(6 nodes) Mixed, incl. Aveugle-like, SAM domain, and The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity. network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000001825	RING-CH-type domain-containing protein. (923 aa)
	SAMD12	Sterile alpha motif domain containing 12. (203 aa)
	stard7	StAR-related lipid transfer (START) domain containing 7. (410 aa)
	cmbl	Carboxymethylenebutenolidase homolog (Pseudomonas). (257 aa)
	MARCHF6	Membrane associated ring-CH-type finger 6. (932 aa)
	ropn1l	Rhophilin associated tail protein 1-like. (225 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001825	SAMD12	ENSPREP00000001825	ENSPREP00000003527	RING-CH-type domain-containing protein.	Sterile alpha motif domain containing 12.	0.597
ENSPREP00000001825	cmbl	ENSPREP00000001825	ENSPREP00000021059	RING-CH-type domain-containing protein.	Carboxymethylenebutenolidase homolog (Pseudomonas).	0.693
ENSPREP00000001825	ropn1l	ENSPREP00000001825	ENSPREP00000024348	RING-CH-type domain-containing protein.	Rhophilin associated tail protein 1-like.	0.715
ENSPREP00000001825	stard7	ENSPREP00000001825	ENSPREP00000015370	RING-CH-type domain-containing protein.	StAR-related lipid transfer (START) domain containing 7.	0.689
MARCHF6	SAMD12	ENSPREP00000021101	ENSPREP00000003527	Membrane associated ring-CH-type finger 6.	Sterile alpha motif domain containing 12.	0.597
MARCHF6	cmbl	ENSPREP00000021101	ENSPREP00000021059	Membrane associated ring-CH-type finger 6.	Carboxymethylenebutenolidase homolog (Pseudomonas).	0.693
MARCHF6	ropn1l	ENSPREP00000021101	ENSPREP00000024348	Membrane associated ring-CH-type finger 6.	Rhophilin associated tail protein 1-like.	0.723
MARCHF6	stard7	ENSPREP00000021101	ENSPREP00000015370	Membrane associated ring-CH-type finger 6.	StAR-related lipid transfer (START) domain containing 7.	0.689
SAMD12	ENSPREP00000001825	ENSPREP00000003527	ENSPREP00000001825	Sterile alpha motif domain containing 12.	RING-CH-type domain-containing protein.	0.597
SAMD12	MARCHF6	ENSPREP00000003527	ENSPREP00000021101	Sterile alpha motif domain containing 12.	Membrane associated ring-CH-type finger 6.	0.597
SAMD12	cmbl	ENSPREP00000003527	ENSPREP00000021059	Sterile alpha motif domain containing 12.	Carboxymethylenebutenolidase homolog (Pseudomonas).	0.408
SAMD12	stard7	ENSPREP00000003527	ENSPREP00000015370	Sterile alpha motif domain containing 12.	StAR-related lipid transfer (START) domain containing 7.	0.659
cmbl	ENSPREP00000001825	ENSPREP00000021059	ENSPREP00000001825	Carboxymethylenebutenolidase homolog (Pseudomonas).	RING-CH-type domain-containing protein.	0.693
cmbl	MARCHF6	ENSPREP00000021059	ENSPREP00000021101	Carboxymethylenebutenolidase homolog (Pseudomonas).	Membrane associated ring-CH-type finger 6.	0.693
cmbl	SAMD12	ENSPREP00000021059	ENSPREP00000003527	Carboxymethylenebutenolidase homolog (Pseudomonas).	Sterile alpha motif domain containing 12.	0.408
cmbl	ropn1l	ENSPREP00000021059	ENSPREP00000024348	Carboxymethylenebutenolidase homolog (Pseudomonas).	Rhophilin associated tail protein 1-like.	0.631
cmbl	stard7	ENSPREP00000021059	ENSPREP00000015370	Carboxymethylenebutenolidase homolog (Pseudomonas).	StAR-related lipid transfer (START) domain containing 7.	0.417
ropn1l	ENSPREP00000001825	ENSPREP00000024348	ENSPREP00000001825	Rhophilin associated tail protein 1-like.	RING-CH-type domain-containing protein.	0.715
ropn1l	MARCHF6	ENSPREP00000024348	ENSPREP00000021101	Rhophilin associated tail protein 1-like.	Membrane associated ring-CH-type finger 6.	0.723
ropn1l	cmbl	ENSPREP00000024348	ENSPREP00000021059	Rhophilin associated tail protein 1-like.	Carboxymethylenebutenolidase homolog (Pseudomonas).	0.631