STRINGSTRING
pold1 pold1 rfc4 rfc4 pcna pcna mlh3 mlh3 ENSFHEP00000031592 ENSFHEP00000031592 meiob meiob pold3 pold3 rfc2 rfc2 pms1 pms1 pold2 pold2 rfc1 rfc1 fbh1 fbh1 msh2 msh2 lig1 lig1 rpa1 rpa1 ssbp1 ssbp1 rexo4 rexo4 ENSFHEP00000021362 ENSFHEP00000021362 ENSFHEP00000021011 ENSFHEP00000021011 msh3 msh3 LOC105939880 LOC105939880 ppil3 ppil3 mlh1 mlh1 LOC105937671 LOC105937671 trex1 trex1 msh4 msh4 stn1 stn1 LOC105917564 LOC105917564 msh5 msh5 RPA1 RPA1 pold4 pold4 LOC105917713 LOC105917713 yju2 yju2 LOC105923252 LOC105923252 isg20l2 isg20l2 msh6 msh6 exo1 exo1 rfc5 rfc5 rfc3 rfc3 rpa3 rpa3 LOC105926267 LOC105926267 pms2 pms2 LOC105933746 LOC105933746
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pold1DNA polymerase. (1152 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
mlh3WW domain-containing protein. (374 aa)
ENSFHEP00000031592HATPase_c domain-containing protein. (112 aa)
meiobMethionine sulfoxide reductase B1b. (385 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (290 aa)
rfc2Replication factor C (activator 1) 2. (375 aa)
pms1PMS1 homolog 1, mismatch repair system component. (807 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
rfc1Replication factor C subunit 1. (1161 aa)
fbh1F-box DNA helicase 1. (1099 aa)
msh2MutS homolog 2 (E. coli). (524 aa)
lig1DNA ligase. (742 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (604 aa)
ssbp1Single-stranded DNA-binding protein, mitochondrial. (147 aa)
rexo4REX4 homolog, 3'-5' exonuclease. (400 aa)
ENSFHEP00000021362Replication protein A2. (267 aa)
ENSFHEP00000021011PRKR interacting protein 1. (135 aa)
msh3MutS homolog 3 (E. coli). (924 aa)
LOC105939880Uncharacterized protein. (168 aa)
ppil3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (715 aa)
LOC105937671RPA_C domain-containing protein. (247 aa)
trex1DNA polymerase III PolC-type. (198 aa)
msh4DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (854 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (357 aa)
LOC105917564Calcium binding protein 5a. (192 aa)
msh5MutS homolog 5. (816 aa)
RPA1Uncharacterized protein. (253 aa)
pold4Uncharacterized protein. (124 aa)
LOC105917713Src homology 2 domain containing transforming protein D, a. (416 aa)
yju2YJU2 splicing factor homolog. (348 aa)
LOC105923252ATPase family AAA domain containing 5a. (1743 aa)
isg20l2Interferon stimulated exonuclease gene 20-like 2. (333 aa)
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1301 aa)
exo1Exonuclease 1. (743 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rpa3Replication protein A3. (122 aa)
LOC105926267Interferon stimulated exonuclease gene 20 2-like protein. (332 aa)
pms2PMS1 homolog 2, mismatch repair system component. (848 aa)
LOC105933746MutS homolog 2 (E. coli). (469 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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