STRINGSTRING
bmp4 bmp4 ppp2ca ppp2ca MATN2 MATN2 LOC105920955 LOC105920955 LOC105924806 LOC105924806 rbl1 rbl1 LOC105922275 LOC105922275 LOC105929125 LOC105929125 tgfb3 tgfb3 SMURF2 SMURF2 LOC105930854 LOC105930854 INHBC INHBC LOC105918135 LOC105918135 usf2 usf2 bmpr1b bmpr1b LOC105922368 LOC105922368 ENSFHEP00000013800 ENSFHEP00000013800 LOC105920438 LOC105920438 LOC105922440 LOC105922440 tfdp1 tfdp1 ifng1 ifng1 mapk1 mapk1 LOC105920529 LOC105920529 LOC105938966 LOC105938966 ltbp4 ltbp4 nodal nodal crebbp crebbp dcc dcc ENSFHEP00000010436 ENSFHEP00000010436 ENSFHEP00000010429 ENSFHEP00000010429 LOC105924936 LOC105924936 LOC105929913 LOC105929913 rgmb rgmb smurf1 smurf1 pknox1 pknox1 THSD4 THSD4 LOC105931003 LOC105931003 LOC105921936 LOC105921936 TGFBR2 TGFBR2 e2f4 e2f4 ENSFHEP00000007984 ENSFHEP00000007984 LOC105933441 LOC105933441 smad1 smad1 LOC105931695 LOC105931695 ENSFHEP00000006134 ENSFHEP00000006134 ENSFHEP00000006124 ENSFHEP00000006124 LOC105927694 LOC105927694 LOC105939150 LOC105939150 LOC105930061 LOC105930061 LOC105936869 LOC105936869 LOC105925994 LOC105925994 LOC105938719 LOC105938719 fst fst LOC105938065 LOC105938065 LOC105919548 LOC105919548 smad2 smad2 LOC105920199 LOC105920199 LOC105920975 LOC105920975 ENSFHEP00000004435 ENSFHEP00000004435 LOC105917236 LOC105917236 NBL1 NBL1 LTBP3 LTBP3 LOC105927124 LOC105927124 pknox2 pknox2 LOC105918977 LOC105918977 LOC105915540 LOC105915540 LOC105932304 LOC105932304 LOC105936361 LOC105936361 LOC105915546 LOC105915546 LOC105918990 LOC105918990 LOC105918991 LOC105918991 LOC105915606 LOC105915606 LOC105926602 LOC105926602 rgma rgma LOC105940274 LOC105940274 smad9 smad9 TGFB3 TGFB3 ENSFHEP00000000227 ENSFHEP00000000227 LOC105927895 LOC105927895 LOC105921341 LOC105921341 ENSFHEP00000034755 ENSFHEP00000034755 grem2 grem2 LOC105916769 LOC105916769 ACVR1 ACVR1 ACVR1C ACVR1C LOC105928476 LOC105928476 bmp5 bmp5 LOC105927928 LOC105927928 LOC105934750 LOC105934750 ENSFHEP00000033938 ENSFHEP00000033938 LOC105935878 LOC105935878 LOC105917364 LOC105917364 ENSFHEP00000033534 ENSFHEP00000033534 LOC105916804 LOC105916804 rbx1 rbx1 ENSFHEP00000033245 ENSFHEP00000033245 ANKFN1 ANKFN1 ENSFHEP00000033086 ENSFHEP00000033086 ENSFHEP00000033073 ENSFHEP00000033073 skp1 skp1 LOC105930774 LOC105930774 LOC105923581 LOC105923581 LOC105922446 LOC105922446 id4 id4 LOC105935861 LOC105935861 ENSFHEP00000032303 ENSFHEP00000032303 ENSFHEP00000031911 ENSFHEP00000031911 LOC105930844 LOC105930844 bmpr1a bmpr1a LOC105926907 LOC105926907 RPS6KB2 RPS6KB2 rps6kb1 rps6kb1 neo1 neo1 GREM1 GREM1 LOC105938393 LOC105938393 id2 id2 myc myc LOC105921852 LOC105921852 LOC105936335 LOC105936335 gdf6 gdf6 ENSFHEP00000026167 ENSFHEP00000026167 LOC105939051 LOC105939051 ENSFHEP00000026069 ENSFHEP00000026069 nog nog LOC105919484 LOC105919484 pitx2 pitx2 bmp8a bmp8a bmpr2 bmpr2 matn1 matn1 LOC105920743 LOC105920743 ENSFHEP00000024203 ENSFHEP00000024203 zfyve9 zfyve9 acvr2a acvr2a dcn dcn smad7 smad7 acvr2b acvr2b LOC105927061 LOC105927061 ROCK1 ROCK1 gdf5 gdf5 LOC105936367 LOC105936367 LOC105921446 LOC105921446 FBN1 FBN1 ENSFHEP00000022032 ENSFHEP00000022032 amh amh ACVR1B ACVR1B LOC105934698 LOC105934698 ENSFHEP00000020850 ENSFHEP00000020850 LOC105936994 LOC105936994 LOC105922834 LOC105922834 LOC105919134 LOC105919134 LOC105939869 LOC105939869 smad6 smad6 LOC105934781 LOC105934781 chrd chrd LOC105930725 LOC105930725 fstl3 fstl3 LOC105933078 LOC105933078 ENSFHEP00000019207 ENSFHEP00000019207 ep300 ep300 ldah ldah hamp hamp LOC105930802 LOC105930802 pitx1 pitx1 bmp2 bmp2 LOC105939894 LOC105939894
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bmp4Bone morphogenetic protein 4. (399 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
MATN2Matrilin 2. (794 aa)
LOC105920955Serine/threonine-protein phosphatase. (309 aa)
LOC105924806Homeobox protein. (294 aa)
rbl1Retinoblastoma-like 1 (p107). (1058 aa)
LOC105922275Inhibin subunit beta B. (394 aa)
LOC105929125Transforming protein RhoA. (193 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
SMURF2E3 ubiquitin-protein ligase. (785 aa)
LOC105930854E1A binding protein p300 a. (2838 aa)
INHBCInhibin subunit beta C. (383 aa)
LOC105918135TGFB-induced factor homeobox 1. (303 aa)
usf2Upstream transcription factor 2, c-fos interacting. (309 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
LOC105922368Inhibin subunit beta Ab. (396 aa)
ENSFHEP00000013800Gremlin 1a, DAN family BMP antagonist. (181 aa)
LOC105920438Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
LOC105922440Uncharacterized protein. (470 aa)
tfdp1Transcription factor. (425 aa)
ifng1Uncharacterized protein. (204 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC105920529Mothers against decapentaplegic homolog. (520 aa)
LOC105938966RGM domain family, member D. (458 aa)
ltbp4Uncharacterized protein. (1644 aa)
nodalNodal-related 2. (379 aa)
crebbpCREB binding protein a. (2270 aa)
dccDCC netrin 1 receptor. (1413 aa)
ENSFHEP00000010436TGF_BETA_2 domain-containing protein. (114 aa)
ENSFHEP00000010429Meis_PKNOX_N domain-containing protein. (160 aa)
LOC105924936CREB binding protein b. (2424 aa)
LOC105929913E3 ubiquitin-protein ligase. (770 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (472 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
pknox1Pbx/knotted 1 homeobox 1.1. (313 aa)
THSD4Thrombospondin type 1 domain containing 4. (963 aa)
LOC105931003Anti-dorsalizing morphogenic protein. (380 aa)
LOC105921936Serine/threonine-protein phosphatase. (309 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
e2f4E2F transcription factor 4. (381 aa)
ENSFHEP00000007984Matrilin 3b. (407 aa)
LOC105933441Uncharacterized protein. (82 aa)
smad1Mothers against decapentaplegic homolog. (488 aa)
LOC105931695Homeobox domain-containing protein. (545 aa)
ENSFHEP00000006134Uncharacterized protein. (205 aa)
ENSFHEP00000006124Uncharacterized protein. (355 aa)
LOC105927694Inhibitor of DNA binding 3. (116 aa)
LOC105939150Bone morphogenetic protein 16. (476 aa)
LOC105930061Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC105936869Fibrillin 2b. (2703 aa)
LOC105925994Bone morphogenetic protein 7a. (393 aa)
LOC105938719Mothers against decapentaplegic homolog. (467 aa)
fstFollistatin a. (349 aa)
LOC105938065Fibronectin type-III domain-containing protein. (1067 aa)
LOC105919548Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
smad2Mothers against decapentaplegic homolog. (358 aa)
LOC105920199TGF_BETA_2 domain-containing protein. (446 aa)
LOC105920975Uncharacterized protein. (200 aa)
ENSFHEP00000004435E2F_TDP domain-containing protein. (162 aa)
LOC105917236Latent transforming growth factor beta binding protein 1. (1107 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (196 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1239 aa)
LOC105927124Uncharacterized protein. (193 aa)
pknox2Pbx/knotted 1 homeobox 2. (485 aa)
LOC105918977Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
LOC105915540Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (732 aa)
LOC105932304Bone morphogenetic protein 7b. (427 aa)
LOC105936361Mothers against decapentaplegic homolog. (427 aa)
LOC105915546Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
LOC105918990BMP and activin membrane-bound inhibitor homolog. (256 aa)
LOC105918991BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC105915606Zinc finger, FYVE domain containing 16. (1413 aa)
LOC105926602Uncharacterized protein. (1259 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (445 aa)
LOC105940274Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (673 aa)
smad9Mothers against decapentaplegic homolog. (467 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
ENSFHEP00000000227Cullin 1b; Belongs to the cullin family. (471 aa)
LOC105927895Si:dkey-235d18.5. (816 aa)
LOC105921341MH2 domain-containing protein. (222 aa)
ENSFHEP00000034755MH1 domain-containing protein. (154 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
LOC105916769MYCL proto-oncogene, bHLH transcription factor b. (464 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (487 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
LOC105928476PLAC domain-containing protein. (1180 aa)
bmp5Bone morphogenetic protein 5. (465 aa)
LOC105927928Mothers against decapentaplegic homolog. (425 aa)
LOC105934750Zgc:113307. (366 aa)
ENSFHEP00000033938TB domain-containing protein. (111 aa)
LOC105935878Uncharacterized protein. (202 aa)
LOC105917364AMOP domain-containing protein. (445 aa)
ENSFHEP00000033534Uncharacterized protein. (79 aa)
LOC105916804BHLH domain-containing protein. (318 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
ENSFHEP00000033245Activin_recp domain-containing protein. (189 aa)
ANKFN1Ankyrin repeat and fibronectin type III domain containing 1. (423 aa)
ENSFHEP00000033086Uncharacterized protein. (361 aa)
ENSFHEP00000033073Noggin; Belongs to the noggin family. (216 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC105930774Mothers against decapentaplegic homolog. (393 aa)
LOC105923581Uncharacterized protein. (89 aa)
LOC105922446Inhibitor of DNA binding 1, HLH protein. (127 aa)
id4Inhibitor of DNA binding 4. (216 aa)
LOC105935861Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (498 aa)
ENSFHEP00000032303IF rod domain-containing protein; Belongs to the intermediate filament family. (248 aa)
ENSFHEP00000031911Uncharacterized protein. (1534 aa)
LOC105930844TGF_BETA_2 domain-containing protein. (390 aa)
bmpr1aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
LOC105926907Southpaw. (409 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (471 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
neo1Neogenin 1b. (1446 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (153 aa)
LOC105938393Thrombospondin 1a. (1171 aa)
id2Inhibitor of DNA binding 2a. (132 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (432 aa)
LOC105921852TGFb_propeptide domain-containing protein. (373 aa)
LOC105936335Thrombospondin 1b. (1169 aa)
gdf6Growth differentiation factor 6a. (414 aa)
ENSFHEP00000026167Uncharacterized protein. (77 aa)
LOC105939051Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
ENSFHEP00000026069Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. (419 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
LOC105919484Mothers against decapentaplegic homolog. (412 aa)
pitx2Homeobox protein. (312 aa)
bmp8aBone morphogenetic protein 8a. (435 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1050 aa)
matn1Matrilin 1. (483 aa)
LOC105920743Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (317 aa)
ENSFHEP00000024203MH1 domain-containing protein. (95 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1175 aa)
acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
dcnDecorin; May affect the rate of fibrils formation. (362 aa)
smad7Mothers against decapentaplegic homolog. (378 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
LOC105927061Fibromodulin b. (346 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1. (521 aa)
gdf5Growth differentiation factor 5. (487 aa)
LOC105936367Mothers against decapentaplegic homolog. (503 aa)
LOC105921446E2F transcription factor 5. (362 aa)
FBN1Fibrillin 1. (2760 aa)
ENSFHEP00000022032Noggin; Belongs to the noggin family. (210 aa)
amhAnti-Mullerian hormone. (492 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
LOC105934698Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (532 aa)
ENSFHEP00000020850Matrilin 4. (468 aa)
LOC105936994Left-right determination factor. (358 aa)
LOC105922834BHLH domain-containing protein. (346 aa)
LOC105919134Hemojuvelin BMP co-receptor. (401 aa)
LOC105939869Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
smad6Mothers against decapentaplegic homolog. (492 aa)
LOC105934781Fibromodulin a. (349 aa)
chrdChordin; Belongs to the chordin family. (1031 aa)
LOC105930725Matrilin 3a. (339 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (150 aa)
LOC105933078Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
ENSFHEP00000019207Uncharacterized protein. (118 aa)
ep300E1A binding protein p300 b. (2738 aa)
ldahLipid droplet associated hydrolase. (387 aa)
hampUncharacterized protein. (89 aa)
LOC105930802Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
pitx1Homeobox protein. (312 aa)
bmp2Bone morphogenetic protein 2b. (419 aa)
LOC105939894Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (479 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.