(53 nodes) Nicotinamide salvaging, and Defense response to virus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103470788	NAD(P)(+)--arginine ADP-ribosyltransferase. (264 aa)
	LOC103466215	Poly (ADP-ribose) polymerase family, member 12a. (703 aa)
	LOC103466217	Poly (ADP-ribose) polymerase family, member 12a. (697 aa)
	LOC103466236	HECT domain-containing protein. (1004 aa)
	rnf213	Ring finger protein 213a. (4763 aa)
	ENSPREP00000004459	Uncharacterized protein. (181 aa)
	ENSPREP00000005088	Poly [ADP-ribose] polymerase. (323 aa)
	adprhl2	ADP-ribosylhydrolase like 2. (383 aa)
	ENSPREP00000009110	Macro domain-containing protein. (171 aa)
	ENSPREP00000009629	TLDc domain-containing protein. (196 aa)
	LOC103476645	Nescient helix loop helix 2. (124 aa)
	ENSPREP00000009937	Macro domain-containing protein. (276 aa)
	ENSPREP00000010060	Uncharacterized protein. (139 aa)
	LOC103472377	zf-3CxxC domain-containing protein. (172 aa)
	ENSPREP00000010946	Poly [ADP-ribose] polymerase. (303 aa)
	ifih1	Interferon induced with helicase C domain 1. (969 aa)
	LOC103477270	Uncharacterized protein. (689 aa)
	ENSPREP00000011628	Uncharacterized protein. (564 aa)
	LOC103477355	Protein kinase domain-containing protein. (582 aa)
	LOC103468247	TLDc domain-containing protein. (444 aa)
	xaf1	XIAP associated factor 1. (267 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (681 aa)
	LOC103463314	G domain-containing protein. (480 aa)
	ENSPREP00000017493	TLDc domain-containing protein. (383 aa)
	LOC103463495	G domain-containing protein. (278 aa)
	LOC103463313	TLDc domain-containing protein. (464 aa)
	ENSPREP00000022539	RING-type domain-containing protein. (198 aa)
	ENSPREP00000022586	RING-type domain-containing protein. (205 aa)
	macrod1	Mono-ADP ribosylhydrolase 1. (366 aa)
	ENSPREP00000025112	Macro domain-containing protein. (173 aa)
	LOC103469642	Si:dkey-3h3.3. (444 aa)
	ENSPREP00000025444	Poly [ADP-ribose] polymerase. (1527 aa)
	tmx2	Thioredoxin-related transmembrane protein 2a. (300 aa)
	LOC103465032	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (636 aa)
	LOC103461817	Uncharacterized protein. (797 aa)
	ENSPREP00000028311	Uncharacterized protein. (97 aa)
	ENSPREP00000028349	Poly [ADP-ribose] polymerase. (720 aa)
	LOC103465031	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (646 aa)
	ENSPREP00000028395	Uncharacterized protein. (136 aa)
	ENSPREP00000028501	Poly [ADP-ribose] polymerase. (672 aa)
	ENSPREP00000028525	Uncharacterized protein. (254 aa)
	ENSPREP00000028585	Macro domain-containing protein. (508 aa)
	gdap2	Ganglioside induced differentiation associated protein 2. (496 aa)
	LOC103465029	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (618 aa)
	fam162a	Family with sequence similarity 162 member A. (142 aa)
	rsad2	Radical S-adenosyl methionine domain containing 2. (350 aa)
	pex26	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family. (317 aa)
	ENSPREP00000032590	Uncharacterized protein. (88 aa)
	LOC103458582	Si:dkey-188i13.10. (96 aa)
	LOC103458720	Interferon alpha inducible protein 27 like 2. (135 aa)
	LOC103467314	RING-type domain-containing protein. (198 aa)
	LOC103467312	Zgc:66440. (395 aa)
	LOC103470774	Thioredoxin domain-containing protein. (303 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000004459	ifih1	ENSPREP00000004459	ENSPREP00000011433	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.551
ENSPREP00000004459	pex26	ENSPREP00000004459	ENSPREP00000032460	Uncharacterized protein.	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family.	0.605
ENSPREP00000004459	rsad2	ENSPREP00000004459	ENSPREP00000031618	Uncharacterized protein.	Radical S-adenosyl methionine domain containing 2.	0.552
ENSPREP00000005088	ENSPREP00000028525	ENSPREP00000005088	ENSPREP00000028525	Poly [ADP-ribose] polymerase.	Uncharacterized protein.	0.530
ENSPREP00000005088	ENSPREP00000028585	ENSPREP00000005088	ENSPREP00000028585	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.644
ENSPREP00000009110	adprhl2	ENSPREP00000009110	ENSPREP00000008081	Macro domain-containing protein.	ADP-ribosylhydrolase like 2.	0.469
ENSPREP00000009629	ENSPREP00000011628	ENSPREP00000009629	ENSPREP00000011628	TLDc domain-containing protein.	Uncharacterized protein.	0.413
ENSPREP00000009629	LOC103477270	ENSPREP00000009629	ENSPREP00000011565	TLDc domain-containing protein.	Uncharacterized protein.	0.413
ENSPREP00000009629	LOC103477355	ENSPREP00000009629	ENSPREP00000011646	TLDc domain-containing protein.	Protein kinase domain-containing protein.	0.413
ENSPREP00000009629	ifih1	ENSPREP00000009629	ENSPREP00000011433	TLDc domain-containing protein.	Interferon induced with helicase C domain 1.	0.449
ENSPREP00000009629	pex26	ENSPREP00000009629	ENSPREP00000032460	TLDc domain-containing protein.	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family.	0.467
ENSPREP00000009629	rsad2	ENSPREP00000009629	ENSPREP00000031618	TLDc domain-containing protein.	Radical S-adenosyl methionine domain containing 2.	0.737
ENSPREP00000009629	xaf1	ENSPREP00000009629	ENSPREP00000014411	TLDc domain-containing protein.	XIAP associated factor 1.	0.640
ENSPREP00000009937	ENSPREP00000010946	ENSPREP00000009937	ENSPREP00000010946	Macro domain-containing protein.	Poly [ADP-ribose] polymerase.	0.512
ENSPREP00000010946	ENSPREP00000009937	ENSPREP00000010946	ENSPREP00000009937	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.512
ENSPREP00000010946	ENSPREP00000028585	ENSPREP00000010946	ENSPREP00000028585	Poly [ADP-ribose] polymerase.	Macro domain-containing protein.	0.889
ENSPREP00000011628	ENSPREP00000009629	ENSPREP00000011628	ENSPREP00000009629	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	ENSPREP00000017493	ENSPREP00000011628	ENSPREP00000017493	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	LOC103463313	ENSPREP00000011628	ENSPREP00000017671	Uncharacterized protein.	TLDc domain-containing protein.	0.413
ENSPREP00000011628	LOC103463314	ENSPREP00000011628	ENSPREP00000017454	Uncharacterized protein.	G domain-containing protein.	0.413