(5 nodes) Regulation of Rab protein signal transduction, and DENN domain-containing protein 5A/B network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dennd3	DENN/MADD domain containing 3a. (1265 aa)
	rab28	Uncharacterized protein. (222 aa)
	rab12	RAB12, member RAS oncogene family. (244 aa)
	LOC103478638	UDENN domain-containing protein. (1198 aa)
	dennd5a	DENN/MADD domain containing 5A. (1265 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103478638	rab12	ENSPREP00000028302	ENSPREP00000025898	UDENN domain-containing protein.	RAB12, member RAS oncogene family.	0.697
LOC103478638	rab28	ENSPREP00000028302	ENSPREP00000020511	UDENN domain-containing protein.	Uncharacterized protein.	0.521
dennd3	rab12	ENSPREP00000017589	ENSPREP00000025898	DENN/MADD domain containing 3a.	RAB12, member RAS oncogene family.	0.697
dennd3	rab28	ENSPREP00000017589	ENSPREP00000020511	DENN/MADD domain containing 3a.	Uncharacterized protein.	0.521
dennd5a	rab28	ENSPREP00000034082	ENSPREP00000020511	DENN/MADD domain containing 5A.	Uncharacterized protein.	0.576
rab12	LOC103478638	ENSPREP00000025898	ENSPREP00000028302	RAB12, member RAS oncogene family.	UDENN domain-containing protein.	0.697
rab12	dennd3	ENSPREP00000025898	ENSPREP00000017589	RAB12, member RAS oncogene family.	DENN/MADD domain containing 3a.	0.697
rab28	LOC103478638	ENSPREP00000020511	ENSPREP00000028302	Uncharacterized protein.	UDENN domain-containing protein.	0.521
rab28	dennd3	ENSPREP00000020511	ENSPREP00000017589	Uncharacterized protein.	DENN/MADD domain containing 3a.	0.521
rab28	dennd5a	ENSPREP00000020511	ENSPREP00000034082	Uncharacterized protein.	DENN/MADD domain containing 5A.	0.576