(103 nodes) Mixed, incl. Nicotinamide salvaging, and Defense response to virus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103470788	NAD(P)(+)--arginine ADP-ribosyltransferase. (264 aa)
	LOC103466215	Poly (ADP-ribose) polymerase family, member 12a. (703 aa)
	LOC103466217	Poly (ADP-ribose) polymerase family, member 12a. (697 aa)
	LOC103474654	Tetratricopeptide repeat domain 9B. (255 aa)
	LOC103457994	Zinc finger protein 292b. (2580 aa)
	LOC103466236	HECT domain-containing protein. (1004 aa)
	rnf213	Ring finger protein 213a. (4763 aa)
	setbp1	SET binding protein 1. (1512 aa)
	LOC103459238	Poly [ADP-ribose] polymerase. (306 aa)
	LOC103459239	Poly [ADP-ribose] polymerase. (299 aa)
	PARP11	Poly [ADP-ribose] polymerase. (304 aa)
	ENSPREP00000004459	Uncharacterized protein. (181 aa)
	ENSPREP00000005088	Poly [ADP-ribose] polymerase. (323 aa)
	zbtb2	Zinc finger and BTB domain containing 2b. (524 aa)
	LOC103468800	Bloodthirsty-related gene family, member 2. (440 aa)
	mettl8	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (395 aa)
	LOC103475402	Serine/threonine kinase 10. (717 aa)
	adprhl2	ADP-ribosylhydrolase like 2. (383 aa)
	LOC103477800	Thyroid hormone receptor associated protein 3a. (907 aa)
	ENSPREP00000009110	Macro domain-containing protein. (171 aa)
	ENSPREP00000009629	TLDc domain-containing protein. (196 aa)
	LOC103480244	Ig-like domain-containing protein. (410 aa)
	LOC103476645	Nescient helix loop helix 2. (124 aa)
	ENSPREP00000009937	Macro domain-containing protein. (276 aa)
	ENSPREP00000010060	Uncharacterized protein. (139 aa)
	rnf13	Ring finger protein 13. (378 aa)
	LOC103472377	zf-3CxxC domain-containing protein. (172 aa)
	ENSPREP00000010946	Poly [ADP-ribose] polymerase. (303 aa)
	ifih1	Interferon induced with helicase C domain 1. (969 aa)
	LOC103466931	Zgc:153219. (318 aa)
	LOC103477270	Uncharacterized protein. (689 aa)
	ENSPREP00000011628	Uncharacterized protein. (564 aa)
	LOC103477355	Protein kinase domain-containing protein. (582 aa)
	ENSPREP00000012170	SH3 domain-containing protein. (149 aa)
	mia3	Uncharacterized protein. (801 aa)
	hivep1	Human immunodeficiency virus type I enhancer binding protein 1. (2369 aa)
	LOC103474874	Hairy-related 8.2. (199 aa)
	LOC103471635	Ligand of numb-protein X 2b. (686 aa)
	SH2D7	SH2 domain containing 7. (444 aa)
	LOC103468247	TLDc domain-containing protein. (444 aa)
	znfx1	Zinc finger, NFX1-type containing 1. (1816 aa)
	xaf1	XIAP associated factor 1. (267 aa)
	LOC103473071	Thyroid hormone receptor associated protein 3b. (886 aa)
	LOC103475595	Reticulon 4 receptor-like 1a. (454 aa)
	hic2	Hypermethylated in cancer 2. (586 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (681 aa)
	spon2	Spondin 2b, extracellular matrix protein. (338 aa)
	klhl15	Kelch-like family member 15. (671 aa)
	ice1	Uncharacterized protein. (1479 aa)
	ENSPREP00000017137	Ras association domain family member 11. (117 aa)
	LOC103463314	G domain-containing protein. (480 aa)
	ENSPREP00000017493	TLDc domain-containing protein. (383 aa)
	LOC103463495	G domain-containing protein. (278 aa)
	LOC103463313	TLDc domain-containing protein. (464 aa)
	LOC103460992	Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (847 aa)
	clg4h19orf44	DUF4614 domain-containing protein. (694 aa)
	LOC103476345	Kruppel-like factor 5 like. (390 aa)
	cramp1	Cramped chromatin regulator homolog 1. (1162 aa)
	LOC103476796	Multiple inositol-polyphosphate phosphatase 1a; Belongs to the histidine acid phosphatase family. (457 aa)
	ENSPREP00000022539	RING-type domain-containing protein. (198 aa)
	ENSPREP00000022586	RING-type domain-containing protein. (205 aa)
	pcnx4	Pecanex 4. (1182 aa)
	macrod1	Mono-ADP ribosylhydrolase 1. (366 aa)
	parp16	Poly [ADP-ribose] polymerase. (316 aa)
	gon4l	Myb-like domain-containing protein. (1572 aa)
	ENSPREP00000023875	Uncharacterized protein. (260 aa)
	ENSPREP00000023886	Uncharacterized protein. (151 aa)
	dnajc28	DnaJ (Hsp40) homolog, subfamily C, member 28. (385 aa)
	PRAG1	PEAK1 related, kinase-activating pseudokinase 1. (1354 aa)
	ENSPREP00000025112	Macro domain-containing protein. (173 aa)
	LOC103469642	Si:dkey-3h3.3. (444 aa)
	ENSPREP00000025444	Poly [ADP-ribose] polymerase. (1527 aa)
	adar	Adenosine deaminase RNA specific. (1358 aa)
	tmx2	Thioredoxin-related transmembrane protein 2a. (300 aa)
	LOC103465032	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (636 aa)
	sh3bp5	SH3-domain binding protein 5b (BTK-associated). (464 aa)
	LOC108165898	Poly (ADP-ribose) polymerase family, member 12b. (427 aa)
	LOC103461817	Uncharacterized protein. (797 aa)
	ENSPREP00000028311	Uncharacterized protein. (97 aa)
	ENSPREP00000028349	Poly [ADP-ribose] polymerase. (720 aa)
	LOC103465031	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (646 aa)
	ENSPREP00000028395	Uncharacterized protein. (136 aa)
	ENSPREP00000028501	Poly [ADP-ribose] polymerase. (672 aa)
	ENSPREP00000028525	Uncharacterized protein. (254 aa)
	ENSPREP00000028585	Macro domain-containing protein. (508 aa)
	gdap2	Ganglioside induced differentiation associated protein 2. (496 aa)
	LOC103465029	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (618 aa)
	fam162a	Family with sequence similarity 162 member A. (142 aa)
	arl6ip4	ADP-ribosylation factor-like 6 interacting protein 4. (240 aa)
	rsad2	Radical S-adenosyl methionine domain containing 2. (350 aa)
	LOC103458569	Coiled-coil domain containing 28B. (212 aa)
	pex26	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family. (317 aa)
	ENSPREP00000032579	Uncharacterized protein. (100 aa)
	ENSPREP00000032590	Uncharacterized protein. (88 aa)
	LOC103458582	Si:dkey-188i13.10. (96 aa)
	LOC103458581	Uncharacterized protein. (122 aa)
	LOC103458585	Uncharacterized protein. (305 aa)
	LOC103458720	Interferon alpha inducible protein 27 like 2. (135 aa)
	LOC103467314	RING-type domain-containing protein. (198 aa)
	LOC103467312	Zgc:66440. (395 aa)
	LOC103470774	Thioredoxin domain-containing protein. (303 aa)
	ccdc30	Coiled-coil domain containing 30. (1308 aa)
	ENSPREP00000033874	C1q domain-containing protein. (182 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000004459	ifih1	ENSPREP00000004459	ENSPREP00000011433	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.551
ENSPREP00000004459	pex26	ENSPREP00000004459	ENSPREP00000032460	Uncharacterized protein.	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family.	0.605
ENSPREP00000004459	rsad2	ENSPREP00000004459	ENSPREP00000031618	Uncharacterized protein.	Radical S-adenosyl methionine domain containing 2.	0.552
ENSPREP00000005088	ENSPREP00000028525	ENSPREP00000005088	ENSPREP00000028525	Poly [ADP-ribose] polymerase.	Uncharacterized protein.	0.530
ENSPREP00000005088	ENSPREP00000028585	ENSPREP00000005088	ENSPREP00000028585	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.644
ENSPREP00000009110	adprhl2	ENSPREP00000009110	ENSPREP00000008081	Macro domain-containing protein.	ADP-ribosylhydrolase like 2.	0.469
ENSPREP00000009629	ENSPREP00000011628	ENSPREP00000009629	ENSPREP00000011628	TLDc domain-containing protein.	Uncharacterized protein.	0.413
ENSPREP00000009629	LOC103477270	ENSPREP00000009629	ENSPREP00000011565	TLDc domain-containing protein.	Uncharacterized protein.	0.413
ENSPREP00000009629	LOC103477355	ENSPREP00000009629	ENSPREP00000011646	TLDc domain-containing protein.	Protein kinase domain-containing protein.	0.413
ENSPREP00000009629	ifih1	ENSPREP00000009629	ENSPREP00000011433	TLDc domain-containing protein.	Interferon induced with helicase C domain 1.	0.449
ENSPREP00000009629	pex26	ENSPREP00000009629	ENSPREP00000032460	TLDc domain-containing protein.	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family.	0.467
ENSPREP00000009629	rsad2	ENSPREP00000009629	ENSPREP00000031618	TLDc domain-containing protein.	Radical S-adenosyl methionine domain containing 2.	0.737
ENSPREP00000009629	xaf1	ENSPREP00000009629	ENSPREP00000014411	TLDc domain-containing protein.	XIAP associated factor 1.	0.640
ENSPREP00000009937	ENSPREP00000010946	ENSPREP00000009937	ENSPREP00000010946	Macro domain-containing protein.	Poly [ADP-ribose] polymerase.	0.512
ENSPREP00000010946	ENSPREP00000009937	ENSPREP00000010946	ENSPREP00000009937	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.512
ENSPREP00000010946	ENSPREP00000028585	ENSPREP00000010946	ENSPREP00000028585	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.889
ENSPREP00000011628	ENSPREP00000009629	ENSPREP00000011628	ENSPREP00000009629	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	ENSPREP00000017493	ENSPREP00000011628	ENSPREP00000017493	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	LOC103463313	ENSPREP00000011628	ENSPREP00000017671	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	LOC103463314	ENSPREP00000011628	ENSPREP00000017454	Uncharacterized protein.	G domain-containing protein.	0.413