(43 nodes) Synaptic vesicle exocytosis, and Synaptobrevin/Vesicle-associated membrane protein network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000000351	Complexin 2, like. (134 aa)
	LOC103472839	Vesicle-associated membrane protein 1. (150 aa)
	stx1a	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (368 aa)
	LOC103469661	Syntaxin 2b; Belongs to the syntaxin family. (293 aa)
	ENSPREP00000002501	Vesicle-associated membrane protein 2. (122 aa)
	ENSPREP00000004746	V-SNARE coiled-coil homology domain-containing protein. (94 aa)
	LOC103457516	t-SNARE coiled-coil homology domain-containing protein. (296 aa)
	LOC103467654	Synaptotagmin IIa. (430 aa)
	LOC103463266	RAB3B, member RAS oncogene family. (217 aa)
	stxbp2	Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (586 aa)
	UNC13C	Unc-13 homolog C. (2664 aa)
	ENSPREP00000008454	C2 domain-containing protein. (216 aa)
	LOC103466664	Synaptotagmin Ib. (387 aa)
	ENSPREP00000009573	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (140 aa)
	ENSPREP00000009606	Zgc:113149. (298 aa)
	ENSPREP00000011853	Uncharacterized protein. (755 aa)
	LOC103467585	Synapsin IIa. (467 aa)
	LOC103462615	C2 domain-containing protein. (380 aa)
	unc13a	Uncharacterized protein. (1552 aa)
	LOC103474139	Si:ch211-105f12.2. (209 aa)
	ENSPREP00000016345	Zgc:92912. (125 aa)
	SYT2	Synaptotagmin 2. (413 aa)
	stx1b	Syntaxin 1B; Belongs to the syntaxin family. (312 aa)
	snap23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (229 aa)
	LOC103468508	Uncharacterized protein. (221 aa)
	LOC103481737	Syntaxin 4; Belongs to the syntaxin family. (294 aa)
	Cplx2	Complexin 2. (227 aa)
	ENSPREP00000022805	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	LOC103472577	Uncharacterized protein. (1105 aa)
	LOC103463013	PTPRF interacting protein alpha 1. (1183 aa)
	stx11	Syntaxin 11a; Belongs to the syntaxin family. (288 aa)
	SYN3	Synapsin III. (548 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1303 aa)
	syt11	Synaptotagmin XIb. (468 aa)
	LOC103469646	Syntaxin binding protein 1b; Belongs to the STXBP/unc-18/SEC1 family. (547 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (323 aa)
	ENSPREP00000026258	Solute carrier family 18 member 3a. (511 aa)
	rab3c	RAB3C, member RAS oncogene family. (219 aa)
	snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (204 aa)
	LOC103481238	Synaptotagmin Vb. (424 aa)
	LOC103470421	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (285 aa)
	syt1	Synaptotagmin Ia. (422 aa)
	stxbp3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cplx2	ENSPREP00000002501	ENSPREP00000022098	ENSPREP00000002501	Complexin 2.	Vesicle-associated membrane protein 2.	0.435
Cplx2	ENSPREP00000004746	ENSPREP00000022098	ENSPREP00000004746	Complexin 2.	V-SNARE coiled-coil homology domain-containing protein.	0.434
Cplx2	ENSPREP00000008454	ENSPREP00000022098	ENSPREP00000008454	Complexin 2.	C2 domain-containing protein.	0.507
Cplx2	ENSPREP00000009573	ENSPREP00000022098	ENSPREP00000009573	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.531
Cplx2	ENSPREP00000009606	ENSPREP00000022098	ENSPREP00000009606	Complexin 2.	Zgc:113149.	0.515
Cplx2	ENSPREP00000016345	ENSPREP00000022098	ENSPREP00000016345	Complexin 2.	Zgc:92912.	0.435
Cplx2	ENSPREP00000022805	ENSPREP00000022098	ENSPREP00000022805	Complexin 2.	V-SNARE coiled-coil homology domain-containing protein.	0.434
Cplx2	LOC103457516	ENSPREP00000022098	ENSPREP00000005732	Complexin 2.	t-SNARE coiled-coil homology domain-containing protein.	0.467
Cplx2	LOC103463266	ENSPREP00000022098	ENSPREP00000008163	Complexin 2.	RAB3B, member RAS oncogene family.	0.474
Cplx2	LOC103467585	ENSPREP00000022098	ENSPREP00000012015	Complexin 2.	Synapsin IIa.	0.461
Cplx2	LOC103468508	ENSPREP00000022098	ENSPREP00000019661	Complexin 2.	Uncharacterized protein.	0.474
Cplx2	LOC103469646	ENSPREP00000022098	ENSPREP00000024961	Complexin 2.	Syntaxin binding protein 1b; Belongs to the STXBP/unc-18/SEC1 family.	0.518
Cplx2	LOC103469661	ENSPREP00000022098	ENSPREP00000002499	Complexin 2.	Syntaxin 2b; Belongs to the syntaxin family.	0.467
Cplx2	LOC103470421	ENSPREP00000022098	ENSPREP00000032381	Complexin 2.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.467
Cplx2	LOC103472577	ENSPREP00000022098	ENSPREP00000023069	Complexin 2.	Uncharacterized protein.	0.960
Cplx2	LOC103472839	ENSPREP00000022098	ENSPREP00000001577	Complexin 2.	Vesicle-associated membrane protein 1.	0.435
Cplx2	LOC103481737	ENSPREP00000022098	ENSPREP00000019745	Complexin 2.	Syntaxin 4; Belongs to the syntaxin family.	0.467
Cplx2	RIMS2	ENSPREP00000022098	ENSPREP00000023895	Complexin 2.	Regulating synaptic membrane exocytosis 2.	0.960
Cplx2	SYN3	ENSPREP00000022098	ENSPREP00000023800	Complexin 2.	Synapsin III.	0.461
Cplx2	UNC13C	ENSPREP00000022098	ENSPREP00000008426	Complexin 2.	Unc-13 homolog C.	0.507