45 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	taf5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (745 aa)
	ENSPREP00000001027	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)
	tbpl2	Uncharacterized protein. (307 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
	LOC103459886	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (253 aa)
	taf13	TATA-box binding protein associated factor 13. (188 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	Taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (159 aa)
	taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (196 aa)
	gtf2b	General transcription factor IIB. (318 aa)
	ENSPREP00000011339	TAF4 domain-containing protein. (249 aa)
	TAF4	TATA-box binding protein associated factor 4. (878 aa)
	taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (896 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1180 aa)
	gtf2a2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	fbxw12	Si:ch73-142c19.1. (474 aa)
	tbp	TATA box binding protein. (301 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	taf2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1119 aa)
	tbpl1	TBP-like 1. (187 aa)
	taf7l	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (383 aa)
	cdk20	Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (371 aa)
	LOC103470674	General transcription factor IIH subunit. (420 aa)
	Clg8h11orf88	Uncharacterized protein. (152 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	ENSPREP00000019960	WD_REPEATS_REGION domain-containing protein. (326 aa)
	LOC103461004	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (462 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	LOC103465090	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (852 aa)
	Ctdp1	FCP1 homology domain-containing protein. (271 aa)
	LOC103466384	TAFH domain-containing protein. (863 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
	gtf2a1	General transcription factor IIA, 1. (393 aa)
	ercc2	Excision repair cross-complementation group 2. (655 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (277 aa)
	taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (243 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (599 aa)
	LOC103475759	Transcription initiation factor TFIID subunit. (1985 aa)
	taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (637 aa)
	ENSPREP00000034063	General transcription factor IIA, 1-like. (327 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Clg8h11orf88	ENSPREP00000001027	ENSPREP00000019816	ENSPREP00000001027	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.887
Clg8h11orf88	ENSPREP00000011339	ENSPREP00000019816	ENSPREP00000011339	Uncharacterized protein.	TAF4 domain-containing protein.	0.729
Clg8h11orf88	ENSPREP00000019960	ENSPREP00000019816	ENSPREP00000019960	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.767
Clg8h11orf88	ENSPREP00000034063	ENSPREP00000019816	ENSPREP00000034063	Uncharacterized protein.	General transcription factor IIA, 1-like.	0.805
Clg8h11orf88	LOC103459886	ENSPREP00000019816	ENSPREP00000004559	Uncharacterized protein.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.911
Clg8h11orf88	LOC103461004	ENSPREP00000019816	ENSPREP00000020577	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.805
Clg8h11orf88	LOC103465090	ENSPREP00000019816	ENSPREP00000024331	Uncharacterized protein.	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.729
Clg8h11orf88	LOC103466384	ENSPREP00000019816	ENSPREP00000024912	Uncharacterized protein.	TAFH domain-containing protein.	0.729
Clg8h11orf88	LOC103470674	ENSPREP00000019816	ENSPREP00000017962	Uncharacterized protein.	General transcription factor IIH subunit.	0.812
Clg8h11orf88	LOC103475759	ENSPREP00000019816	ENSPREP00000032525	Uncharacterized protein.	Transcription initiation factor TFIID subunit.	0.912
Clg8h11orf88	TAF4	ENSPREP00000019816	ENSPREP00000011437	Uncharacterized protein.	TATA-box binding protein associated factor 4.	0.729
Clg8h11orf88	Taf12	ENSPREP00000019816	ENSPREP00000007202	Uncharacterized protein.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.912
Clg8h11orf88	ccnh	ENSPREP00000019816	ENSPREP00000006353	Uncharacterized protein.	Cyclin H; Belongs to the cyclin family.	0.770
Clg8h11orf88	cdk20	ENSPREP00000019816	ENSPREP00000017826	Uncharacterized protein.	Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily.	0.627
Clg8h11orf88	cdk7	ENSPREP00000019816	ENSPREP00000003727	Uncharacterized protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.627
Clg8h11orf88	ercc2	ENSPREP00000019816	ENSPREP00000028527	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.829
Clg8h11orf88	ercc3	ENSPREP00000019816	ENSPREP00000030919	Uncharacterized protein.	Excision repair cross-complementation group 3.	0.864
Clg8h11orf88	fbxw12	ENSPREP00000019816	ENSPREP00000014002	Uncharacterized protein.	Si:ch73-142c19.1.	0.627
Clg8h11orf88	gtf2a1	ENSPREP00000019816	ENSPREP00000027319	Uncharacterized protein.	General transcription factor IIA, 1.	0.805
Clg8h11orf88	gtf2a2	ENSPREP00000019816	ENSPREP00000013132	Uncharacterized protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.904