(30 nodes) Small-subunit processome network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pdcd11	Programmed cell death 11. (1810 aa)
	bms1	BMS1 ribosome biogenesis factor. (1311 aa)
	nol10	Nucleolar protein 10. (718 aa)
	nol6	Nucleolar protein 6. (1145 aa)
	wdr43	WD repeat domain 43. (651 aa)
	utp3	UTP3 small subunit processome component. (472 aa)
	ENSPREP00000008270	WD_REPEATS_REGION domain-containing protein. (129 aa)
	utp11	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (252 aa)
	ENSPREP00000008920	Uncharacterized protein. (97 aa)
	imp3	IMP U3 small nucleolar ribonucleoprotein 3. (183 aa)
	noc4l	Nucleolar complex associated 4 homolog. (526 aa)
	utp15	UTP15 small subunit processome component. (528 aa)
	emg1	EMG1 N1-specific pseudouridine methyltransferase. (289 aa)
	LOC103482313	Neuroguidin, EIF4E binding protein. (447 aa)
	utp18	WD_REPEATS_REGION domain-containing protein. (533 aa)
	utp6	UTP6 small subunit processome component. (603 aa)
	utp20	UTP20 small subunit processome component. (2602 aa)
	aatf	Apoptosis antagonizing transcription factor. (548 aa)
	krr1	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (381 aa)
	imp4	IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
	LOC103482453	UTP14C small subunit processome component. (763 aa)
	LOC103473717	PWP2 small subunit processome component. (914 aa)
	dcaf13	Ddb1 and cul4 associated factor 13. (445 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (955 aa)
	wdr46	WD repeat domain 46. (553 aa)
	nop14	NOP14 nucleolar protein homolog (yeast). (871 aa)
	wdr36	WD repeat domain 36. (793 aa)
	utp4	UTP4 small subunit processome component. (684 aa)
	fcf1	FCF1 rRNA-processing protein. (197 aa)
	mphosph10	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (665 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000008270	ENSPREP00000008920	ENSPREP00000008270	ENSPREP00000008920	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.997
ENSPREP00000008270	LOC103473717	ENSPREP00000008270	ENSPREP00000023564	WD_REPEATS_REGION domain-containing protein.	PWP2 small subunit processome component.	0.999
ENSPREP00000008270	LOC103482313	ENSPREP00000008270	ENSPREP00000016575	WD_REPEATS_REGION domain-containing protein.	Neuroguidin, EIF4E binding protein.	0.974
ENSPREP00000008270	LOC103482453	ENSPREP00000008270	ENSPREP00000022763	WD_REPEATS_REGION domain-containing protein.	UTP14C small subunit processome component.	0.995
ENSPREP00000008270	aatf	ENSPREP00000008270	ENSPREP00000019969	WD_REPEATS_REGION domain-containing protein.	Apoptosis antagonizing transcription factor.	0.994
ENSPREP00000008270	bms1	ENSPREP00000008270	ENSPREP00000003768	WD_REPEATS_REGION domain-containing protein.	BMS1 ribosome biogenesis factor.	0.998
ENSPREP00000008270	dcaf13	ENSPREP00000008270	ENSPREP00000023789	WD_REPEATS_REGION domain-containing protein.	Ddb1 and cul4 associated factor 13.	0.996
ENSPREP00000008270	emg1	ENSPREP00000008270	ENSPREP00000015425	WD_REPEATS_REGION domain-containing protein.	EMG1 N1-specific pseudouridine methyltransferase.	0.964
ENSPREP00000008270	fcf1	ENSPREP00000008270	ENSPREP00000028423	WD_REPEATS_REGION domain-containing protein.	FCF1 rRNA-processing protein.	0.976
ENSPREP00000008270	imp3	ENSPREP00000008270	ENSPREP00000010107	WD_REPEATS_REGION domain-containing protein.	IMP U3 small nucleolar ribonucleoprotein 3.	0.985
ENSPREP00000008270	imp4	ENSPREP00000008270	ENSPREP00000020795	WD_REPEATS_REGION domain-containing protein.	IMP U3 small nucleolar ribonucleoprotein 4.	0.996
ENSPREP00000008270	krr1	ENSPREP00000008270	ENSPREP00000020279	WD_REPEATS_REGION domain-containing protein.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.996
ENSPREP00000008270	mphosph10	ENSPREP00000008270	ENSPREP00000033437	WD_REPEATS_REGION domain-containing protein.	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.	0.996
ENSPREP00000008270	nat10	ENSPREP00000008270	ENSPREP00000023915	WD_REPEATS_REGION domain-containing protein.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.995
ENSPREP00000008270	noc4l	ENSPREP00000008270	ENSPREP00000010537	WD_REPEATS_REGION domain-containing protein.	Nucleolar complex associated 4 homolog.	0.998
ENSPREP00000008270	nol10	ENSPREP00000008270	ENSPREP00000006422	WD_REPEATS_REGION domain-containing protein.	Nucleolar protein 10.	0.977
ENSPREP00000008270	nol6	ENSPREP00000008270	ENSPREP00000006993	WD_REPEATS_REGION domain-containing protein.	Nucleolar protein 6.	0.999
ENSPREP00000008270	nop14	ENSPREP00000008270	ENSPREP00000025074	WD_REPEATS_REGION domain-containing protein.	NOP14 nucleolar protein homolog (yeast).	0.993
ENSPREP00000008270	pdcd11	ENSPREP00000008270	ENSPREP00000000637	WD_REPEATS_REGION domain-containing protein.	Programmed cell death 11.	0.990
ENSPREP00000008270	utp11	ENSPREP00000008270	ENSPREP00000008892	WD_REPEATS_REGION domain-containing protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.968