(20 nodes) Dedicator of cytokinesis, and ELMO, armadillo-like helical domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103466819	Engulfment and cell motility 3. (723 aa)
	RHOG	Ras homolog family member G. (113 aa)
	dock11	Dedicator of cytokinesis 11; Belongs to the DOCK family. (2003 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (1017 aa)
	LOC103472297	Engulfment and cell motility 1. (740 aa)
	ENSPREP00000010679	Ras homolog gene family, member Gd. (101 aa)
	LOC103471173	Uncharacterized protein. (191 aa)
	LOC103477993	Uncharacterized protein. (134 aa)
	LOC103478369	Uncharacterized protein. (3064 aa)
	elmo2	Engulfment and cell motility 2. (723 aa)
	LOC103474130	Dedicator of cytokinesis 9b; Belongs to the DOCK family. (2070 aa)
	LOC103464845	Uncharacterized protein; Belongs to the DOCK family. (1871 aa)
	LOC103467511	Uncharacterized protein; Belongs to the DOCK family. (1987 aa)
	ENSPREP00000027742	DOCK_N domain-containing protein. (156 aa)
	ENSPREP00000027775	DHR-1 domain-containing protein; Belongs to the DOCK family. (321 aa)
	ENSPREP00000027808	DHR-2 domain-containing protein; Belongs to the DOCK family. (139 aa)
	Dock2	DHR-2 domain-containing protein; Belongs to the DOCK family. (375 aa)
	LOC103481975-2	Uncharacterized protein. (195 aa)
	LOC103481976	Uncharacterized protein. (193 aa)
	dock10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2188 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF26	ENSPREP00000010679	ENSPREP00000004140	ENSPREP00000010679	Rho guanine nucleotide exchange factor 26.	Ras homolog gene family, member Gd.	0.954
ARHGEF26	LOC103471173	ENSPREP00000004140	ENSPREP00000010689	Rho guanine nucleotide exchange factor 26.	Uncharacterized protein.	0.954
ARHGEF26	RHOG	ENSPREP00000004140	ENSPREP00000001999	Rho guanine nucleotide exchange factor 26.	Ras homolog family member G.	0.954
Dock2	ENSPREP00000010679	ENSPREP00000027818	ENSPREP00000010679	DHR-2 domain-containing protein; Belongs to the DOCK family.	Ras homolog gene family, member Gd.	0.560
Dock2	ENSPREP00000027742	ENSPREP00000027818	ENSPREP00000027742	DHR-2 domain-containing protein; Belongs to the DOCK family.	DOCK_N domain-containing protein.	0.899
Dock2	ENSPREP00000027775	ENSPREP00000027818	ENSPREP00000027775	DHR-2 domain-containing protein; Belongs to the DOCK family.	DHR-1 domain-containing protein; Belongs to the DOCK family.	0.900
Dock2	ENSPREP00000027808	ENSPREP00000027818	ENSPREP00000027808	DHR-2 domain-containing protein; Belongs to the DOCK family.	DHR-2 domain-containing protein; Belongs to the DOCK family.	0.920
Dock2	LOC103466819	ENSPREP00000027818	ENSPREP00000001563	DHR-2 domain-containing protein; Belongs to the DOCK family.	Engulfment and cell motility 3.	0.704
Dock2	LOC103471173	ENSPREP00000027818	ENSPREP00000010689	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.560
Dock2	LOC103472297	ENSPREP00000027818	ENSPREP00000006785	DHR-2 domain-containing protein; Belongs to the DOCK family.	Engulfment and cell motility 1.	0.704
Dock2	LOC103477993	ENSPREP00000027818	ENSPREP00000016909	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.473
Dock2	LOC103478369	ENSPREP00000027818	ENSPREP00000017060	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.408
Dock2	LOC103481975-2	ENSPREP00000027818	ENSPREP00000029676	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.539
Dock2	LOC103481976	ENSPREP00000027818	ENSPREP00000029706	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.539
Dock2	RHOG	ENSPREP00000027818	ENSPREP00000001999	DHR-2 domain-containing protein; Belongs to the DOCK family.	Ras homolog family member G.	0.560
Dock2	elmo2	ENSPREP00000027818	ENSPREP00000019161	DHR-2 domain-containing protein; Belongs to the DOCK family.	Engulfment and cell motility 2.	0.704
ENSPREP00000010679	ARHGEF26	ENSPREP00000010679	ENSPREP00000004140	Ras homolog gene family, member Gd.	Rho guanine nucleotide exchange factor 26.	0.954
ENSPREP00000010679	Dock2	ENSPREP00000010679	ENSPREP00000027818	Ras homolog gene family, member Gd.	DHR-2 domain-containing protein; Belongs to the DOCK family.	0.560
ENSPREP00000010679	ENSPREP00000027742	ENSPREP00000010679	ENSPREP00000027742	Ras homolog gene family, member Gd.	DOCK_N domain-containing protein.	0.560
ENSPREP00000010679	ENSPREP00000027775	ENSPREP00000010679	ENSPREP00000027775	Ras homolog gene family, member Gd.	DHR-1 domain-containing protein; Belongs to the DOCK family.	0.560