STRINGSTRING
cacna1s cacna1s LOC105928914 LOC105928914 LOC105929512 LOC105929512 LOC105934126 LOC105934126 LOC105934100 LOC105934100 ENSFHEP00000001379 ENSFHEP00000001379 ENSFHEP00000001390 ENSFHEP00000001390 LOC105934050 LOC105934050 map2k7 map2k7 REM1 REM1 ENSFHEP00000002487 ENSFHEP00000002487 ENSFHEP00000002496 ENSFHEP00000002496 sos2 sos2 LOC105936828 LOC105936828 prkacb prkacb mapk10 mapk10 PRKCB PRKCB LOC105919586 LOC105919586 LOC105938700 LOC105938700 LOC105928568 LOC105928568 LOC105931778 LOC105931778 LOC105930621 LOC105930621 LOC105926211 LOC105926211 jmjd7 jmjd7 LOC105925532 LOC105925532 LOC105915485 LOC105915485 LOC105927744 LOC105927744 LOC105937195 LOC105937195 ENSFHEP00000005790 ENSFHEP00000005790 map3k4 map3k4 ELK3 ELK3 ENSFHEP00000007104 ENSFHEP00000007104 LOC105928246 LOC105928246 itpr2 itpr2 adcy3 adcy3 kras kras ENSFHEP00000008641 ENSFHEP00000008641 LOC105917709 LOC105917709 LOC105928222 LOC105928222 ENSFHEP00000009233 ENSFHEP00000009233 LOC105929235 LOC105929235 LOC105926483 LOC105926483 ADCY9 ADCY9 gnrh1 gnrh1 LOC105933358 LOC105933358 LOC105929249 LOC105929249 adcy8 adcy8 LOC105925855 LOC105925855 LOC105924471 LOC105924471 map2k2 map2k2 LOC105931543 LOC105931543 LOC105931589 LOC105931589 adcy7 adcy7 ENSFHEP00000011198 ENSFHEP00000011198 SRC SRC cga cga ENSFHEP00000011635 ENSFHEP00000011635 LOC105920517 LOC105920517 mapk1 mapk1 LOC105938409 LOC105938409 LOC105921780 LOC105921780 LOC105918234 LOC105918234 LOC105916404 LOC105916404 gem gem ENSFHEP00000013026 ENSFHEP00000013026 ENSFHEP00000013297 ENSFHEP00000013297 grap2 grap2 LOC105935238 LOC105935238 adcy6 adcy6 map2k4 map2k4 LOC105929835 LOC105929835 LOC105935986 LOC105935986 LOC105921046 LOC105921046 LOC105930852 LOC105930852 ENSFHEP00000015797 ENSFHEP00000015797 ENSFHEP00000015836 ENSFHEP00000015836 LOC105930289 LOC105930289 LOC105931976 LOC105931976 LOC105935366 LOC105935366 LOC105916870 LOC105916870 LOC105934248 LOC105934248 LOC105927386 LOC105927386 mmp14 mmp14 PLCB4 PLCB4 LOC105939894 LOC105939894 LOC105920313 LOC105920313 LOC105927291 LOC105927291 LOC105919179 LOC105919179 calm2 calm2 LOC105939921 LOC105939921 cacna1f cacna1f LOC105938139 LOC105938139 CACNA1D CACNA1D LOC105928969 LOC105928969 map3k3 map3k3 PTX3 PTX3 gnas gnas LOC105929401 LOC105929401 mapk7 mapk7 raf1 raf1 mmp2 mmp2 LOC105926005 LOC105926005 map2k1 map2k1 atf4 atf4 LOC105931725 LOC105931725 LOC105932885 LOC105932885 PLD1 PLD1 prkcd prkcd pla2g4c pla2g4c hras hras LOC105915402 LOC105915402 CSDE1 CSDE1 grb2 grb2 LOC105920547 LOC105920547 LOC105919044 LOC105919044 LOC105917085 LOC105917085 LOC105935432 LOC105935432 pla2g4a pla2g4a LOC105929932 LOC105929932 LOC105932051 LOC105932051 calml4 calml4 adcy5 adcy5 LOC105922347 LOC105922347 LOC105929802 LOC105929802 LOC105936550 LOC105936550 PRKCA PRKCA ENSFHEP00000031565 ENSFHEP00000031565 LOC105934240 LOC105934240 rrad rrad CDC42 CDC42 PLCB1 PLCB1 LOC105916319 LOC105916319 LOC105925607 LOC105925607 LOC105937030 LOC105937030 LOC105919697 LOC105919697 fshb fshb LOC105921477 LOC105921477 gnrh2 gnrh2 ENSFHEP00000035146 ENSFHEP00000035146 ENSFHEP00000035197 ENSFHEP00000035197
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1714 aa)
LOC105928914Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (324 aa)
LOC105929512Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1189 aa)
LOC105934126G_PROTEIN_RECEP_F1_2 domain-containing protein. (415 aa)
LOC105934100Cell division control protein 42. (191 aa)
ENSFHEP00000001379Ion_trans domain-containing protein. (490 aa)
ENSFHEP00000001390MIR domain-containing protein. (200 aa)
LOC105934050Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (664 aa)
map2k7Mitogen-activated protein kinase kinase 7. (423 aa)
REM1RRAD and GEM like GTPase 1. (307 aa)
ENSFHEP00000002487Protein kinase domain-containing protein. (104 aa)
ENSFHEP00000002496CaMKII_AD domain-containing protein. (192 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1323 aa)
LOC105936828Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
mapk10Mitogen-activated protein kinase 10. (411 aa)
PRKCBProtein kinase C. (647 aa)
LOC105919586Receptor protein-tyrosine kinase. (1102 aa)
LOC105938700Mitogen-activated protein kinase. (460 aa)
LOC105928568Cell division control protein 42. (191 aa)
LOC105931778Mitogen-activated protein kinase. (357 aa)
LOC105930621Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC105926211Phosphoinositide phospholipase C. (1039 aa)
jmjd7Jumonji domain containing 7. (368 aa)
LOC105925532Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily. (487 aa)
LOC105915485Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1961 aa)
LOC105927744Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC105937195Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (544 aa)
ENSFHEP00000005790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (370 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1576 aa)
ELK3ETS transcription factor ELK3. (391 aa)
ENSFHEP00000007104Uncharacterized protein. (603 aa)
LOC105928246Heparin-binding EGF-like growth factor a. (222 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2636 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
ENSFHEP00000008641Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (448 aa)
LOC105917709Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (402 aa)
LOC105928222Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
ENSFHEP00000009233PH_14 domain-containing protein. (93 aa)
LOC105929235Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (334 aa)
LOC105926483Dual specificity mitogen-activated protein kinase kinase 3. (358 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1434 aa)
gnrh1Gonadotropin releasing hormone type 1. (96 aa)
LOC105933358Gonadotropin subunit beta-2; Involved in gametogenesis and steroidogenesis. (147 aa)
LOC105929249Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1446 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
LOC105925855Mitogen-activated protein kinase. (363 aa)
LOC105924471Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC105931543Uncharacterized protein. (191 aa)
LOC105931589Uncharacterized protein. (191 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
ENSFHEP00000011198Protein kinase domain-containing protein. (225 aa)
SRCTyrosine-protein kinase. (548 aa)
cgaGlycoprotein hormones alpha chain; Shared alpha chain of heterodimeric glycoprotein hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. Involved in gametogenesis and steroidogenesis. (125 aa)
ENSFHEP00000011635Uncharacterized protein. (158 aa)
LOC105920517Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC105938409Mitogen-activated protein kinase kinase kinase 22. (582 aa)
LOC105921780G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa)
LOC105918234Tyrosine-protein kinase. (550 aa)
LOC105916404Gonadotropin releasing hormone receptor type A. (415 aa)
gemGTP binding protein overexpressed in skeletal muscle. (306 aa)
ENSFHEP00000013026JunE proto-oncogene, AP-1 transcription factor subunit. (334 aa)
ENSFHEP00000013297BZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
grap2GRB2 related adaptor protein 2a. (257 aa)
LOC105935238Adenylate cyclase 1b. (941 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1207 aa)
map2k4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (433 aa)
LOC105929835Mitogen-activated protein kinase. (361 aa)
LOC105935986GNAS complex locus. (379 aa)
LOC105921046Early growth response protein 1. (435 aa)
LOC105930852Mitogen-activated protein kinase. (408 aa)
ENSFHEP00000015797Ion_trans domain-containing protein. (140 aa)
ENSFHEP00000015836Ca_chan_IQ domain-containing protein. (513 aa)
LOC105930289Matrix metallopeptidase 14b (membrane-inserted). (679 aa)
LOC105931976Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
LOC105935366Phospholipase. (1054 aa)
LOC105916870ETS domain-containing protein. (337 aa)
LOC105934248Inositol 1,4,5-trisphosphate receptor, type 1b. (2688 aa)
LOC105927386Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (420 aa)
mmp14Matrix metallopeptidase 14a (membrane-inserted). (557 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1238 aa)
LOC105939894Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (479 aa)
LOC105920313Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa)
LOC105927291Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (91 aa)
LOC105919179Adenylate cyclase type 4. (1297 aa)
calm2Calmodulin 2. (149 aa)
LOC105939921Zgc:55558. (187 aa)
cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1614 aa)
LOC105938139Guanine nucleotide-binding protein subunit alpha-11. (357 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2076 aa)
LOC105928969Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1178 aa)
map3k3Mitogen-activated protein kinase kinase kinase 3. (617 aa)
PTX3Pentraxin 3, long a. (455 aa)
gnasUncharacterized protein. (379 aa)
LOC105929401Phospholipase. (969 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1079 aa)
raf1RAF proto-oncogene serine/threonine-protein kinase. (671 aa)
mmp2Matrix metallopeptidase 2. (540 aa)
LOC105926005Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
atf4Activating transcription factor 4b. (447 aa)
LOC105931725Mitogen-activated protein kinase. (360 aa)
LOC105932885Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
PLD1Phospholipase. (1039 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
pla2g4cPLA2c domain-containing protein. (608 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC105915402Activating transcription factor 4a. (442 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (870 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC105920547ETS transcription factor ELK1. (544 aa)
LOC105919044Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
LOC105917085Mitogen-activated protein kinase. (420 aa)
LOC105935432Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
pla2g4aPhospholipase A2. (749 aa)
LOC105929932Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
LOC105932051Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
calml4Calmodulin-like 4a. (153 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
LOC105922347Son of sevenless homolog 1 (Drosophila). (1175 aa)
LOC105929802Mitogen-activated protein kinase. (362 aa)
LOC105936550Uncharacterized protein; Belongs to the calmodulin family. (207 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ENSFHEP00000031565Protein kinase domain-containing protein. (105 aa)
LOC105934240Mitogen-activated protein kinase. (364 aa)
rradRas-related associated with diabetes. (309 aa)
CDC42Cell division control protein 42. (191 aa)
PLCB1Phosphoinositide phospholipase C. (1062 aa)
LOC105916319Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1987 aa)
LOC105925607Calmodulin. (149 aa)
LOC105937030Inositol 1,4,5-trisphosphate receptor, type 1a. (2659 aa)
LOC105919697Gonadotropin releasing hormone receptor 4. (416 aa)
fshbGonadotropin subunit beta-1; Involved in gametogenesis and steroidogenesis. (114 aa)
LOC105921477Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (948 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (83 aa)
ENSFHEP00000035146Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (163 aa)
ENSFHEP00000035197Protein kinase domain-containing protein. (160 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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