. (490 aa)
znf277Zinc finger protein 277. (426 aa)
abhd13Alpha/beta hydrolase domain-containing protein 13. (351 aa)
bsnUncharacterized protein. (3545 aa)
ENSFHEP00000016888Si:ch211-117n7.7. (347 aa)
abhd17bAlpha/beta hydrolase domain-containing protein 17B. (288 aa)
hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
LOC105927915Uncharacterized protein. (101 aa)
LOC105928229Fatty acid desaturase 1. (445 aa)
LOC105934209Alpha/beta hydrolase domain-containing protein 17A. (361 aa)
LOC105938725Stearoyl-CoA desaturase b; Belongs to the fatty acid desaturase type 1 family. (332 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (360 aa)
LOC105937569Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (312 aa)
LOC105927837Alpha/beta hydrolase domain-containing protein 17A. (321 aa)
acot7Acyl-CoA thioesterase 7. (365 aa)
abhd12bHydrolase_4 domain-containing protein. (323 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (613 aa)
tcp11l2T-complex 11, testis-specific-like 2. (535 aa)
hacd3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (357 aa)
hsdl2Hydroxysteroid dehydrogenase 2-like protein. (479 aa)
acot9Acyl-CoA thioesterase 9, tandem duplicate 2. (480 aa)
LOC105939096Uncharacterized protein. (466 aa)
LOC105927029Uncharacterized protein. (415 aa)
ENSFHEP00000026064Elongation of very long chain fatty acids protein. (222 aa)
LOC105937123Acyl-CoA thioesterase 16. (426 aa)
elovl4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (316 aa)
LOC105919036Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
LOC105918829Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (344 aa)
LOC105915952Sterol carrier protein 2b. (116 aa)
sltmSAFB-like, transcription modulator. (856 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (319 aa)
hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (244 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
hsd17b4Retinol dehydrogenase 11. (737 aa)
depdc7DEP domain containing 7, paralog a. (538 aa)
ENSFHEP00000033483Trans-2,3-enoyl-CoA reductase-like 2a. (247 aa)
LOC105936448Elongation of very long chain fatty acids protein. (265 aa)
tcp11l1T-complex 11, testis-specific-like 1. (494 aa)
pggt1bProtein geranylgeranyltransferase type I, beta subunit. (371 aa)
elovl1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (377 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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