(6 nodes) Mixed, incl. G-quadruplex DNA unwinding, and Positive regulation of NLRP3 inflammasome complex assembly network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103464681	DEAD-box helicase 17; Belongs to the DEAD box helicase family. (651 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
	dhx29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1373 aa)
	DDX41	DEAD-box helicase 41. (614 aa)
	dhx33	DEAH (Asp-Glu-Ala-His) box polypeptide 33. (682 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1216 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX41	LOC103464681	ENSPREP00000007803	ENSPREP00000000681	DEAD-box helicase 41.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.485
DDX41	dhx29	ENSPREP00000007803	ENSPREP00000004313	DEAD-box helicase 41.	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	0.617
DDX41	dhx33	ENSPREP00000007803	ENSPREP00000012151	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 33.	0.679
DDX41	dhx36	ENSPREP00000007803	ENSPREP00000004177	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	0.703
DDX41	dhx9	ENSPREP00000007803	ENSPREP00000028546	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.716
LOC103464681	DDX41	ENSPREP00000000681	ENSPREP00000007803	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 41.	0.485
LOC103464681	dhx29	ENSPREP00000000681	ENSPREP00000004313	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	0.736
LOC103464681	dhx33	ENSPREP00000000681	ENSPREP00000012151	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH (Asp-Glu-Ala-His) box polypeptide 33.	0.742
LOC103464681	dhx36	ENSPREP00000000681	ENSPREP00000004177	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	0.735
LOC103464681	dhx9	ENSPREP00000000681	ENSPREP00000028546	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.891
dhx29	DDX41	ENSPREP00000004313	ENSPREP00000007803	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	DEAD-box helicase 41.	0.617
dhx29	LOC103464681	ENSPREP00000004313	ENSPREP00000000681	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.736
dhx29	dhx9	ENSPREP00000004313	ENSPREP00000028546	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.665
dhx33	DDX41	ENSPREP00000012151	ENSPREP00000007803	DEAH (Asp-Glu-Ala-His) box polypeptide 33.	DEAD-box helicase 41.	0.679
dhx33	LOC103464681	ENSPREP00000012151	ENSPREP00000000681	DEAH (Asp-Glu-Ala-His) box polypeptide 33.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.742
dhx36	DDX41	ENSPREP00000004177	ENSPREP00000007803	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	DEAD-box helicase 41.	0.703
dhx36	LOC103464681	ENSPREP00000004177	ENSPREP00000000681	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.735
dhx36	dhx9	ENSPREP00000004177	ENSPREP00000028546	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.722
dhx9	DDX41	ENSPREP00000028546	ENSPREP00000007803	DEAH (Asp-Glu-Ala-His) box helicase 9.	DEAD-box helicase 41.	0.716
dhx9	LOC103464681	ENSPREP00000028546	ENSPREP00000000681	DEAH (Asp-Glu-Ala-His) box helicase 9.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.891