(12 nodes) Mixed, incl. Protein kinase C, delta/epsilon/eta/theta types, and MALT1 immunoglobulin-like domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103478932	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (389 aa)
	LOC103466618	MALT paracaspase 3. (573 aa)
	LOC103469935	MALT paracaspase 1. (828 aa)
	prkcd	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (664 aa)
	ENSPREP00000018398	MALT paracaspase 2. (715 aa)
	ENSPREP00000023044	C2 domain-containing protein. (126 aa)
	prkch	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (553 aa)
	LOC103470783	CARD domain-containing protein. (434 aa)
	LOC103465056	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (640 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (719 aa)
	ENSPREP00000027430	CARD domain-containing protein. (524 aa)
	LOC103468544	Guanylate kinase-like domain-containing protein. (308 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000018398	ENSPREP00000027430	ENSPREP00000018398	ENSPREP00000027430	MALT paracaspase 2.	CARD domain-containing protein.	0.784
ENSPREP00000018398	LOC103465056	ENSPREP00000018398	ENSPREP00000026578	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
ENSPREP00000018398	LOC103468544	ENSPREP00000018398	ENSPREP00000027446	MALT paracaspase 2.	Guanylate kinase-like domain-containing protein.	0.784
ENSPREP00000018398	LOC103470783	ENSPREP00000018398	ENSPREP00000025510	MALT paracaspase 2.	CARD domain-containing protein.	0.472
ENSPREP00000018398	LOC103478932	ENSPREP00000018398	ENSPREP00000002524	MALT paracaspase 2.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.534
ENSPREP00000018398	prkcd	ENSPREP00000018398	ENSPREP00000018282	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
ENSPREP00000018398	prkcq	ENSPREP00000018398	ENSPREP00000027121	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
ENSPREP00000023044	ENSPREP00000027430	ENSPREP00000023044	ENSPREP00000027430	C2 domain-containing protein.	CARD domain-containing protein.	0.559
ENSPREP00000023044	LOC103465056	ENSPREP00000023044	ENSPREP00000026578	C2 domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.414
ENSPREP00000023044	LOC103468544	ENSPREP00000023044	ENSPREP00000027446	C2 domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.559
ENSPREP00000023044	LOC103470783	ENSPREP00000023044	ENSPREP00000025510	C2 domain-containing protein.	CARD domain-containing protein.	0.492
ENSPREP00000023044	prkcd	ENSPREP00000023044	ENSPREP00000018282	C2 domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.414
ENSPREP00000023044	prkch	ENSPREP00000023044	ENSPREP00000023080	C2 domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.868
ENSPREP00000023044	prkcq	ENSPREP00000023044	ENSPREP00000027121	C2 domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.414
ENSPREP00000027430	ENSPREP00000018398	ENSPREP00000027430	ENSPREP00000018398	CARD domain-containing protein.	MALT paracaspase 2.	0.784
ENSPREP00000027430	ENSPREP00000023044	ENSPREP00000027430	ENSPREP00000023044	CARD domain-containing protein.	C2 domain-containing protein.	0.559
ENSPREP00000027430	LOC103465056	ENSPREP00000027430	ENSPREP00000026578	CARD domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.716
ENSPREP00000027430	LOC103466618	ENSPREP00000027430	ENSPREP00000011487	CARD domain-containing protein.	MALT paracaspase 3.	0.784
ENSPREP00000027430	LOC103468544	ENSPREP00000027430	ENSPREP00000027446	CARD domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.900
ENSPREP00000027430	LOC103469935	ENSPREP00000027430	ENSPREP00000011835	CARD domain-containing protein.	MALT paracaspase 1.	0.784