(32 nodes) mRNA cleavage factor complex, and Protein suppressor of sable-like network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	LOC103462989	Uncharacterized protein. (1611 aa)
	LOC103462989-2	DWNN domain-containing protein. (130 aa)
	WDR33	WD repeat domain 33. (893 aa)
	nudt21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (229 aa)
	Pcf11	CID domain-containing protein. (87 aa)
	LOC103463473	Uncharacterized protein. (810 aa)
	cpsf6	Cleavage and polyadenylation specific factor 6. (586 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (653 aa)
	ENSPREP00000007025	Uncharacterized protein. (263 aa)
	ssu72	SSU72 homolog, RNA polymerase II CTD phosphatase. (194 aa)
	wdr82	WD repeat domain 82. (302 aa)
	sympk	Symplekin. (1220 aa)
	zc3h3	Zinc finger CCCH-type containing 3. (890 aa)
	cpsf2	Cleavage and polyadenylation specificity factor subunit 2. (787 aa)
	tmem240	Transmembrane protein 240a. (175 aa)
	papolg	Poly(A) polymerase gamma. (847 aa)
	cstf2	Cleavage stimulation factor, 3' pre-RNA, subunit 2. (556 aa)
	YTHDC2	YTH domain containing 2. (1418 aa)
	ENSPREP00000018529	FIP1 like 1b (S. cerevisiae). (435 aa)
	cstf3	Cleavage stimulation factor, 3' pre-RNA, subunit 3. (716 aa)
	LOC103457156	Cleavage and polyadenylation specific factor 3. (627 aa)
	cpsf1	Cleavage and polyadenylation specific factor 1. (1471 aa)
	ythdc1	YTH domain containing 1. (602 aa)
	tia1	TIA1 cytotoxic granule-associated RNA binding protein. (419 aa)
	clp1	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (441 aa)
	cpsf4	Cleavage and polyadenylation specific factor 4. (262 aa)
	Rbbp6	Uncharacterized protein. (212 aa)
	zc3h4	Zinc finger CCCH-type containing 4. (1049 aa)
	cstf1	Cleavage stimulation factor, 3' pre-RNA, subunit 1. (431 aa)
	kiaa0232	Zgc:158564. (1341 aa)
	CPSF7	Cleavage and polyadenylation specific factor 7. (451 aa)
	zc3h6	Zinc finger CCCH-type containing 6. (1018 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPSF3	CPSF7	ENSPREP00000006485	ENSPREP00000033868	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 7.	0.666
CPSF3	ENSPREP00000007025	ENSPREP00000006485	ENSPREP00000007025	Cleavage and polyadenylation specific factor 3.	Uncharacterized protein.	0.850
CPSF3	ENSPREP00000018529	ENSPREP00000006485	ENSPREP00000018529	Cleavage and polyadenylation specific factor 3.	FIP1 like 1b (S. cerevisiae).	0.976
CPSF3	LOC103462989	ENSPREP00000006485	ENSPREP00000000508	Cleavage and polyadenylation specific factor 3.	Uncharacterized protein.	0.709
CPSF3	LOC103462989-2	ENSPREP00000006485	ENSPREP00000000509	Cleavage and polyadenylation specific factor 3.	DWNN domain-containing protein.	0.709
CPSF3	LOC103463473	ENSPREP00000006485	ENSPREP00000004761	Cleavage and polyadenylation specific factor 3.	Uncharacterized protein.	0.795
CPSF3	Pcf11	ENSPREP00000006485	ENSPREP00000002252	Cleavage and polyadenylation specific factor 3.	CID domain-containing protein.	0.974
CPSF3	Rbbp6	ENSPREP00000006485	ENSPREP00000028627	Cleavage and polyadenylation specific factor 3.	Uncharacterized protein.	0.709
CPSF3	WDR33	ENSPREP00000006485	ENSPREP00000001646	Cleavage and polyadenylation specific factor 3.	WD repeat domain 33.	0.990
CPSF3	YTHDC2	ENSPREP00000006485	ENSPREP00000017945	Cleavage and polyadenylation specific factor 3.	YTH domain containing 2.	0.456
CPSF3	clp1	ENSPREP00000006485	ENSPREP00000026331	Cleavage and polyadenylation specific factor 3.	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	0.861
CPSF3	cpsf1	ENSPREP00000006485	ENSPREP00000024232	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 1.	0.994
CPSF3	cpsf2	ENSPREP00000006485	ENSPREP00000013231	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specificity factor subunit 2.	0.992
CPSF3	cpsf4	ENSPREP00000006485	ENSPREP00000026877	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 4.	0.990
CPSF3	cpsf6	ENSPREP00000006485	ENSPREP00000006376	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 6.	0.666
CPSF3	cstf1	ENSPREP00000006485	ENSPREP00000030683	Cleavage and polyadenylation specific factor 3.	Cleavage stimulation factor, 3' pre-RNA, subunit 1.	0.903
CPSF3	cstf2	ENSPREP00000006485	ENSPREP00000016984	Cleavage and polyadenylation specific factor 3.	Cleavage stimulation factor, 3' pre-RNA, subunit 2.	0.976
CPSF3	cstf3	ENSPREP00000006485	ENSPREP00000020056	Cleavage and polyadenylation specific factor 3.	Cleavage stimulation factor, 3' pre-RNA, subunit 3.	0.938
CPSF3	kiaa0232	ENSPREP00000006485	ENSPREP00000032326	Cleavage and polyadenylation specific factor 3.	Zgc:158564.	0.795
CPSF3	nudt21	ENSPREP00000006485	ENSPREP00000001735	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.795