(11 nodes) Chagas disease network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000014695	Ig_4 domain-containing protein. (185 aa)
	ENSFHEP00000014608	Uncharacterized protein. (183 aa)
	ENSFHEP00000032737	Angiotensin-converting enzyme. (703 aa)
	ENSFHEP00000003057	DDE_Tnp_1_7 domain-containing protein. (523 aa)
	LOC105925442	PiggyBac transposable element-derived protein 4. (681 aa)
	LOC105923514	Uncharacterized protein. (213 aa)
	C1QA	Complement C1q A chain. (257 aa)
	LOC105935626	Angiotensin-converting enzyme. (1291 aa)
	LOC105924062	DDE_Tnp_1_7 domain-containing protein. (524 aa)
	LOC105938255	Complement C1q C chain. (240 aa)
	LOC105933189	Uncharacterized protein. (169 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QA	LOC105938255	ENSFHEP00000032687	ENSFHEP00000017577	Complement C1q A chain.	Complement C1q C chain.	0.987
ENSFHEP00000003057	ENSFHEP00000014608	ENSFHEP00000003057	ENSFHEP00000014608	DDE_Tnp_1_7 domain-containing protein.	Uncharacterized protein.	0.957
ENSFHEP00000003057	ENSFHEP00000014695	ENSFHEP00000003057	ENSFHEP00000014695	DDE_Tnp_1_7 domain-containing protein.	Ig_4 domain-containing protein.	0.957
ENSFHEP00000003057	LOC105923514	ENSFHEP00000003057	ENSFHEP00000033593	DDE_Tnp_1_7 domain-containing protein.	Uncharacterized protein.	0.950
ENSFHEP00000014608	ENSFHEP00000003057	ENSFHEP00000014608	ENSFHEP00000003057	Uncharacterized protein.	DDE_Tnp_1_7 domain-containing protein.	0.957
ENSFHEP00000014608	LOC105923514	ENSFHEP00000014608	ENSFHEP00000033593	Uncharacterized protein.	Uncharacterized protein.	0.995
ENSFHEP00000014608	LOC105924062	ENSFHEP00000014608	ENSFHEP00000023790	Uncharacterized protein.	DDE_Tnp_1_7 domain-containing protein.	0.957
ENSFHEP00000014608	LOC105925442	ENSFHEP00000014608	ENSFHEP00000006144	Uncharacterized protein.	PiggyBac transposable element-derived protein 4.	0.988
ENSFHEP00000014608	LOC105933189	ENSFHEP00000014608	ENSFHEP00000014704	Uncharacterized protein.	Uncharacterized protein.	0.997
ENSFHEP00000014695	ENSFHEP00000003057	ENSFHEP00000014695	ENSFHEP00000003057	Ig_4 domain-containing protein.	DDE_Tnp_1_7 domain-containing protein.	0.957
ENSFHEP00000014695	LOC105923514	ENSFHEP00000014695	ENSFHEP00000033593	Ig_4 domain-containing protein.	Uncharacterized protein.	0.995
ENSFHEP00000014695	LOC105924062	ENSFHEP00000014695	ENSFHEP00000023790	Ig_4 domain-containing protein.	DDE_Tnp_1_7 domain-containing protein.	0.957
ENSFHEP00000014695	LOC105925442	ENSFHEP00000014695	ENSFHEP00000006144	Ig_4 domain-containing protein.	PiggyBac transposable element-derived protein 4.	0.988
ENSFHEP00000014695	LOC105933189	ENSFHEP00000014695	ENSFHEP00000014704	Ig_4 domain-containing protein.	Uncharacterized protein.	0.997
LOC105923514	ENSFHEP00000003057	ENSFHEP00000033593	ENSFHEP00000003057	Uncharacterized protein.	DDE_Tnp_1_7 domain-containing protein.	0.950
LOC105923514	ENSFHEP00000014608	ENSFHEP00000033593	ENSFHEP00000014608	Uncharacterized protein.	Uncharacterized protein.	0.995
LOC105923514	ENSFHEP00000014695	ENSFHEP00000033593	ENSFHEP00000014695	Uncharacterized protein.	Ig_4 domain-containing protein.	0.995
LOC105923514	LOC105924062	ENSFHEP00000033593	ENSFHEP00000023790	Uncharacterized protein.	DDE_Tnp_1_7 domain-containing protein.	0.950
LOC105923514	LOC105925442	ENSFHEP00000033593	ENSFHEP00000006144	Uncharacterized protein.	PiggyBac transposable element-derived protein 4.	0.993
LOC105923514	LOC105933189	ENSFHEP00000033593	ENSFHEP00000014704	Uncharacterized protein.	Uncharacterized protein.	0.998